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Journals / Erciyes Tıp Dergisi / 2005 / Cilt: 27 - Sayı: 1

DNA positivity of hepatitis B virus and serological tests

Hepatit B virus DNA pozitifliği ve serolojik testler

Fadile Yıldız ZEYREK
Uzala Ayser MIZRAKLI
Bülent TÜMKAYA
Hatice ÖZBİLGE
Pages
17–21
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: It was concluded that in order to evaluate serologic markers of patients, HB V DNA positivity, other liver laboratory tests, treatment and clinical appearance should all be considered.

📌 3 Key Takeaways

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Objective & Hypothesis:with pre-diagnosis of hepatitis B virus infection were examined; serological markers and therapy situation of patients with HB V DNA positive were compared.
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Key Findings & Data:Results: HBV DNA was positive in 86 (41 %) of the sera of 208 patients.
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Conclusion & Impact:Conclusion: It was concluded that in order to evaluate serologic markers of patients, HB V DNA positivity, other liver laboratory tests, treatment and clinical appearance should all be considered.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

with pre-diagnosis of hepatitis B virus infection were examined; serological markers and therapy situation of patients with HB V DNA positive were compared. Material and Methods: HBV DNA was investigated by quantitation of DNA using real-time polymerase chain reaction (PCR) and serological markers by enzyme immunoassay (EIA). Results: HBV DNA was positive in 86 (41 %) of the sera of 208 patients. The HBV DNA was detected in 74 (51 %)of 145 HBsAg positive patients, in 29 (80.5 %) of 36 HBeAg positive patients and in 49 (39.2%) of 125 antiHBe positive patients. Conclusion: It was concluded that in order to evaluate serologic markers of patients, HB V DNA positivity, other liver laboratory tests, treatment and clinical appearance should all be considered.

Özet

Amaç:Hepatit B ön tanısı ile laboratuvara gönderilen örnekler üzerinde yapılan bu çalışmada, Hepatit B Virus (HBV) DNA pozitifliği tespit edilen hastaların serolojik testlerinin durumu ve hastanın o sırada tedavi alıp almadığı incelenmiştir. Gereç tie Yöntem: HBV DNA kantitatif olarak real time polimeraz zincir reaksiyon (PCR)' uyla, serolojik testler ise enzim immuno assay (E/A) yöntemiyle çalışılmıştır. Bulgular: HBV DNA ve HBV seroloji çalışılan toplam 208 serumun 86 (% 41)' sında HBV DNA pozitifliği bulunmuştur.. HBsAg pozitif 145 örneğin 74 (% 51)'ünde, HBeAg pozitif 36 örneğin 29 (% 80.5)'unda, antiHBe pozitif 125 örneğin 49 (% 39.2)'unda HBV DNA varlığı saptanmıştır. Sonuç: Sonuç olarak hastayı değerlendirirken serolojik değerler, HBV DNA pozitifliği, diğer laboratuvar testleri, hastanın tedavi alıp almadığı ve hastanın kliniği bir bütün olarak düşünülmelidir.

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Cite This Article

ZEYREK, F. Y., MIZRAKLI, U. A., TÜMKAYA, B., ÖZBİLGE, H. (2022). DNA positivity of hepatitis B virus and serological tests. Erciyes Tıp Dergisi, Cilt: 27 - Sayı: 1, 17–21. https://ajindex.com/articles/502821

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