Journals / European Journal of Rheumatology / 2014 / Cilt: 1 - Sayı: 1

Kalp hızı değişkenliği ile belirlenen akrosiyanozda otonom fonksiyonlar

Autonomic functions in acrocyanosis assessed by heart rate variability

Pages
18–20
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Also, these results suggest that acrocyanosis is not a localised disorder; on the contrary, it is associated with various abnormalities of the systemic autonomic nervous system

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: To evaluate the autonomic activity of patients with acrocyanosis by using heart rate variability indices.
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Key Findings & Data:Material and Methods: The study group consisted of 24 patients with acrocyanosis and the control group contained 22 sex- and age-matched healthy subjects.
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Conclusion & Impact:Also, these results suggest that acrocyanosis is not a localised disorder; on the contrary, it is associated with various abnormalities of the systemic autonomic nervous system
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: To evaluate the autonomic activity of patients with acrocyanosis by using heart rate variability indices. Material and Methods: The study group consisted of 24 patients with acrocyanosis and the control group contained 22 sex- and age-matched healthy subjects. All subjects underwent 24-hour Holter monitoring. Among the heart rate variability (HRV) parameters, time-domain and frequency-domain indices were analysed.Results: The time-domain indices of HRV indicating global autonomic functions were found to be increased, and indices indicating parasympathetic activity showed a significant decrease in the patient group. Power-spectral analysis of HRV revealed that the low frequency and high frequency power were higher in the patient group than in controls. However, the ratio of Low Frequency/High Frequency was found to be lower in the patient group than in controls.Conclusion: In acrocyanosis, both sympathetic and parasympathetic systems seem to be disrupted. Therefore, we may conclude that acrocyanosis may be resulted of systemic autonomic imbalance rather than pure sympathetic over-activation. Also, these results suggest that acrocyanosis is not a localised disorder; on the contrary, it is associated with various abnormalities of the systemic autonomic nervous system

Özet

Amaç: Kalp hızı değişkenliği indeksleri kullanarak akrosiyanoz hastalarının otonom aktivitelerini değerlendirmek. Materyal ve Metot: Çalışma grubu akrosiyanozu olan 24 hastadan ve kontrol grubu 22 cinsiyet ve yaş eşleştirilmiş sağlıklı bireylerden oluşmaktaydı. Tüm bireyler 24 saat Holter ile izlendi. Kalp hızı değişkenliği (KHD) parametreleri arasında zaman ve frekans alan indeksleri analiz edildi. Bulgular: Global otonom fonksiyonlarını gösteren KHD zaman alan indeksleri artmış olarak bulundu ve parasempatik aktiviteleri gösteren indeksler hasta grubunda anlamlı düşüş gösterdi. KHD'nin güç-spektrum analizi, düşük frekans ve yüksek frekans gücünün hasta grubunda kontrol grubuna göre daha yüksek olduğunu gösterdi. Ancak, düşük frekans/yüksek frekans oranı hasta grubunda kontrol grubuna göre daha düşük bulundu. Sonuç: Akrosiyanozda hem sempatik hem de parasempatik sistemler bozulmuş gibi görünmektedir. Bu yüzden, akrosiyanozun salt sempatik aşırı aktivasyonundan değil sistemik otonom imbalansın bir sonucu olduğuna varabiliriz. Ayrıca, bu sonuçlar akrosiyanozun lokalize bir bozukluk olmadığını, aksine sistemik otonom sinir sisteminin çeşitli anormallikleri ile ilişkili olduğunu gösterir.

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Cite This Article

ÇINAR, M., YILMAZ, S., ÖZ, B. S., ŞİMŞEK, İ., PAY, S., DİNÇ, A., ERDEM, H., BAYSAN, O., YOKUŞOĞLU, M. (2022). Kalp hızı değişkenliği ile belirlenen akrosiyanozda otonom fonksiyonlar. European Journal of Rheumatology, Cilt: 1 - Sayı: 1, 18–20. https://ajindex.com/articles/505601

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