Journals / Erciyes Tıp Dergisi / 2005 / Cilt: 27 - Sayı: 2

Evaluation of the effects of serum bilirubin levels on intimal medial hyperplasia of carotis vessels

Serum bilirubin düzeyinin karotisin intimal-medial hiperplazisi üzerine etkisinin incelenmesi

Pages
53–57
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Diabetes (OR: 1.38, CI 95 %) and smoking ( OR: 0.90, CI 95 %) were not found as risk factors for intimal medial hyperplasia.Conclusion: Low serum total bilirubin level could be suggested as a risk factor for carotid intimal medial hyperplasia.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To investigate whether there is an independent effect of serum total bilirubin level on carotid atherosclerosis.Material and Metods: A total number of 145 subjects was used in this case-control type study.
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Key Findings & Data:While 75 of the subjects had intimal medial hyperplasia in their carotid arteries, 70 of subjects served as the control group who had the same risk factors without intimal medial hyperplasia.
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Conclusion & Impact:Diabetes (OR: 1.38, CI 95 %) and smoking ( OR: 0.90, CI 95 %) were not found as risk factors for intimal medial hyperplasia.Conclusion: Low serum total bilirubin level could be suggested as a risk factor for carotid intimal medial hyperplasia.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To investigate whether there is an independent effect of serum total bilirubin level on carotid atherosclerosis.Material and Metods: A total number of 145 subjects was used in this case-control type study. While 75 of the subjects had intimal medial hyperplasia in their carotid arteries, 70 of subjects served as the control group who had the same risk factors without intimal medial hyperplasia. Intimal medial hyperplasia was used as a dependent variable whereas hypertension, diabetes, high cholesterol levels, smoking and serum bilirubin levels were used as independent variables.Results: There were no differences between groups when age and sex were compared. Low total bilirubin level was found to be a risk factor for intimal medial hyperplasia as a result of logistic regression analysis [OR: 1.57, confidential limit 95% (1.16-1.93)]. On the other hand, hypertension (OR: 0.28, CI 95 %) and, hypercholesterolemia (OR: 0.31, CI 95 %) were found to be risk factors for intimal medial hyperplasia. Diabetes (OR: 1.38, CI 95 %) and smoking ( OR: 0.90, CI 95 %) were not found as risk factors for intimal medial hyperplasia.Conclusion: Low serum total bilirubin level could be suggested as a risk factor for carotid intimal medial hyperplasia.

Özet

Amaç: Serum total bilirubin düzeyinin karotis aterosklerozu üzerine bağımsız bir etkisinin olup olmadığını incelemek.Gereç ve Yöntem: Toplam 145 kişi vaka-kontrol tipindeki bu çalışmaya dahil edildi. İntimal medial hiperplazi tespit edilen 75 kişi vaka grubuna, ateroskleroz için aynı risk faktörlerine sahip olan ancak intimal medial hiperplazi tespit edilmeyen 70 kişi ise kontrol grubuna alındı. Bağımlı değişken olarak intimal medial hiperplazi, bağımsız değişken olarak ise hipertansiyon, diabet, kolesterol yüksekliği, aktif sigara kullanımı ve serum total bilirubini kullanıldı.Bulgular: Gruplar arasında yaş ve cinsiyet farkı yoktu. Mutiple lojistik regresyon analizi sonucunda düşük serum total bilirubin düzeyinin intimal medial hiperplazi için risk faktörü olduğu saptandı (OR 1.57, %95 güvenlik sınırı 1.16-1.93). Hipertansiyonun (OR 0.28, %95 güvenlik sınırı 0.16-0.36) ve hiperkolesteroleminin (OR 0.31, %95 güvenlik sınırı 0.23-0.42) intimal medial hiperplazi için risk faktörü olduğu gözlendi. Diabetes mellitusun (OR 1.38, %95 güvenlik sınırı 0.97-1.84) ve aktif sigara kullanımının ise (OR 0.90, %95 güvenlik sınırı 0.68-1.16) intimal medial hiperplazi için risk faktörü olmadığı saptandı. Sonuç: Düşük serum total bilirubin düzeyi karotis intimal medial hiperplazi için risk faktörü olabileceği gözlendi.

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Cite This Article

BOLAYIR, E., DEMİREL, Y., TOPAKTAŞ, S., TAŞ, A., TAŞ, F. (2022). Evaluation of the effects of serum bilirubin levels on intimal medial hyperplasia of carotis vessels. Erciyes Tıp Dergisi, Cilt: 27 - Sayı: 2, 53–57. https://ajindex.com/articles/502823

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