Journals / Eurasian Journal of Pulmonology / 2019 / Cilt: 21 - Sayı: 3

Double whammy: A rare disorder complicating a common infection – A case report and review of literature

Pages
207–211
Publication Date
2022-10-18
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Gorham-stout disease (gsd), is a rare disorder of unknown etiology. although a non-malignant,non-infectious condition, gsd results in massive destruction of bones by osteolysis secondary toproliferation of blood vessels. we present a young man afflicted with this condition with coexistingtuberculous pleural effusion and the successful outcome with treatment.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Gorham-stout disease (gsd), is a rare disorder of unknown etiology. although a non-malignant,non-infectious condition, gsd results in massive destruction of bones by osteolysis secondary toproliferation of blood vessels. we present a young man afflicted with this condition with coexistingtuberculous pleural effusion and the successful outcome with treatment.
📊
Key Findings & Data:Gorham-stout disease (gsd), is a rare disorder of unknown etiology. although a non-malignant,non-infectious condition, gsd results in massive destruction of bones by osteolysis secondary toproliferation of blood vessels. we present a young man afflicted with this condition with coexistingtuberculous pleural effusion and the successful outcome with treatment.
💡
Conclusion & Impact:Gorham-stout disease (gsd), is a rare disorder of unknown etiology. although a non-malignant,non-infectious condition, gsd results in massive destruction of bones by osteolysis secondary toproliferation of blood vessels. we present a young man afflicted with this condition with coexistingtuberculous pleural effusion and the successful outcome with treatment.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Gorham-stout disease (gsd), is a rare disorder of unknown etiology. although a non-malignant,non-infectious condition, gsd results in massive destruction of bones by osteolysis secondary toproliferation of blood vessels. we present a young man afflicted with this condition with coexistingtuberculous pleural effusion and the successful outcome with treatment.

🔖

Cite This Article

DEVARAJ, U., K, U. M., RAMACHANDRAN, P. (2022). Double whammy: A rare disorder complicating a common infection – A case report and review of literature. Eurasian Journal of Pulmonology, Cilt: 21 - Sayı: 3, 207–211. https://ajindex.com/articles/509657

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (17)

  1. Patel DV. Gorham’s disease or massive osteolysis. Clin Med Res 2005
  2. 65‑74. 2. Gorham LW, Stout AP. Massive osteolysis (acute spontaneous absorption of bone, phantom bone, disappearing bone)
  3. its relation to hemangiomatosis. J Bone Joint Surg Am 1955
  4. 37‑A: 985‑1004. 3. Dellinger MT, Garg N, Olsen BR. Viewpoints on vessels and vanishing bones in Gorham‑stout disease. Bone 2014
  5. 47‑52. 4. Hirayama T, Sabokbar A, Itonaga I, Watt‑Smith S, Athanasou NA. Cellular and humoral mechanisms of osteoclast formation and bone resorption in gorham‑stout disease. J Pathol 2001
  6. 624‑30. 5. Devlin RD, Bone HG 3rd, Roodman GD. Interleukin‑6: A potential mediator of the massive osteolysis in patients with Gorham‑stout disease. J Clin Endocrinol Metab 1996
  7. 1893‑7. 6. Heyden G, Kindblom LG, Nielsen JM. Disappearing bone disease. A clinical and histological study. J Bone Joint Surg Am 1977
  8. 57‑61. 7. Radhakrishnan K, Rockson SG. Gorham’s disease: An osseous disease of lymphangiogenesis? Ann N Y Acad Sci 2008
  9. 203‑5. 8. Colucci S, Taraboletti G, Primo L, Viale A, Roca C, Valdembri D, et al. Gorham‑Stout syndrome: A monocyte‑mediated cytokine propelled disease. J Bone Miner Res 2006
  10. 207‑18. 9. Liu Y, Zhong DR, Zhou PR, Lv F, Ma DD, Xia WB, et al. Gorham‑stout disease: Radiological, histological, and clinical features of 12 cases and review of literature. Clin Rheumatol 2016
  11. 813‑23. 10. Noman S, Faiz S, Khan SA, Sattar A. Massive osteolysis in distal shaft of humerus: A case report on vanishing bone disease. J Coll Physicians Surg Pak 2018
  12. S164‑5. 11. Jindal M, Garg K. Vanishing bone tumor (Gorham‑stout syndrome): A case report. Transl Sci Rare Dis 2017
  13. 73‑6. 12. El‑Kouba G, de Araújo Santos R, Pilluski PC, Severo A, Lech O. Gorham‑stout syndrome: Phantom bone disease. Rev Bras Ortop 2010
  14. 618‑22. 13. Kuriyama DK, McElligott SC, Glaser DW, Thompson KS. Treatment of Gorham‑stout disease with zoledronic acid and interferon‑α: A case report and literature review. J Pediatr Hematol Oncol 2010
  15. 579‑84. 14. Takahashi A, Ogawa C, Kanazawa T, Watanabe H, Suzuki M, Suzuki N, et al. Remission induced by interferon alfa in a patient with massive osteolysis and extension of lymph‑hemangiomatosis: A severe case of Gorham‑stout syndrome. J Pediatr Surg 2005
  16. E47‑50. 15. Tie ML, Poland GA, Rosenow EC 3rd. Chylothorax in gorham’s syndrome. A common complication of a rare disease. Chest 1994
  17. 208‑13. 16. Kotaru AC, Rajput AK. Chylothorax from Gorham‑stout disease.