Journals / Erciyes Tıp Dergisi / 1997 / Cilt: 19 - Sayı: 1

Yenidoğan sistemik kandidiazisinde flukonazol tedavisi

Fluconazole therapy in neonatal systemic candidiasis

Pages
37–42
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We conclude that infants with neonatal systemic candidiasis can successfully be treated with fluconazole.

📌 3 Key Takeaways

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Objective & Hypothesis:Seven infants with a mean birth weight of 1.87± 0.18 kg and a mean gestational age of 34 1.0 weeks developed systemic candidiasis.
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Key Findings & Data:All these infants had required prolonged peripheral intravascular catheterization, broad-spectrum antibiotic therapy and hyperalimentation prior to the development of systemic candidiasis.
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Conclusion & Impact:We conclude that infants with neonatal systemic candidiasis can successfully be treated with fluconazole.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Seven infants with a mean birth weight of 1.87± 0.18 kg and a mean gestational age of 34 1.0 weeks developed systemic candidiasis. All these infants had required prolonged peripheral intravascular catheterization, broad-spectrum antibiotic therapy and hyperalimentation prior to the development of systemic candidiasis. Candida species were isolated from the blood of all infants. The most frequently observed clinical features were abdominal distention, temperature instability and hypotonia. Intravenous fluconazole eradicated the systemic infection in five of seven infants without any side effects. We conclude that infants with neonatal systemic candidiasis can successfully be treated with fluconazole.

Özet

: Ortalama doğum ağırlığı 1.87±0.18 kg ve ortalama gestasyonel yaşı 34±1.0 hafta olan yedi yenidoğanda sistemik kandidiazis gelişti. Tüm bu olgulara sistemik kandidiazis gelişmeden önce uzun süreli periferik intravaskuler kateterizasyon, geniş spektrumlu antibiotik tedavisi ve hiperalimantasyon uygulanmıştı. Tüm olguların kan kültürlerinde Candida üretildi. En sık gözlenen klinik bulgular; abdominal distansiyon, ısı regulasyonunda bozukluk ve metabolik asidoz idi. întravenöz flukonazol, hiç bir yan etki görülmeksizin, yedi olgunun beşinde sistemik enfeksiyonu eradike etti. Neonatal kandidiazisli olgular flukonazol ile başarılı bir şekilde tedavi edilebilir.

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Cite This Article

OKUTAN, V., SARICI, Ü., ALPAY, F., AKIN, R., GÖKÇAY, E. (2022). Yenidoğan sistemik kandidiazisinde flukonazol tedavisi. Erciyes Tıp Dergisi, Cilt: 19 - Sayı: 1, 37–42. https://ajindex.com/articles/503059

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