Journals / Eurasian Journal of Medicine / 2015 / Cilt: 47 - Sayı: 2

Dirençli Hipertansif, Kontrollü Hipertansif ve Normotansif Hastalarda Ortalama Trombosit Hacminin Değerlendirilmesi

Assessment of Mean Platelet Volume in Patients with Resistant Hypertension, Controlled Hypertension and Normotensives

Pages
79–84
Publication Date
2022-10-18
DOI
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Results: The mean platelet volume levels were significantly higher inRHTN group than in the CHTN and normotensive groups (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Patients with resistant hypertension are at increasedrisk for cardiovascular events.
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Key Findings & Data:Materials and Methods: 279 consecutive patients were included inthis study.
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Conclusion & Impact:Results: The mean platelet volume levels were significantly higher inRHTN group than in the CHTN and normotensive groups (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Patients with resistant hypertension are at increasedrisk for cardiovascular events. Mean platelet volume (MPV) is an accepted biomarker of platelet activation and considered as a risk factor for cardiovascular disease. The aim of this study was to determinewhether MPV levels are higher in resistant hypertensive (RHTN) patients than in controlled hypertensive (CHTN) patients and healthynormotensive controls. Materials and Methods: 279 consecutive patients were included inthis study. Patients were divided into three groups: Resistant hypertension patient group [n=78; mean age 56.8±9.8; 42 males (53.8%)];controlled hypertension patient group [n=121; mean age 54.1±9.6;49 males (40.5%)]; and normotensive control group [n=80; mean age49.8±8.5; 34 males (42.5%)]. Physical examination, laboratory work- up, and 24-hour ambulatory blood pressure measurement (ABPM)were performed in all participants. Results: The mean platelet volume levels were significantly higher inRHTN group than in the CHTN and normotensive groups (p

Özet

Amaç: Dirençli hipertansif hastalar kardiyovaskiler olaylar açısındanyüksek risk altındadır. Ortalama trombosit hacmi (MPV) trobosit aktivasyonununu gösteren biomarker olarak kabul edilmiştir ve kardiovasküler risk artışının göstergelerindendir. Çalışmamızda dirençlihipertansif (RHTN) hastalarda kontrollü hipertansif (CHTN) ve normotansif hastalara göre ortalama trombosit hacminin artış gösteripgöstermediğinin değerlendirilmesi amaçlanmıştır. Gereç ve Yöntem: Çalışmamızda toplamda 279 hasta alınmış olup üçgruba ayrılmıştır. Bu gruplar dirençli hipertansif grup [n=78; ortalamayaş 56,8±9,8; 42 erkek cinsiyet oranı (%53,8)]; kontrollü hipertansifgrup [n=121; ortalama yaş 54,1±9,6; 49 erkek cinsiyeti oranı (%40,5)];normotensif control grup [n=80; ortalama yaş 49,8±8,5; 34 erkek cinsi- yet oranı (%42,5)] olarak tanımlanmıştır. Bütün hastalara fizik muayene,laboratuvar tetkikleri,ambulatuar kan basınç (ABPM) takibi yapılmıştır.Bulgular: Dirençli hipertansif grupta ortalama trombosit hacmikontrollü hipertansif ve normotansif gruba göre istatistiksel olarakanlamlı olarak yüksek saptanmıştır (p

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Cite This Article

BUTURAK, A., GUL, M., AKKAYA, E., UYGUR, B., YAZAN, S., AKGUL, O., EKSİK, A., PUSUROGLU, H., ERTURK, M., SURGİT, O. (2022). Dirençli Hipertansif, Kontrollü Hipertansif ve Normotansif Hastalarda Ortalama Trombosit Hacminin Değerlendirilmesi. Eurasian Journal of Medicine, Cilt: 47 - Sayı: 2, 79–84. https://ajindex.com/articles/509421

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