Journals / Erciyes Tıp Dergisi / 2003 / Cilt: 25 - Sayı: 1

Induction of anesthesia with sevoflurane in adult patients

Erişkin hastalarda sevofluran ile anestezi indüksiyonu

Pages
21–27
Publication Date
2022-10-17
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Results: While SAP values at intubation were not significantly different from initial values in the sevoflurane group, a significant increase was noted in the thiopental group (p

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Objective & Hypothesis:Purpose: In this study we aimed to compare induction of anesthesia "with sevoflurane, to that with intravenous (IV) thiopental from the point of hemodynamic variations and side effects in adult patients.
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Key Findings & Data:After application of fentanyl 1$mu$g/kg, Group I (n=20, thiopental group) received thiopental (5mg/kg) and group II had (n=20, sevoflurane group) tidal breathing with 50% N2O combined with 6% sevoflurane in O2 for the induction of anesthesia.
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Conclusion & Impact:Results: While SAP values at intubation were not significantly different from initial values in the sevoflurane group, a significant increase was noted in the thiopental group (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: In this study we aimed to compare induction of anesthesia "with sevoflurane, to that with intravenous (IV) thiopental from the point of hemodynamic variations and side effects in adult patients. Material and Metods: Forty ASA class I-III patients undergoing elective abdominal surgical procedures were included in this study. No premedication was administered to the patients. The patients were divided into two groups randomly. After application of fentanyl 1$mu$g/kg, Group I (n=20, thiopental group) received thiopental (5mg/kg) and group II had (n=20, sevoflurane group) tidal breathing with 50% N2O combined with 6% sevoflurane in O2 for the induction of anesthesia. Tracheal intubation was performed after the administration of succinylcholine 1,5 mg/kg. Systolic arterial blood pressure (SAP), diastolic arterial blood pressure (DAP), -and heart rate (HR) values were recorded at preinduction, after induction, after intubation and 5 minutes after intubation. Loss of eyelash reflex time and appearance of the side effects were recorded. Results: While SAP values at intubation were not significantly different from initial values in the sevoflurane group, a significant increase was noted in the thiopental group (p

Özet

Amaç: Bu çalışmada erişkin hastalarda sevofluran indüksiyonu ile İV (intravenöz) indüksiyon ajanı olan tiyopental indüksiyonunu hemodinamik değişiklikler ve yan etkiler açısından karşılaştırmayı amaçladık. Gereç ve Yöntem: Elektif abdominal cerrahi planlanan ASA I-III 40 olgu çalışmaya alındı. Olguların hiçbirine farmakolojik premedikasyon uygulanmadı. Olgular rastgele 2 gruba ayrıldı. Her iki gruptaki olgulara 1$mu$g/kg fentanil İV uygulandıktan sonra Grup I (n=20 tiyopental grubu) 'deki olgulara 5mg/kg tiyopental ile, Grup II (n=20, sevofluran grubu) 'deki olgulara O2 içinde %50 N2O ve %6 sevofluranla tidal soluma tekniği uygulanarak anestezi indüksiyonu yapıldı. Her iki grupta 1,5 mg/kg süksinilkolin İV verilerek entübasyon gerçekleştirildi. 8KB (sistolik kan basıncı), DKB (diyastolik kan basıncı) ve KAH (kalp atım hızı) değerleri; indüksiyona başlamadan önce, indüksiyondan sonra, entübasyondan sonra ve 5. dakikada kaydedildi. Kirpik refleksi kaybolma süresi ve oluşan yan etkiler belirlendi. Bulgular: Sevofluran grubunda 8KB değeri entübasyonda değişmezken, tiyopental grubunda anlamlı olarak yükseldi (p

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Cite This Article

AKIN, A., GÜLER, G., KARAMEHMET, Y., ESMAOĞLU, Ç. A., BOYACI, A. (2022). Induction of anesthesia with sevoflurane in adult patients. Erciyes Tıp Dergisi, Cilt: 25 - Sayı: 1, 21–27. https://ajindex.com/articles/502879

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References (16)

  1. Lerman J, Sikich N, Keinman S, Yentis S. The pharmacology of sevoflurane in infants and children. Anesthesiology 1994; 80:814-818
  2. Ruffle JM, Snider MT. Comparison of rapid and conventional inhalation inductions of halothane oxygen anesthesia in healthy men and women. Anesthesiology 1987; 67:584-587
  3. Editorial: Inhalational induction of anaesthesia-New inspiration? Lancet 1986; 2:84
  4. Goresky GV, Muir J. Inhalation induction of anaesthesia. Can J Anaesth 1996;43:1085- 1089
  5. Kah L, Leng H, Leang T. Single vital capacity inhalational anaesthetic induction in adults- isoflurane vs sevoflurane. Can J Anaesth 1998;45:949-953
  6. Smith I, Nathanson M, White PF. Sevoflurane- a long awaited volatile anaesthetic. Br J Anaesth 1996;76:435-445
  7. Ruffle JM, Snider MT, Rosenberger Jl, Latta WB. Rapid induction of halothane anaesthesia in man. Br J Anaesth 1985;57:607-611
  8. Wilton NTC, Thomas VL. Single breath induction of anaesthesia, using a vital capacity breath of halothane, nitrous oxide and oxygen. Anaesthesia 1986;41:472-476 9. Morgan GE, Mikhail MS. Clinical Anesthesiology (2nd ed). A Simon & Schuster Company, New Jersey 1996, pp 109-127
  9. Hatakeyama N, Ito Y, Momose Y. Effects of sevoflurane, isoflurane, and halothane on mechanical and electrophysiologic properties of canine myocardium. Anest Analg 1993;76:1327-1331
  10. Stern R, Towler S, White P, Evers A. Elimination kinetics of sevoflurane and halothane from blood, brain and adipose tissue in rat. J Anesthesia 1990;71:658-664
  11. Epstein RH, Mendel HG, Guarnieri KM, Staudt SR, Lessin JB, Marr AT. Sevoflurane versus halothane for general anesthesia in pediatric patients. J Clin Anesth 1995;7:237-244
  12. Yasuda N, Lockhart SH, Eger IE, et al. Comparison of kinetics of sevoflurane and isoflurane in humans. Anest Analg 1991;72:316-324
  13. Doi M, Ikeda K. Airway irritation produced by volatile anaesthetic during brief inhalation: comparison of halothane, enflurane, isoflurane and sevoflurane. Can J Anaesth 1993;40:122- 126
  14. Baker CE, Smith I. Sevoflurane. A comparison between vital capacity and tidal breathing techniques for induction of anaesthesia and laringeal mask placement. Anaesthesia 1999;54:841-844
  15. Mendonca C, Thorpe CM. Effect of smoking on induction of anaesthesia with sevoflurane. Anaesthesia 2001;56:19-23
  16. Satoru T, Hideaki T, Kenichi N, Sumihiko S, Akiyoshi N. The effects of sevoflurane, isoflurane, halothane, and enflurane on hemodynamic responses during an inhal