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Journals / Eurasian Journal of Emergency Medicine / 2022 / Cilt: 21 - Sayı: 1

QTc, Tp-e Interval and Tp-e/QTc Ratio Changes in Hypoxia Due to Hypertensive Pulmonary Edema-Case Control Study

Hasan KOCA
Fadime KOCA
Akkan AVCI
Müge GÜLEN
Begüm Şeyda AVCI
Salim SATARİ
Ferhat İÇME
Önder YEŞİLOĞLU
Serdar BİRİCİK
Pages
14–19
Publication Date
2022-10-11
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

QTc interval, Tp-e interval and Tpe/QTc values were found to be significantly higher in hypoxia caused by hypertensive pulmonary edema (p

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: As far as we have investigated, although there are researches on QT and QTc interval, there are no studies evaluating T wave peak-toend distance (Tp-e interval), the ratio of Tp-e to QT and QTc used in the evaluation of cardiac arrhythmia risk and ventricular repolarization changes in patients with hypoxia due to hypertensive pulmonary edema.
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Key Findings & Data:All patients underwent 12-lead electrocardiography (ECG).
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Conclusion & Impact:QTc interval, Tp-e interval and Tpe/QTc values were found to be significantly higher in hypoxia caused by hypertensive pulmonary edema (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: As far as we have investigated, although there are researches on QT and QTc interval, there are no studies evaluating T wave peak-toend distance (Tp-e interval), the ratio of Tp-e to QT and QTc used in the evaluation of cardiac arrhythmia risk and ventricular repolarization changes in patients with hypoxia due to hypertensive pulmonary edema. Therefore, in this study was aimed to study whether there is a change in Tp-e interval, the ratio of Tp-e to QTc in hypoxia due to hypertensive pulmonary edema. Materials and Methods: Forty patients diagnosed with hypertensive pulmonary edema in the emergency room were included in the study retrospectively. Forty patients with similar age and gender distribution were included in the study as a control group. All patients underwent 12-lead electrocardiography (ECG). In addition to the routine measurements, Tp-e interval, the ratio of Tp-e to QTc were measured in ECG. Study data were grouped as patients with and without hypoxia Results: Mean age for patients was 68.60±15.25. QTc interval, Tp-e interval and Tpe/QTc values were found to be significantly higher in hypoxia caused by hypertensive pulmonary edema (p

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Cite This Article

KOCA, H., KOCA, F., AVCI, A., GÜLEN, M., AVCI, B. Ş., SATARİ, S., İÇME, F., YEŞİLOĞLU, Ö., BİRİCİK, S. (2022). QTc, Tp-e Interval and Tp-e/QTc Ratio Changes in Hypoxia Due to Hypertensive Pulmonary Edema-Case Control Study. Eurasian Journal of Emergency Medicine, Cilt: 21 - Sayı: 1, 14–19. https://ajindex.com/articles/507563

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References (12)

  1. Sanjay KG, John CP, Abdel-Mohsen N, Karen F, Dalane WK, Kevin MR, et al. The pathogenesis of acute pulmonary edema associated with hypertension. N Engl J Med. 2001;344:17-22
  2. Hool LC. Acute hypoxia differentially regulates K+ channels. Implications with respect to cardiac arrhythmia. Eur Biophys J. 2005;34:369-76
  3. Frédéric R, Claire R, Vincent P, David D, Frédéric C, Martin G, et. al. Effect of acute hypoxia on QT rate dependence and corrected QT interval in healthy subjects. Am J Cardiol. 2003;91:916-9
  4. Fabio P, Sara C, Susanna M, Fabio C. Effect of acute hypoxia on QTc interval in respiratory patients undergoing fitness to fly tests. Thorax. 2011;66:725-6
  5. Kongstad O, Xia Y, Liang Y, Hertevig E, Ljungström E, Olsson B, et al. Epicardial and endocardial dispersion of ventricular repolarization. A study of monophasic action potential mapping in healthy pigs. Scand Cardiovasc J. 2005;39:342-7
  6. Porthan K, Viitasalo M, Toivonen L, Havulinna AS, Tikkanen JT, Vaananen H, et al. Predictive value of electrocardiographic T Wave morphology parameters and T-Wave peak to T-Wave end interval for sudden cardiac death in the general population clinical perspective. Cir Arrhythm Electrophysiol. 2013;6:690-6
  7. Xia Y, Liang Y, Kongstad O, Holm M, Olsson B, Yuan S. Tpeak-Tend interval as an index of global dispersion of ventricular repolarization: evaluations using monophasic action potential mapping of the epi and endocardium in swine. J Interv Card Electrophysiol. 2005;14:79-87
  8. Chua KCM, Rusinaru C, Reinier K, Uy-Evanado A, Chugh H, Gunson Karen, et al. Tpeak-to-Tend interval corrected for heart rate: A more precise measure of increased sudden death risk? Heart Rhythm. 2016;13:2181-5
  9. Gupta P, Patel C, Patel H, Narayanaswamy S, Malhotra B, Green JT, et al. T(p-e)/ QT ratio as an index of arrhythmogenesis. J Electrocardiol. 2008;41:567-74
  10. Smetana P, Schmidt A, Zabel M, Hnatkova K, Franz M, Huber K, et al. Assessment of repolarization heterogeneity for prediction of mortality in cardiovascular disease: peak to the end of the T wave interval and nondipolar repolarization components. J Electrocardiol. 2011:44:301-8
  11. Szymanski FM, Karpinski G, Platek A, Puchalski B, Filipak KJ. Long QT interval in a patient after out-of-hospital cardiac arrest with hypocalcaemia, undergoing therapeutic hypothermia. Am J Emerg Med. 2013;31:1722.e1-3
  12. Murray JF. Pulmonary edema: pathophysiology and diagnosis. Int J Tuberc Lung Dis. 2011;15:155-60