Journals / Eurasian Journal of Medicine / 2016 / Cilt: 48 - Sayı: 1

Hepatit B ve C Virüs Serolojisinde Yaşa Bağlı Değişim Hakkında Bir Çalışma

A Study on the Age-Related Changes in Hepatitis B and C Virus Serology

Pages
37–41
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Efforts should be continued to increase the level of awareness in the community for HBV and the importance of immunization

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: There are a limited number of studies on the seroprevalence of Hepatitis B virus (HBV) and Hepatitis C virus (HCV) infection in Turkey.
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Key Findings & Data:This study aimed to compare HBV and HCV seroprevalence rates before and after the implementation of national hepatitis B vaccination program (NHPVP) and to explore age-related changes in the seroprevalences.Materials and Methods: Results of Hepatitis B surface antigen (HBsAg), Hepatitis B virus surface antibody (antiHBs) and antiHCV tests performed during 2009 and 2010 in a state hospital laboratory were reviewed retrospectively.
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Conclusion & Impact:Efforts should be continued to increase the level of awareness in the community for HBV and the importance of immunization
🔬Design:Review & Systematic Survey
📍Scope:2009 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: There are a limited number of studies on the seroprevalence of Hepatitis B virus (HBV) and Hepatitis C virus (HCV) infection in Turkey. This study aimed to compare HBV and HCV seroprevalence rates before and after the implementation of national hepatitis B vaccination program (NHPVP) and to explore age-related changes in the seroprevalences.Materials and Methods: Results of Hepatitis B surface antigen (HBsAg), Hepatitis B virus surface antibody (antiHBs) and antiHCV tests performed during 2009 and 2010 in a state hospital laboratory were reviewed retrospectively. As NHPVP was started in 1998, 12 years of age and younger children were considered post- NHPVP period subjects.Results: A total of 3280 HBsAg, 2444 antiHBs and 3188 anti-HCV test results were reviewed, representing approximately 3% of the population of the city where the study was conducted. HBsAg, antiHBs and anti-HCV positivity were 3.2%, 36.12% and 0.97%, respectively. HBsAg and antiHBs positivity were higher among males (p0.05).Conclusion: Owing to the use of NHPVP, HBsAg seropositivity has decreased, and it is expected to decrease further in the next years with a wider implementation of the program. Efforts should be continued to increase the level of awareness in the community for HBV and the importance of immunization

Özet

Amaç: Türkiye'de Hepatit B virüs (HBV) ve Hepatit C virüs (HCV) enfeksiyonu seroprevelansının araştırıldığı çalışmalar sınırlı sayıdadır. Bu çalışmada ulusal hepatit B aşı programı (UHBAP) sonrası ve öncesi dönemde HBV ve HCV seroprevalansının karşılaştırılması ve bu seroprevalanstaki yaşa bağlı değişimin ortaya konulması amaçlanmıştır.Gereç ve Yöntem: Bir hizmet hastanesi laboratuarında 2009 ve 2010 yıllarında çalışılan Hepatit B yüzey antijeni (HBsAg), Hepatit B virüs yüzey antikoru (antiHBs) ve anti-HCV test sonuçları retrospektif olarak incelendi. UHBAP 1998 yılında başladığı için 12 yaş ve daha küçükler UHBAP sonrası dönem olarak kabul edildi.Bulgular: Çalışmanın yapıldığı il nüfusunun yaklaşık %3'üne tekabül eden 3280 HBsAg, 2444 antiHBs ve 3188 anti-HCV test sonucu değerlendirmeye alındı. HBsAg, antiHBs ve anti-HCV pozitifliği sırasıyla %3,2, %36,12 ve %0,97 bulundu. HBsAg ve antiHBs pozitifliği erkeklerde kadınlardan daha yüksekti (p0,05).Sonuç: UHBAP ile beraber HBsAg seropozitifliği azalmış ve programın daha geniş bir şekilde uygulanmasıyla önümüzdeki yıllarda daha da azalacağı beklenmektedir. HBV ile bağışıklamanın önemi hakkında toplumun farkındalık düzeyini artırıcı faaliyetlere devam edilmelidir

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Cite This Article

GUCLU, E., KARABAY, O., OGUTLU, A. (2022). Hepatit B ve C Virüs Serolojisinde Yaşa Bağlı Değişim Hakkında Bir Çalışma. Eurasian Journal of Medicine, Cilt: 48 - Sayı: 1, 37–41. https://ajindex.com/articles/509077

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