Journals / Eurasian Journal of Emergency Medicine / 2014 / Cilt: 13 - Sayı: 2

Investigation of the Relationship between Thyroid Hormone Levels and Mortality in Old Patients Hospitalized in an Internal Medicine Intensive Care Unit from the Emergency Service

Pages
71–74
Publication Date
2022-10-11
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

FT3 levels can be used as a prognostic indicator after more detailed studies are completed. (JAEM 2014; 13: 71-4)

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In our study, the purpose was to determine the relationship between thyroid hormones and mortality of patients over the age of 55 who were hos- pitalized in an intensive care unit from the emergency service.
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Key Findings & Data:After con- firmation from the patients and their relatives, we included 73 patients in our study: 48 (65.8%) males and 25 (34.2%) females.
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Conclusion & Impact:FT3 levels can be used as a prognostic indicator after more detailed studies are completed. (JAEM 2014; 13: 71-4)
🔬Design:Research Article
📍Scope:2014 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: In our study, the purpose was to determine the relationship between thyroid hormones and mortality of patients over the age of 55 who were hos- pitalized in an intensive care unit from the emergency service. Material and Methods: This study was planned as a prospective, randomized study, and patients hospitalized in an intensive care unit from the emergency medicine department were enrolled in this study following ethics committee approval. A standard data collection form was used to collect the data. After con- firmation from the patients and their relatives, we included 73 patients in our study: 48 (65.8%) males and 25 (34.2%) females. Blood samples were taken from each patient, and thyroid hormone levels were studied in our laboratory. The SPSS for Windows version 18 program was used for statistical analysis of the data. Chi-square test was used to compare categorical measures between the groups. Mann-Whitney U-test and t-test were used to compare quantitative measure- ments between the groups. The log-rank test was performed under Kaplan-Meier survival analysis to determine the relationship between the estimated lifetime and free T3 (fT3), free T4 (fT4), and thyroid-stimulating hormone (TSH). Results: There was no statistically significant difference in mean ages and genders of patients who died and survived. The mean duration of hospitalization in the deceased patient group was lower than in the surviving patient group, but there was no statistically significant difference between the groups. According to the Kaplan-Meier survival analysis, the patients with low or high levels of fT3 were found to have a shorter median life expectancy. No significant relationship was found between mortality and fT4 TSH. Conclusion: According to our study, increased or decreased levels of fT3 in patients over the age of 55 without known thyroid disease, hospitalized in an inten- sive care unit from the emergency department, showed increased mortality. This study will be useful for emergency medicine physicians to be able to predict the mortality of patients and contribute to more clinical experience. FT3 levels can be used as a prognostic indicator after more detailed studies are completed. (JAEM 2014; 13: 71-4)

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Cite This Article

TOPAL, M., AÇIKALIN, A., GÜLEN, M., TOPAL, Y., KARANLIK, M., AY, M. O., SEBE, A. (2022). Investigation of the Relationship between Thyroid Hormone Levels and Mortality in Old Patients Hospitalized in an Internal Medicine Intensive Care Unit from the Emergency Service. Eurasian Journal of Emergency Medicine, Cilt: 13 - Sayı: 2, 71–74. https://ajindex.com/articles/508236

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References (5)

  1. Tas A, Tetiker T, Beyazit Y, Celik H, Yesil Y. Thyroid hormone levels as a pre- dictor of mortality in intensive care patients: A comparative prospective study. Wien Klin Wochenschr 2012; 124: 154-9. [CrossRef] Fliers E, Alkemade A, Wiersinga WM. The hypothalamic-pituitary-thyroid axis in critical illness. Best Pract Res Clin Endocrinol Metab 2001; 15: 453-64. [CrossRef] Sandalci O, Molvalilar S, Azizlerli H, Alagol MF, Orhan Y, Tanakol R, et al. Endokrinoloji, Metabolizma ve Beslenme Hastalıkları 5. Bölüm Tiroid Hastalıkları 2001: 93-101. Burmeister LA. Reverse T3 does not raliably differentiate hypothyroid sick syndrome from euthyroid sick sendrome. Thyroid 1995; 5: 435-41. [CrossRef] Jirasakuldech B, Schussler GC, Yap MG. A charecteristic serpin cleavage product of thyroxine binding globulin appears in sepsis sera. J Clin En- dokrinol Metab 2000; 85: 3996-9. [CrossRef] İlicin G, Biberoglu K, Suleymanlar G, Unal S. Ic Hastaliklari 2. Baski 2003: 2167-75.
  2. Aulbert E, Steffens O. Serum ferritin-a tumor marker in malignant lym- phomas? Onkologie 1990; 13: 102-8. [CrossRef] Trivedi TH, Shejale SB, Yeolekar ME. Nosocomial pneumonia in medical intensive care unit. J Assoc Physicians India 2000; 48: 1070-3.
  3. Seferian EG, Afessa B. Adult intensive care unit use at the end of life: a popullation-based study. Mayo Clin Proc 2006; 81: 896-901. [CrossRef] Scott BH, Seifert FC, Grimson R, Glass PS. Octogenarians undergoing coro- nery artery bypass graft surgery: resource utilization, postoperative mortality and morbibity. J Cardiothorac Wasc Anesth 2005; 19: 583-8. [CrossRef] Ray DC, Drummond GB, Wilkinson E, Beckett GJ. Relationship of admis- sion thyroid function tests to outcome in critical illness. Anaesthesia 1995; 50: 1022-5. [CrossRef] Guyton AC, Hall JE. Textbook of Medical Physiology. 7th ed. Philadelphia: WB Saunders; 2001.p.1291-301. Ganong WF. Ganong Medical Physiology. 16th ed. New York: Mc- Graw-Hill; 2002.p.345-56.
  4. Fliers E, Alkemode A, Wiersinga WM. The hypothalamic-pituitery-thyroid axis in critical ilness. Best pract Res Clin Endokrinol Metab 2001; 15: 453- 64. [CrossRef] Van den Berge G. The neuroendocrine response to stres is a dynamic pro- cess. Clin Endocrinol Metab 2001; 15: 405-19. Felicetta JV. Endocrine changes with critical illness. Crit Care Clin 1987; 5: 855-69.
  5. Stathatos N, Leveton C, Burman KD. Wort of sky L. The controversy of the treatment of critically ill patients with thyroid hormone. Best Pract Res Clin Endocrinol Metab 2001; 15: 46