Journals / Eurasian Journal of Medicine / 2012 / Cilt: 44 - Sayı: 3

Kronik obstrüktif akciğer hastalığında helicobacter pylori enfeksiyonu

Helicobacter pylori infections in chronic obstructive pulmonary disease

Pages
144–148
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: The presence of H. pylori infection in COPD patients affects pulmonary functions, but the effects of H. pylori infection on the respiratory system and COPD are not clear.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: We aimed to investigate the prevalence of Helicobacterpylori (H. pylori) in patients with chronic obstructive pulmonary disease (COPD) using the C-14 urea-breath test (C14UBT) and to determine whether there is an association between H. pylori infection andthe severity of COPD.
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Key Findings & Data:This is the first report in the literature of the useof C14UBT to investigate the prevalence of H. pylori in patients withCOPD.Materials and Methods: Fifty subjects with COPD (38 males and 12 females, aged 61±10 years) and 20 control subjects (10 males and 10 females, aged 55±11 years) were evaluated.
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Conclusion & Impact:Conclusion: The presence of H. pylori infection in COPD patients affects pulmonary functions, but the effects of H. pylori infection on the respiratory system and COPD are not clear.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: We aimed to investigate the prevalence of Helicobacterpylori (H. pylori) in patients with chronic obstructive pulmonary disease (COPD) using the C-14 urea-breath test (C14UBT) and to determine whether there is an association between H. pylori infection andthe severity of COPD. This is the first report in the literature of the useof C14UBT to investigate the prevalence of H. pylori in patients withCOPD.Materials and Methods: Fifty subjects with COPD (38 males and 12 females, aged 61±10 years) and 20 control subjects (10 males and 10 females, aged 55±11 years) were evaluated. C14UBT was used to determine H. pylori infection. Results: The prevalences of H. pylori infection in subjects with COPD and in controls were 72% and 65%, respectively (p=0.56). Forced expiratory volume in one second (FEV1) and forced vital capacity (FVC) values were significantly higher in the H. pylori-infected subjects with COPD than in the uninfected subjects (p=0.008 and p=0.006, respectively). Conclusion: The presence of H. pylori infection in COPD patients affects pulmonary functions, but the effects of H. pylori infection on the respiratory system and COPD are not clear.

Özet

Amaç: Bu çalışmada kronik obstrüktif akciğer hastalığı (KOAH) bulunan hastalarda C-14 üre-nefes testi (C14ÜNT) kullanarak Helicobacterpylori (H. pylori) prevalansını ve H. pylori enfeksiyonu ile KOAH şiddeti arasında bir ilişki olup olmadığını araştırmayı hedefledik. Bu, KOAH hastalarında H. pylori prevalansını araştırmak için C14ÜNT’nin kulla- nıldığı literatürdeki ilk çalışmadır. Gereç ve Yöntem: KOAH’lı 50 olgu (38 erkek ve 12 kadın, ortalama yaş: 61±10 yıl) ve 20 sağlıklı kontrol (10 erkek ve 10 kadın, ortalama yaş: 55±11 yıl) incelendi. H. pylori enfeksiyonunu saptamak için C14ÜBT kullanıldı. Bulgular: KOAH olguları ve kontroller için H. pylori enfeksiyonu prevalansı sırasıyla, %72 ve %65 olarak belirlendi (p=0.56). H. pylori enfeksiyonu bulunan KOAH olgularında, birinci saniyedeki zorlu ekspiratuvar volüm (FEV1) ve zorlu vital kapasite (FVC) değerleri, enfeksiyon bulunmayanlardan anlamlı olarak daha yüksek bulundu (sırasıyla, p=0.008 ve p=0.006). Sonuç: KOAH hastalarında H. pylori enfeksiyonu varlığı solunum fonksiyonlarını etkilemektedir, fakat H. pylori enfeksiyonunun solunum sistemi ve KOAH üzerine etkileri tam olarak aydınlatılmamıştır.

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Cite This Article

AKGUN, M., SAHİN, A., MERAL, M., GORGUNER, M., TABARU, A. (2022). Kronik obstrüktif akciğer hastalığında helicobacter pylori enfeksiyonu. Eurasian Journal of Medicine, Cilt: 44 - Sayı: 3, 144–148. https://ajindex.com/articles/509227

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