Journals / Erciyes Tıp Dergisi / 2001 / Cilt: 23 - Sayı: 3

Intraarticular neostigmine for postoperative analgesia

Postartroskopik analjezide intraartiküler neostigmin

Pages
111–116
Publication Date
2022-10-17
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Results: The postoperative VAS scores in the three groups were compared with control VAS scores and found as significantly increased (p

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: In this study, we aimed to compare the analgesic effects of intraarticular bupivacaine, bupivacaine + neostigmine mixture or neostigmine alone for postartroscopic analgesia.
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Key Findings & Data:Patients and Methods: ASA I-II, 60 patients, scheduled for arthroscopic surgery, were randomly divided into three groups.
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Conclusion & Impact:Results: The postoperative VAS scores in the three groups were compared with control VAS scores and found as significantly increased (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: In this study, we aimed to compare the analgesic effects of intraarticular bupivacaine, bupivacaine + neostigmine mixture or neostigmine alone for postartroscopic analgesia. Patients and Methods: ASA I-II, 60 patients, scheduled for arthroscopic surgery, were randomly divided into three groups. General anaesthesia was induced with iv 5 mg/kg thiopentone and 0.1 mg/kg pancuronium and maintained by 1-1.5% isofluorane within 50% N2O+O2 mixture in all groups. Postoperatively, intraarticular 75 mg 0.25% bupivacaine was administered to Group I (n=20), 75 mg 0.25% bupivacaine and 500 mg neostigmine mixture to Group II (n=20), and 500 mg neostigmine to Group III (n=20). Postoperative analgesia was evaluated using visual analogue score during the postoperative 30th min and the 1st, 2nd, 4th, 12th, 24th hours. Results: The postoperative VAS scores in the three groups were compared with control VAS scores and found as significantly increased (p

Özet

Amaç: Çalismamizda, intraartiküler bupivakain, bupivakain + neostigmin karışımı ya da tek başina neostigminin, postartroskopik analjezi sağlamada etkinliğini değerlendirmeyi amaçladık. Hastalar ve Yöntem: Tek taraflı artroskopik diz cerrahisi planlanan ASA I-II grubu, 60 olgu rastgele çalismaya alındı. Her üç grupta da olgulara iv 5 mg/kg tiopenton, 0.1mg/kg panküronyum ile anestezi indüksiyonunu takiben %50 N2O+O2 karışımı içinde %1-1.5 izofluran ile genel anestezi uygulandı. Cerrahi işlem tamamlandıktan sonra Grup I'de (n=20) i.a bupivakain %0.25, 75 mg, Grup II'de (n=20) bupivakain %0.25, 75 mg ve 500 mg neostigmin, Grup III'de (n=20) 500 mg neostigmin intraartiküler uygulandı. Postoperatif analjezi visuel analog scale (VAS) ile 30.dk, 1., 2., 4., 12., ve 24. saatlerde değerlendirildi. Bulgular: Her üç grubun postoperatif VAS skorları kontrol VAS skorları ile karşilaştırıldığında istatistiksel olarak anlamlı bir yükselme bulundu (p

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Cite This Article

TERCAN, E., YILDIZ, K., MADENOĞLU, H., DOĞRU, K., BOYACI, A. (2022). Intraarticular neostigmine for postoperative analgesia. Erciyes Tıp Dergisi, Cilt: 23 - Sayı: 3, 111–116. https://ajindex.com/articles/502919

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