Journals / Eurasian Journal of Medicine / 2012 / Cilt: 44 - Sayı: 3

Sekelle sonuçlanan yaygın santral pons, bulbus ve talamik myelinolisis

Wide central pontine, bulbar and thalamic myelinolysis with sequela

Pages
179–181
Publication Date
2022-10-18
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

She delivered a normal child.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Although cases of hyponatremia during pregnancy have been de-scribed, it has rarely been possible to show demyelination lesions incentral pons, bulbus as well as thalamus, by imaging techniques.
📊
Key Findings & Data:In thesecond day of hospitalization, probably as a result of expansion ofmyelinolysis, she was intubated and received mechanical ventilatordue to bradypnea and a GCS scale of E1M4V2.
💡
Conclusion & Impact:She delivered a normal child.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Although cases of hyponatremia during pregnancy have been de-scribed, it has rarely been possible to show demyelination lesions incentral pons, bulbus as well as thalamus, by imaging techniques. Wereport a case that developed extensive myelinolysis due to the “rapid”correction of hyponatremia as a result of hyperemesis gravidarum.Magnetic resonance imaging showed bilaterally symmetric hyper-intense areas in the thalamus and cerebral crus and symmetric hy-perintense area in the central pons, with sparing of the rim. In thesecond day of hospitalization, probably as a result of expansion ofmyelinolysis, she was intubated and received mechanical ventilatordue to bradypnea and a GCS scale of E1M4V2. She was extubatedin 11th day of hospitalization and physical therapy was started. Shewas discharged in 30th day of hospitalization with a GCS of 15. Butshe was tetraparetic (2/5). In the 3rd month of follow up, her quadri-paresis improved to paraparesis in lower extremities (3/5). Her followup examinations in the first year did not change although physicaltherapies go on. She delivered a normal child.

Özet

Gebelik sırasında hiponatremi vakaları tanımlanmasına rağmen görüntüleme teknikleriyle talamusta olduğu kadar bulbus ve ponsun merkezindeki demiyelinizan lezyonlar nadiren görülebilmektedir.Hiperemesis gravidaruma bağlı oluşan hiponatreminin hızlı düzeltilmesiyle oluşan geniş miyelinolisis vakasını sunmak istedik. Manyetikrezonans görüntülemede ponsun merkezinde kenarları düzgün olansimetrik hiperintens, serebral krus ve talamusta iki taraflı simetrikhiperintens alanlar görülmektedir. Hastanın hastaneye yatırılışınınikinci gününde tahminen miyelinolisis alanlarının genişlemesiyleGKS 7 (E1M4V2), bradipnesi oldu ve hasta entübe edildi. Hastaneyeyatışının 11. gününde ekstübe edildi ve fizik tedavi başlandı. Hasta30. günde GKS:15 olarak taburcu edildi. Fakat hasta tetraparazikti(2/5). Üç ay sonra hastanın quadriparazisi bir miktar düzelerek altekstremitelerde paraparazisi (3/5) geriledi. Bir yıl boyunca almış olduğu fizik tedaviye rağmen değişiklik gözlenmedi. Hasta normal bir çocuk doğurdu.

🔖

Cite This Article

OZDEMİR, G., EMET, M., UZKESER, M., BAYRAMOGLU, A., AKOZ, A. (2022). Sekelle sonuçlanan yaygın santral pons, bulbus ve talamik myelinolisis. Eurasian Journal of Medicine, Cilt: 44 - Sayı: 3, 179–181. https://ajindex.com/articles/509234

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (4)

  1. Fairweather DV. Nausea and vomiting in pregnancy. Am J Obstet Gynecol 1968; 102: 135-75
  2. Verberg MF, Gillott DJ, Al-Fardan N, Grudzinskas JG. Hyperemesis gravidarum, a literature review. Hum Reprod Update 2005; 11: 527-39. [CrossRef] 3. Burneo J, Vizcarra D, Miranda H. Central pontine myelinolysis and pregnancy: a case report and review of literature. Rev Neurol 2000; 30: 1036-40
  3. Sonkusare S. The clinical management of hyperemesis gravidarum. Arch Gynecol Obstet 2011; 283: 1183-92. [CrossRef] 5. Sterns RH, Cappuccio JD, Silver SM, Cohen EP. Neurologic sequelae after treatment of severe hyponatremia: a multicenter perspective. J Am Soc Nephrol 1994; 4: 1522-30
  4. Sterns RH, Nigwekar SU, Hix JK. The treatment of hyponatremia. Semin Nephrol 2009; 29: 282-99. [CrossRef] 7. Norenberg MD. Central pontine myelinolysis: historical and mechanistic considerations. Metab Brain Dis 2010; 25: 97-106. [CrossRef] 8. Odier C, Nguyen DK, Panisset M. Central pontine and extrapontine myelinolysis: from epileptic and other manifestations to cognitive prognosis. J Neurol 2010; 257: 1176-80. [CrossRef] 9. Wakui H, Nishimura S, Watahiki Y, Endo Y, Nakamoto Y, Miura AB. Dramatic recovery from neurological deficits in a patient with central pontine myelinolysis following severe hyponatremia. Jpn J Med 1991; 30: 281-4. [CrossRef] 10. Hegde AN, Mohan S, Lath N, Lim CC. Differential diagnosis for bilateral abnormalities of the basal ganglia and thalamus. Radiographics 2011; 31: 5-30. [CrossRef]