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Journals / Erciyes Üniversitesi Veteriner Fakültesi Dergisi / 2022 / Cilt: 19 - Sayı: 2

Sepsis Pathogenesis, Diagnosis and Treatment. Oxidative Stress in Sepsis and Sepsis Inflammation Relation. Experimental Models in Sepsis

Sepsis Patogenezi, Tanı ve Tedavisi Sepsiste Oksidatif Stres ve Sepsis İnflamasyon İlişkisi, Sepsiste Deneysel Modeller

Esra Nur ÜVENÇ
Feride KOÇ
Pages
145–151
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In addition, it was aimed to give information about the relationship between systemic inflammatory response and sepsis, the causes of oxidative stress, its formation and connection with sepsis, and experimental sepsis models in pharmacology.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Sepsis is an important systemic response with high mortality rates in both human medicine and veterinary medicine.
📊
Key Findings & Data:In this seminar, Pathogenesis, etiology, epidemiology, diagnosis, and treatment of sepsis are mentioned.
💡
Conclusion & Impact:In addition, it was aimed to give information about the relationship between systemic inflammatory response and sepsis, the causes of oxidative stress, its formation and connection with sepsis, and experimental sepsis models in pharmacology.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:İnflamasyon · oksidatif stres · sepsis

Abstract

Sepsis is an important systemic response with high mortality rates in both human medicine and veterinary medicine. In this seminar, Pathogenesis, etiology, epidemiology, diagnosis, and treatment of sepsis are mentioned. In addition, it was aimed to give information about the relationship between systemic inflammatory response and sepsis, the causes of oxidative stress, its formation and connection with sepsis, and experimental sepsis models in pharmacology.

Özet

Sepsis hem beşerî hekimlik hem de veteriner hekimlikte yüksek ölüm oranları ile seyreden önemli bir sistemik ce-vaptır. Bu derleme makalede; sepsisin patogenezi, etiyolojisi, epidemiyolojisi, teşhis ve tedavi yöntemlerinden bahsedil-mektedir. Bunun yanında, sistemik inflamatuvar cevap ile sepsis ilişkisi, oksidatif stresin sebepleri, oluşumu ve sepsisle olan bağlantısı ve farmakolojide deneysel olarak uygulanan sepsis modelleri hakkında bilgi verilmesi amaçlanmıştır.

🔖

Cite This Article

ÜVENÇ, E. N., KOÇ, F. (2022). Sepsis Pathogenesis, Diagnosis and Treatment. Oxidative Stress in Sepsis and Sepsis Inflammation Relation. Experimental Models in Sepsis. Erciyes Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 19 - Sayı: 2, 145–151. https://ajindex.com/articles/503633

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References (12)

  1. Akyıldız Ö, Beşli Y, Kocagöz AS. Yoğun bakım ün-itesinde bakteriyemi tanısı ile takip edilen has-taların değerlendirilmesi. Cukurova Med J 2019; 44(1): 521-8.
  2. Akyüz E, Naseri A, Erkılıç EE, Makav M, Uzlu E, Kırmızıgül AH, Gökçe G. Neonatal buzağı ishalleri ve sepsis. KAUFBED 2017; 10(2): 181-91.
  3. Angus DC, Van Der Poll T. Severe sepsis and septic shock. N Engl J Med 2013; 369: 840-51. Aruoma OI. Free radicals, oxidative stress, and anti-oxidants in human health and disease. J Am Oil Chem Soc 1998; 75(2): 199-212. Aygün G. Sepsis ve septik şok. Akılcı antibiyotik kullanımı ve erişkinlerde toplumdan edinilmiş en-fenksiyonlar. Sempozyum Dizisi No:312002; 131-40.
  4. Bone RC, Balk RA, Cerra FB, Dellinder RP, Fein AM, Knaus WA, Schein RMH, Sibbald WJ. Definitions for sepsis and organa failure and guidelines for the use of innovative therapies in sepsis. Chest 1992; 101: 1644-55.
  5. Bone RC, Grodzin CJ, Balk RA. Sepsis: A new hy-pothesis for pathogenesis of the disease process. chest 1997; 112: 235-43.
  6. Borrelli E, Roux‐Lombard P, Grau GE, Girardin E, Ricou B, Dayer J, Suter PM. Plasma concentra-tions of cytokines, their soluble receptors, and antioxidant vitamins can predict the development of multiple organ failure in patients at risk. Crit Care Med 1996; 24: 392-7.
  7. Cecconi M, DeBacker D, Antonelli M, Beale R, Bak-ker B, Hofer C, Jaeschke R, Mebazaa A, Pinsky MR, Teboul JL, Vincent JL, Rhodes A. Consen-sus on circulatory shock and hemodynamic moni-toring. Task force of the European Society of In-tensive Care Medicine. Intensive Care Med 2014; 40: 1795-815. Çaylak E. Hayvan ve bitkilerde oksidatif stres ile anti-oksidanlar. Tıp Araştırmaları Dergisi 2011; 9(1): 73-83.
  8. Dellinger RP, Levy MM, Rhodes A, Annane D, Ger-lach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, Osborn TM. Surviving sepsis campaign: International guidelines for management of severe sepsis and septic shock. Crit Care Med 2013; 41: 580-637.
  9. Dündar Y, Aslan R. Oksidan-antioksidan denge ve korunmasında vitaminlerin rolü. Hayvancılık Araştırma Dergisi 1999; 1(2): 32-9.
  10. Ercan N, Fidancı UR. Piyodermalı köpeklerde idrarda 8-hidroksi-2’ deoksiguanozin (8-OHdG) düzeyleri. Ankara Univ Vet Fak Dergisi 2012; 59: 163-8.
  11. Freeman BA., Crapo JD. Biology of disease: Free radicals and tissue injury. Lab Invest 1982; 47: 412-6. Gutteridge JMC. Lipid peroxidation and antioxidants as biomarkers of tissue damage. Clin Chem 1995; 41: 1819-28.
  12. Gürkan Ö, Çobanlı B. Sepsis ve septik şok. Ankara Üniversitesi Tıp