Diagnostic Value of Pentraxin-3 in Patients with Spontaneous Subarachnoid and Intracerebral Hemorrhage

Results: In the study, the levels of serum PTX3 measured at presentation and at the twelfth hour after presentation were found to be statistically and significantly different in the SAH group compared to the control group (p

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: In this study, the diagnostic and prognostic values of serum pentraxin-3 (PTX3) level were evaluated in spontaneous subarachnoid hemorrhage (SAH) and intracerebral hemorrhage (ICH) patients.

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Key Findings & Data:Materials and Methods: The study was conducted prospectively on patients in the emergency department between April 2014 and December 2015 at the Faculty of Medicine.

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Conclusion & Impact:Results: In the study, the levels of serum PTX3 measured at presentation and at the twelfth hour after presentation were found to be statistically and significantly different in the SAH group compared to the control group (p

🔬Design:Research Article

📍Scope:2014 Verileri

⚙️Variables:Domain Parameters

Abstract

Aim: In this study, the diagnostic and prognostic values of serum pentraxin-3 (PTX3) level were evaluated in spontaneous subarachnoid hemorrhage (SAH) and intracerebral hemorrhage (ICH) patients. Materials and Methods: The study was conducted prospectively on patients in the emergency department between April 2014 and December 2015 at the Faculty of Medicine. Patients who were older than 18 years, who presented to the emergency department with neurologic findings, and who were diagnosed with SAH and ICH pursuant to a computed tomography (CT) scan of the brain were included. PTX3 levels were evaluated in the blood samples collected at the time of presentation to hospital and at the twelfth hour after presentation. Results: In the study, the levels of serum PTX3 measured at presentation and at the twelfth hour after presentation were found to be statistically and significantly different in the SAH group compared to the control group (p

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Cite This Article

ÖREM, A., KATİPOĞLU, B., TATLI, Ö., AYGÜN, A., YAMAN, H., MENTEŞE, A., GÜNDÜZ, A., ÇAKMAK, V. A., GAZİOĞLU, G., ARGIN, C. E. (2022). Diagnostic Value of Pentraxin-3 in Patients with Spontaneous Subarachnoid and Intracerebral Hemorrhage. Eurasian Journal of Emergency Medicine, Cilt: 16 - Sayı: 3, 133–136. https://ajindex.com/articles/508109

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References (1)

Wolf PA, D'Agostino RB. Secular trends in stroke in the Framingham Study. Ann Epidemiol 1993; 3: 471-5. [CrossRef] 2. Zhang X, Xu Z, Zhou L, Chen Y, He M, Cheng L, et al. Plasma levels of Hsp70 and anti-Hsp70 antibody predict risk of acute coronary syndrome. Cell Stress Chaperones 2010; 15: 675-86. [CrossRef] 3. Manfredi AA, Rovere-Querini P, Bottazzi B, Garlanda C, Mantovani A. Pentraxins, humoral innate immunity and tissue injury. Curr Opin Immunol 2008; 20: 538-44. [CrossRef] 4. Epidemiology of aneurysmal subarachnoid hemorrhage in Australia and New Zealand: incidence and case fatality from the Australasian Cooperative Research on Subarachnoid Hemorrhage Study (ACROSS). Stroke 2000; 31: 1843-50. [CrossRef] 5. Pfohman M, Criddle LM. Epidemiology of intracranial aneurysm and subarachnoid hemorrhage. J Neurosci Nurs 2001; 33: 39-41. [CrossRef] 6. Edlow JA, Caplan LR. Avoiding pitfalls in the diagnosis of subarachnoid hemorrhage. N Engl J Med 2000; 342: 29-36. [CrossRef] 7. Sturgeon JD, Folsom AR, Longstreth WT Jr, Shahar E, Rosamond WD, Cushman M. Risk factors for intracerebral hemorrhage in a pooled prospective study. Stroke 2007; 38: 2718-25. [CrossRef] 8. Özdemir Ö, Özbabalık D, Özdemir G. İntraserebral hemoraji. Balkan S (Editör). Serebrovasküler Hastalıklar>da. 3.baskı. Ankara: Güneş kitabevi; 2009; 147-60. 9. Kassell NF, Torner JC, Haley EC Jr, Jane JA, Adams HP, Kongable GL. The international Cooperatıve Study on the Timing of Aneurysm Surgery Part 1: Overall management results. J Neurosurg 1990; 73: 18-36. [CrossRef ] 10. Ogilvy CS, Carter BS. Grading system to predict outcome for surgical management of intracranial a proposed comprehensive aneurysms. Neurosurgery 1998; 43: 572-86. 11. Dietrich HH, Dacey RC Jr. Molecular keys to the problems of cerebral vasospasm. Neurosurgery 2000; 46: 517-27. [CrossRef] 12. Hemphill JC 3rd, Greenberg SM, Anderson CS, Becker K, Bendok BR, Cushman M, et al., Guidelines for the Management of Spontaneous Intracerebral Hemorrhage: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke 2015; 46: 2032-60. [CrossRef] 13. Garlanda C, Bottazzi B, Bastone A, Mantovani A. Pentraxins at the crossroads between innate immunity, inflammation, matrix deposition, and female fertility. Annu Rev Immunol 2005; 23: 337-66. [CrossRef] 14. Cook DN, Pisetsky DS, Schwartz DA. Toll-like receptors in the pathogenesis of human disease. Nat Immunol 2004; 5: 975-9. [CrossRef] 15. Luc