Journals / Eurasian Journal of Emergency Medicine / 2019 / Cilt: 18 - Sayı: 1

A Randomized Double-Blind Study: Evulation of Comparing Intravenous Fentanyl with Intravenous Tramadol Administered to Patients with Pain Control Due to Urinary Stone Disease

Pages
48–54
Publication Date
2022-10-11
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

While 16 patients responded to the treatment in the fentanyl group, 18 patients responded to the treatment in the tramadol group.Conclusion: Our study concluded that both drugs are effective on renal colic pain and they do not have a significant advantage over each other.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: The aim of our study is to compare the efficiency of fentanyl and tramadol as analgesics in renal colic patients.Materials and Methods: Our research is a prospective, randomized, double-blind study.
📊
Key Findings & Data:The outcomes of the analgesic efficacy in our study were the difference between VAS 0-VAS 60 values and the score less than 4 in VAS 60.Results: A total of 912 renal colic patients were admitted during the study period.
💡
Conclusion & Impact:While 16 patients responded to the treatment in the fentanyl group, 18 patients responded to the treatment in the tramadol group.Conclusion: Our study concluded that both drugs are effective on renal colic pain and they do not have a significant advantage over each other.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: The aim of our study is to compare the efficiency of fentanyl and tramadol as analgesics in renal colic patients.Materials and Methods: Our research is a prospective, randomized, double-blind study. We administered intravenous (i.v.) non-steroid anti-inflammatory drugs as first line treatment. Then, “i.v. fentanyl” and “i.v. tramadol” were administered to the patients whose pain did not relieve. The outcomes of the analgesic efficacy in our study were the difference between VAS 0-VAS 60 values and the score less than 4 in VAS 60.Results: A total of 912 renal colic patients were admitted during the study period. When the exclusion criteria were applied, the study was completed with 143 patients. The difference between VAS 0 and VAS 60 values-which is the primary outcome in the evaluation of analgesic efficiency in our study is 6.11±2.49 in fentanyl and 5.94±2.40 in tramadol group. While 16 patients responded to the treatment in the fentanyl group, 18 patients responded to the treatment in the tramadol group.Conclusion: Our study concluded that both drugs are effective on renal colic pain and they do not have a significant advantage over each other.

🔖

Cite This Article

KOÇAK, A. O. (2022). A Randomized Double-Blind Study: Evulation of Comparing Intravenous Fentanyl with Intravenous Tramadol Administered to Patients with Pain Control Due to Urinary Stone Disease. Eurasian Journal of Emergency Medicine, Cilt: 18 - Sayı: 1, 48–54. https://ajindex.com/articles/508007

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. Varrassi G, Hanna M, Macheras G, Montero A, Montes Perez A, Meissner W, et al. Multimodal analgesia in moderate-to-severe pain: a role for a new fixed combination of dexketoprofen and tramadol. Curr Med Res Opin. 2017;33(6):1165-73.
  2. Heidenreich A, Desgrandschamps F, Terrier F. Modern approach of diagnosis and management of acute flank pain: review of all imaging modalities. Eur Urol. 2002;41(4):351-62.
  3. Golzari SE, Soleimanpour H, Rahmani F, Zamani Mehr N, Safari S, Heshmat Y, et al. Therapeutic approaches for renal colic in the emergency department: a review article. Anesth Pain Med. 2014;4(1):e16222. Engeler DS, Schmid S, Schmid HP. The ideal analgesic treatment for acute renal colic-theory and practice. Scand J Urol Nephrol. 2008;42(2):137-42.
  4. Skolarikos A, Straub M, Knoll T, Sarica K, Seitz C, Petrik A, et al. Metabolic evaluation and recurrence prevention for urinary stone patients: EAU guidelines. Eur Urol. 2015;67(4):750-63.
  5. Sanchez-Carpena J, Dominguez-Hervella F, Garcia I, Gene E, Bugarin R, Martin A, et al. Comparison of intravenous dexketoprofen and dipyrone in acute renal colic. Eur J Clin Pharmacol. 2007;63:751-60.
  6. Imamoglu M, Aygun A, Bekar O, Erdem E, Cicek M, Tatli O, et al. A retrospective analysis of nebulized versus intravenous fentanyl for renal colic. Am J Emerg Med. 2017;35:757-63.
  7. Micali S, Grande M, Sighinolfi MC, De Carne C, De Stefani S, Bianchi G. Medical therapy of urolithiasis. J Endourol. 2006;20:841-7.
  8. Pathan SA, Mitra B, Cameron PA. A Systematic Review and Meta-analysis Comparing the Efficacy of Nonsteroidal Anti-inflammatory Drugs, Opioids, and Paracetamol in the Treatment of Acute Renal Colic. Eur Urol. 2018;73:583-95. Guidelines on urolithiasis. European Association of Urology [Internet]. [cited July 1, 2018]. Available from: http://uroweb.org/guideline/urolithiasis/.
  9. Holdgate A, Pollock T. Nonsteroidal anti-inflammatory drugs (NSAIDs) versus opioids for acute renal colic. Cochrane Database Syst Rev. 2005:CD004137. Phillips E, Kieley S, Johnson EB, Monga M. Emergency room management of ureteral calculi: current practices. J Endourol. 2009;23:1021-4.
  10. Bektas F, Eken C, Karadeniz O, Goksu E, Cubuk M, Cete Y. Intravenous paracetamol or morphine for the treatment of renal colic: a randomized, placebo-controlled trial. Ann Emerg Med. 2009;54:568-74.
  11. Cordell WH, Wright SW, Wolfson AB, Timerding BL, Maneatis TJ, Lewis RH, et al. Comparison of intravenous ketorolac, meperidine, and both (balanced analgesia) for renal colic. Ann Eme