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Journals / Erciyes Tıp Dergisi / 2004 / Cilt: 26 - Sayı: 3

A comparison of electroretinographic values of patients with Bietti's crystalline dystrophy with normal individuals

Bietti'nin kristalin distrofisi saptanan hastaların elektroretinografi değerlerinin normal olgular ile karşılaştırılması

Kuddusi ERKILIÇ
Hakkı DOĞAN
Cem EVEREKLİOĞLU
Ertuğrul MİRZA
Ayşe ÖNER
Abdullah ÖZKIRIŞ
Pages
113–118
Publication Date
2022-10-17
DOI
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The values of these parameters in normal individuals were 114.8±38.7 mV, 231.1±26.4 mV and 88.0±13.9 mV, respectively, and the differences were statistically significant for all responses (for each, P

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To determine the electroretinographic responses in patients with Bietti's crystalline dystrophy and to compare them with normal values.
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Key Findings & Data:Materials-Methods: After a complete ophthalmologic examination, fundus fluorescein angiography (FFA), visual field examination and electrophysiological tests were performed in 11 patients with Bietti's crystalline dystrophy.
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Conclusion & Impact:The values of these parameters in normal individuals were 114.8±38.7 mV, 231.1±26.4 mV and 88.0±13.9 mV, respectively, and the differences were statistically significant for all responses (for each, P
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To determine the electroretinographic responses in patients with Bietti's crystalline dystrophy and to compare them with normal values. Materials-Methods: After a complete ophthalmologic examination, fundus fluorescein angiography (FFA), visual field examination and electrophysiological tests were performed in 11 patients with Bietti's crystalline dystrophy. Visual field examination was performed with Goldmann perimeter and electrophysiological examination with full-field electroretinogram (ERG). ERG values of these patients were compared with normal values of age-and sex matched 15 individuals. Results: There were diffuse or focal pigment epithelial atrophies determined by FFA in all patients with Bietti's crystalline dystrophy. Visual field examination revealed various defects except in two cases. Mean b-wave amplitudes of rod response, maximal combined response and cone response of ERG were 79.1±35.0 mV, 163.0±76.0 mV, and 69.0±27.0 mV, respectively. The values of these parameters in normal individuals were 114.8±38.7 mV, 231.1±26.4 mV and 88.0±13.9 mV, respectively, and the differences were statistically significant for all responses (for each, P

Özet

Amaç: Bietti’nin kristalin distrofisi olan olgularda elektroretinografik yanıtların saptanması ve normal değerler ile karşılaştırılması. Yöntem-Gereç: Bietti'nin kristalin distrofisi saptanan 11 hastaya tam oftalmolojik muayene sonrası fundus floresein anjiografi (FFA), görme alanı ve elektrofizyolojik testler uygulandı. Görme alanı muayenesi Goldmann perimetresi, elektroretinografik değerlendirme ise tüm alan elektroretinogram (ERG) ile yapıldı. Bu olgularda saptanan ERG değerleri, yaş ve cinsiyet bakımından uyumlu 15 normal bireyin ERG değerleri ile karşılaştırıldı. Bulgular: Bietti'nin kristalin distrofili olguların tümünde, FFA’da yaygın veya kısmi retina pigment epitel atrofileri mevcut idi. Görme alanı muayenesinde 2 olgu dışında çeşitli görme alanı defektleri saptandı. ERG’de ortalama rod yanıtı, maksimal kombine yanıt ve kon yanıtı b-dalga amplitüdleri sırası ile 79.1±35.0 mV, 163.0±76.0 mV ve 69.0±27.0 mV idi. Normal olgularda ise bu değerler sırası ile 114.8±38.7 mV, 231.1±26.4 mV ve 88.0±13.9 mV idi ve aradaki fark tüm yanıtlar bakımından istatistiksel olarak anlamlı idi (her biri için, P

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Cite This Article

ERKILIÇ, K., DOĞAN, H., EVEREKLİOĞLU, C., MİRZA, E., ÖNER, A., ÖZKIRIŞ, A. (2022). A comparison of electroretinographic values of patients with Bietti's crystalline dystrophy with normal individuals. Erciyes Tıp Dergisi, Cilt: 26 - Sayı: 3, 113–118. https://ajindex.com/articles/502842

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References (17)

  1. Gündüz K, Günalp İ, Atik Ü, Ergin A. Bietti'nin kristalin distrofisi. MN Oftalmoloji 1994;1:97- 99
  2. Eldem B, İrkeç M. İki olgu nedeni ile Bietti'nin kristalin retina ve kornea distrofısi. T Oft Gaz 1989;19:602-607
  3. Bozkır DM, Ekinciler ÖF, Mirza E, Doğan H. Bietti'nin kristalin distrofisi. XXV. Ulusal Türk Oftalmoloji Kongresi Bülteni. İstanbul 1991;178-183
  4. Kaiser-Kupfer MI, Chan CC, Markello TC, Crawford MA, Caruso RC, Csaky KG, Guo J, Gahl WA. Clinical biochemical and pathologic correlations in Bietti's crystalline dystrophy. Am J Ophthalmol 1994;118:569-582
  5. Jurklies B, Jurklies C, Schmidt U, Wessing A. Bietti's crystalline dystrophy of the retina and cornea. Retina 1999;19:168-71
  6. Lee J, Jiao X, Hejtmancik JF, Kaiser-Kupfer M, Gahl WA, Markello TC, Guo J, Chader GJ. The metabolism of fatty acids in human Bietti crystalline dystrophy. Invest Ophthalmol Vis Sci 2000;42:1707-14
  7. Lee J, Jiao X, Hejtmancik JF, Kaiser-Kupfer M, Chader GJ. Identification, isolation, and characterization of a 32-kDa fatty acid-binding protein missing from lymphocytes in humans with Bietti crystalline dystrophy (BCD). Mol Genet Metab 1998;65:143-54
  8. Wilson DJ, Weleber DJ, Klein ML, Welch RB, Green WR. Bietti's crystalline dystrophy: a clinicopathologic correlative study. Arch Ophthalmol 1989;107:213-221
  9. Hayasaka S, Okuyama S. Crystalline retinopathy. Retina 1984;4:177-81
  10. Yoshida A, Nara Y, Takahashi M. Crystalline retinopathy: evaluation of blood-retinal barrier by vitreous fluorophotometry. Jpn J Ophthalmol 1985;29:290-300
  11. Weber U, Adler K, Hennekes R. Crystalline chorioretinopathy with marginal corneal involvement. Klin Monatsbl Augenheilkd 1984;185:268-71
  12. Eldem B, Kiratli H, Tuncel M. Electron microscopic findings in Bietti's crystalline dystrophy. Ann Ophthalmol 1995;27:9–14
  13. Chan WM, Pang CP, Leung AT, Fan DS, Cheng AC, Lam DS. Bietti crystalline retinopathy affecting all 3 male siblings in a family. Arch Ophthalmol 2000;118:129-31
  14. Güven D, Aksünger A, Akbatur H, Or M. Bir olgu nedeniyle Bietti'nin kristalin retina distrofisi. Retina 1994;2:206-208
  15. Sanderson PO, Kuwabara T, Stark WJ, Wong VG, Collins EM. Cystinosis. A clinical, histopathologic, and ultrastructural study. Arch Ophthalmol 1974;91:270-4
  16. Mauldin WM, O'Connor PS. Crystalline retinopathy: Bietti's tapetoretinal degeneration without marginal corneal dystrophy. Am J Ophthalmol 1981;92:640-46
  17. Kretschmann U, Usui T, Ruether K. Electroretinographic c