Journals / Erciyes Tıp Dergisi / 1999 / Cilt: 21 - Sayı: 3

Polinöropati ile birlikte seyreden izole cilt vaskülü

Isolated cutaneous vasculitis associated with polyneuroparhy

Pages
165–170
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In the current study we report a very typical patient with isolated cutaneous vasculitis associated with polyneuropathy presumably due to streptomycine injection.

📌 3 Key Takeaways

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Objective & Hypothesis:A 26 year-old- woman with neuropathy developed erythema, purpura, bullous lesions and subsequent ulcers on the anterior aspects of right leg and left ankle.
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Key Findings & Data:Pathological examination of punch biopsy specimens taken from ulcerative lesions manifested leukocytoclastic vasculitis.
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Conclusion & Impact:In the current study we report a very typical patient with isolated cutaneous vasculitis associated with polyneuropathy presumably due to streptomycine injection.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

A 26 year-old- woman with neuropathy developed erythema, purpura, bullous lesions and subsequent ulcers on the anterior aspects of right leg and left ankle. Pathological examination of punch biopsy specimens taken from ulcerative lesions manifested leukocytoclastic vasculitis. Peroneal nerve and fibular brevis muscle biopsies revealed axonal neuropathy without vasculopathy. The cutaneous vasculitis may be associated with systemic disease or rarely may lead to peripheric polyneuropathy. In cutaneous vasculitis exogenous (i.e.drugs, infectious agents) or endogenous (i.e. malignancies, connective tissue diseases) etiologies have been accused. In the current study we report a very typical patient with isolated cutaneous vasculitis associated with polyneuropathy presumably due to streptomycine injection.

Özet

Yirmialtı yaşında nöropatili bayan hastanın sağ ayak ön yüzünde ve sol ayak bileğinin arka yüzünde eritem, purpura ve büllöz karakterli olup sonradan ülserleşen lezyonlar gelişti. Ülsere lezyonlardan alınan biyopsi materyalinin patolojik inceleme sonucu lökositoklastik vaskülit olarak bildirildi. Peroneal sinir ve fibuler brevis kas biyopsilerinde aksonal nöropati gözlendi fakat vaskülit mevcut değildi. Cilt vaskülitleri sistemik hastalıklarla birlikte olabileceği gibi nadir de olsa periferik polinöropatiye yol açabilir. Cilt vaskülitlerinde ekzojen (ilaç kullanımı, enfeksiyöz ajanlar gibi) ya da endojen (maligniteler, bağ dokusu hastalıkları) etyolojiler araştırılmalıdır. Bu çalışmada streptomisin enjeksiyonuna bağlı olabileceği düşünülen izole cilt vasküliti ve polinöropati birlikteliği rapor edildi.

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Cite This Article

YERLİKAYA, F., ÇAKIR, M. E., KOÇER, A., ÇETİNKAYA, M. (2022). Polinöropati ile birlikte seyreden izole cilt vaskülü. Erciyes Tıp Dergisi, Cilt: 21 - Sayı: 3, 165–170. https://ajindex.com/articles/502978

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