Journals / Erciyes Tıp Dergisi / 2004 / Cilt: 26 - Sayı: 1

Acepromazine-propofol anesthesia in rabbits

Tavşanlarda acepromazine-propofol anestezisi

Pages
1–6
Publication Date
2022-10-17
DOI
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⚡ TL;DR(Too Long; Didn't Read)

However, a decrease in respiration rate (p

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Objective & Hypothesis:Aim: In this study, we aimed to evaluate the acepromazine-propofol anesthesia in rabbits.Material and Methods: Five New Zealand white rabbits, 3 months of age and 1.400-2.000 g in weight are included in the study.
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Key Findings & Data:Acepromazine (10 mg/kg, im) was administered for premedication anesthesia and propofol (10 mg/kg, iv) was maintained fifteen minutes following administration via v. auricularis lateralis.
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Conclusion & Impact:However, a decrease in respiration rate (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: In this study, we aimed to evaluate the acepromazine-propofol anesthesia in rabbits.Material and Methods: Five New Zealand white rabbits, 3 months of age and 1.400-2.000 g in weight are included in the study. Acepromazine (10 mg/kg, im) was administered for premedication anesthesia and propofol (10 mg/kg, iv) was maintained fifteen minutes following administration via v. auricularis lateralis. Intermittent arterial blood samples were taken from left femoral arteria at predetermined intervals (0,20,30,40 minutes)before and after anesthesia, and the pH, $pCO_2$, $p0_2$ and $O_2$ saturations levels measured. Data concerning reflexes, pain and physiological parameters (heart rate, respiration rate, body temperature) were recorded at the pre-determined intervals. The duration of anesthesia, maintaining sternal recumbency and standing position were also recorded. Results: Mean anesthesia time, sternal recumbency time and standing time were recorded as 14.40 min±1.12 min, 33.20 min+2.47 minand 47.00 min±5.15 min, respectively. No statistically significant differences were determined for $pC0_2$ and $pO_2$ (p>0.05). However, a decrease in respiration rate (p

Özet

Amaç: Bu çalışmada tavşanlarda acepromazine (Vetranquil)-propofol (Diprivan) anestezisinin değerlendirilmesi amaçlandı. Materyal ve Metod: Ağırlıkları 1400-2000 gr arasında değişen, 3 aylık, 5 Yeni Zelanda tavşanı kullanıldı. Hayvanlarda, acepromazine (10mg/kg,im) 15 dakika sonra da propofol (10mg/kg,iv) vena auricularis lateralis'ten uygulandı. Anestezi öncesi ve anestezi sonrasında (0,20,30,40 dakikalarda) sol a. femoralis'ten kan alınarak pH,$pCO_2$,$pO_2$,$O_2$ saturasyonu, ayrıca bu periyotlarda kalp atım sayısı, solunum sayısı, vücut ısısı, ağrı bulguları, refleksler ve anestezi, göğüs üzerine yatabilme ve tamamen ayakta durabilme süreleri yönünden değerlendirildi. Bulgular: Ortalama anestezi süresi 14.40 dk ± 1.12 dk; göğüs üzerine yatabilme süresi 33.20 dk ± 2.47 dk ve ayakta durabilme süresi 47.00 dk + 5.15 dk olarak belirlendi. Belirtilen periyodlarda alınan arteriyel kan örneklerinde $pCO_2$ ve $pO_2$ değerlerinde farklılık (p>0.05) önemsiz olarak gözlenmiştir. Solunum oranındaki düşüş (p

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Cite This Article

KOÇ, B., KAYA, A., KAYA, Ü., APAYDIN, N. (2022). Acepromazine-propofol anesthesia in rabbits. Erciyes Tıp Dergisi, Cilt: 26 - Sayı: 1, 1–6. https://ajindex.com/articles/502830

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