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Journals / Erciyes Tıp Dergisi / 2005 / Cilt: 27 - Sayı: 4

Thrombotic thrombocytopenic purpura associated with malignancy: Report of two cases

Maligniteye bağlı trombotik trombositopenik purpura: 2 olgu sunumu

Mustafa ÇETİN
Aydın ÜNAL
Bülent ESER
Tansu SAV
Çoban Özlem YÜKSEL
Metin ÖZKAN
İsmail SARI
Pages
180–183
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Thus, this group of patients should be treated with chemotherapy combined with supportive treatment such as plazma exchange.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Microangiopathic hemolytic anemia (MAHA) is a late but fatal complication in advanced cancers.
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Key Findings & Data:In this paper, we report two cases presenting with a thrombotic thrombocytopenic purpura (TTP) with malignancy refractory to daily plasma exchange.
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Conclusion & Impact:Thus, this group of patients should be treated with chemotherapy combined with supportive treatment such as plazma exchange.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Microangiopathic hemolytic anemia (MAHA) is a late but fatal complication in advanced cancers. In this paper, we report two cases presenting with a thrombotic thrombocytopenic purpura (TTP) with malignancy refractory to daily plasma exchange. The prognosis of the patients with TTP associated with malignancy are not as favorable as in the patients with classical TTP. Thus, this group of patients should be treated with chemotherapy combined with supportive treatment such as plazma exchange.

Özet

Mikroanjiopatik hemolitik anemi (MAHA) ileri evre kanserlerin geç fakat ölümcül bir komplikasyonudur. Bu yazıda, maligniteye bağlı trombotik trombositopenik purpura (TTP) gelişen ve günlük plazma değişimi tedavisine dirençli olan iki olgu sunulmuştur. Maligniteye bağlı TTP gelişen hastaların prognozları, klasik TTP’den farklı olarak daha kötüdür. Bu nedenle, bu grup hastalar kemoterapi ile tedavi edilmeli ve plazma değişimi gibi yöntemler destekleyici tedavi olarak kullanılmalıdır.

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Cite This Article

ÇETİN, M., ÜNAL, A., ESER, B., SAV, T., YÜKSEL, Ç. Ö., ÖZKAN, M., SARI, İ. (2022). Thrombotic thrombocytopenic purpura associated with malignancy: Report of two cases. Erciyes Tıp Dergisi, Cilt: 27 - Sayı: 4, 180–183. https://ajindex.com/articles/502801

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