Journals / Erciyes Tıp Dergisi / 2005 / Cilt: 27 - Sayı: 4

Histomorphologic evaluation of the development of the esophagus between 17 and 32 weeks old human fetuses

Özofagus’un gelişiminin 17 ile 32 haftalar arasındaki fetuslerde histomorfolojik olarak değerlendirilmesi

Pages
152–157
Publication Date
2022-10-17
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Fetal development of the esophagus accelerates after approximately 21 weeks and ending coarsely after 27 weeks.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Purpose: The embryonic development of the esophagus progresses very complexly and systematically.
📊
Key Findings & Data:The aim of this study was to the histological evaluation of the esophagus in 17-32 week old human fetuses.
💡
Conclusion & Impact:Conclusion: Fetal development of the esophagus accelerates after approximately 21 weeks and ending coarsely after 27 weeks.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: The embryonic development of the esophagus progresses very complexly and systematically. The aim of this study was to the histological evaluation of the esophagus in 17-32 week old human fetuses. Material and Methods: 20 human fetuses whose ages ranged between 17-32 week-old and all of which were collected by University of Selcuk Meram Faculty of Medicine Department of Anatomy via spontaneous abortus under ethic rules were included in this study. The tissue samples of the esophagus were excised and processed with routine histologic methods, embedded in paraffin, stained with Hematoxylin-Eosin and evaluated light microscopically. Results: The histologic organization of the esophagus of the 17-20 week old fetuses was poor. However, the organization was accelerated after 21 weeks and almost finished after approximately 27 weeks. Conclusion: Fetal development of the esophagus accelerates after approximately 21 weeks and ending coarsely after 27 weeks.

Özet

Amaç: Gastrointestinal sistemin embriyonik dönemde gelişimi oldukça kompleks ve sistematik bir tarzda ilerler. Bu çalışmanın amacı insan özofagus’unun fetal dönemde 17-32 haftalar arasında gelişiminin histolojik olarak incelenmesidir. Gereç ve Yöntem: Bu çalışmada Selçuk Üniversitesi Meram Tıp Fakültesi Anatomi Anabilim Dalında bulunan ve spontan düşük sonucu elde edilmiş ve etik olarak piyes haline getirilmiş insan fetüslerinden gebelik haftası 17 ila 32 arasında değişen 20 tanesi seçildi. Bu fetüslerden alınan özofagusa ait doku parçaları rutin histolojik doku takibi metodları ile takip edilip parafine gömüldü ve Hematoksilen-Eosin ile boyanıp ışık mikroskobunda incelendi. Bulgular: 17-20 haftalar arasında özofagus histolojik yapısının henüz oldukça zayıf organizasyon gösterdiği, 21. haftada organizasyonun daha hızlandığı ve 27. haftada özofagus’un normal histolojik bileşenlerinin büyük kısmının genel anlamda yerleştiğini belirledik. Sonuç: Özofagus’un fetal dönemde gelişimi 21. hafta civarında hızlanmakta ve 27. hafta civarında genel anlamda tüm histolojik yapılar organize olmaktadır

🔖

Cite This Article

TUNCER, I., KALKAN, S., SOYLU, R., TOSUN, M. (2022). Histomorphologic evaluation of the development of the esophagus between 17 and 32 weeks old human fetuses. Erciyes Tıp Dergisi, Cilt: 27 - Sayı: 4, 152–157. https://ajindex.com/articles/502812

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Williams PL, Bannister LH, Berry MM, et al. Embryology and Development. In: Collins P. (ed), Gray’s Anatomy. Churcill Livingstone Inc, New York, 1995; pp181-185
  2. Moore KL and Persaud TVN The Digestive System. In: Moore KL (ed), The Developing Human (Clinically Oriented Embryology), Sixth Edition, WB Saunders Company, 1998; 271-302
  3. Larsen WJ. Development of the Gastrointestinal Tract In Human Embryology, Churcill Livingstone Inc, 1993; 235-280
  4. Şeftalioğlu A. Sindirim Sistemi Geliþmesi. In: Şeftalioğlu A (ed), Genel & Özel İnsan Embriyolojisi. Üçüncü Baskı. Feryal Matbaası; Ankara 1998;ss 291-327
  5. Herbst JJ. The oesophagus. In: Behrman RE et al (eds), Nelson Textbook of Pediatrics,Philadelphia, WB Saunders, 1996. pp803-808 6. Patapoutian A, Wold BJ, Wagner RA. Evidence for developmentally programmed transdifferentiation in mouse esophageal muscle. Science 1995; 15; 270 (5243):1818- 1821
  6. Gemonov VV, Kolesnikov LL Development of oesophageal tissue structures in human embryogenesis. Anat Anz. 1990; 171(1):13-15
  7. Worl J, Dutsch F, Neuhuber WL. Development of neuromuscular junctions in the mouse esophagus: focus on establishment and reduction of enteric co-innervation. Anat Embryol (Berl) 2002;205:141-152
  8. Polin RA, Fox WW. Standards and Measurements. In: Hensinger R.N (ed), Fetal and Neonatal Physiology, WB Saunders Company, Philadelphia.1992;pp1688-1696
  9. Suri S, Eradi B, Chowdhary SK, Narasimhan KL, Rao KL. Early postoperative feeding and outcome in neonates. Nutrition. 2002;18:380-382
  10. Dashe JS, McIntire DD, Ramus RM, Santos-Ramos R, Twickler DM. Hydramnios: anomaly prevalence and sonographic detection.Obstet Gynecol. 2002;100:134-139
  11. Kimble RM, Breier BH, Gluckman PD, Harding JE. Enteral IGF-I enhances fetal growth and gastrointestinal development in oesophageal ligated fetal sheep. J Endocrinol 1999;162:227-235
  12. Karnak I, Tanyel FC, Muftüoğlu S, et al. Esophageal ligation: effects on the development of fetal organic systems Eur J Pediatr Surg 1996;6:328-333
  13. Jacobs DG, Wesson DE, Mago-Cao H, et al. Effect of esophageal ligation on the growth of fetal rabbits.J Pediatr Gastroenterol Nutr 1989;8:245-251
  14. DeNardi FG, Riddell RH. The normal esophagus. Am J Surg Pathol 1991;15:296-309.