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Journals / Erciyes Tıp Dergisi / 2007 / Cilt: 29 - Sayı: 4

Investigation of metabolic parameters in patients with idiopathic hyperandrogenemia

İdiopatik hiperandrojenemili hastalarda metabolik parametrelerin değerlendirilmesi

Züleyha KARACA
Fatih TANRIVERDİ
Kürşat ÜNLÜHIZARCI
Mehmet Emin ÇAPAK
Fahrettin KELEŞTİMUR
Pages
274–279
Publication Date
2022-10-17
DOI
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Serum lipid profiles were also analyzed in both the patients and control group.Results:Although there was no difference between fasting glucose levels in the patients and control subjects, basal insulin levels were significantly higher in the patient group (p

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose:The diseases characterized with hyperandrogenemia may be associated with carbonhydrate and lipid disorders.
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Key Findings & Data:In the present study, insulin resistance, glucose intolerance and dyslipidemia were assessed in patients with idiopathic hyperandrogenemia.Material and Methods:Ten female patients with idopathic hyperandrogenemia and, 10 age and body mass index matched healthy women were involved in the study.
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Conclusion & Impact:Serum lipid profiles were also analyzed in both the patients and control group.Results:Although there was no difference between fasting glucose levels in the patients and control subjects, basal insulin levels were significantly higher in the patient group (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose:The diseases characterized with hyperandrogenemia may be associated with carbonhydrate and lipid disorders. In the present study, insulin resistance, glucose intolerance and dyslipidemia were assessed in patients with idiopathic hyperandrogenemia.Material and Methods:Ten female patients with idopathic hyperandrogenemia and, 10 age and body mass index matched healthy women were involved in the study. All patients had hirsutism, hyperandrogenemia and regular ovulatory menstrual cycles.Patients with thyroid dysfunction, diabetes mellitus, adrenal or ovarian tumors were excluded from the study. Adrenocorticotropin (ACTH) stimulation test was performed to exclude non-classical adrenal hyperplasia in patients. Glucose and insulin responses to OGTT were assessed. Serum lipid profiles were also analyzed in both the patients and control group.Results:Although there was no difference between fasting glucose levels in the patients and control subjects, basal insulin levels were significantly higher in the patient group (p

Özet

Amaç:Androjen artışıyla karakterize hastalıklar karbonhidrat ve lipid metabolizması bozukluklarıyla ilişkili olabilirler. Bu çalışmada, idiopatik hiperandrojenemi olarak tanımlanan hasta grubu insülin direnci, glukoz intoleransı ve dislipidemi açısından değerlendirildi. Gereç ve Yöntemler:Çalışma idiopatik hiperandrojenemi tanısı alan 10 kadın hasta ve benzer yaş ve vücut kitle indeksine sahip 10 sağlıklı kadından oluşturuldu. Hastaların tümünde hirsutizm, hiperandojenemi, düzenli mentruel sikluslar mevcuttu.Tiroid disfonksiyonu, hiperprolaktinemi, diabetes mellitus, adrenal veya over tümörü olan hastalar çalışmaya dahil edilmedi. Hastalara non-klasik adrenal hiperplaziyi dışlamak için, adrenokortikotropin (ACTH) stimülasyon testi yapıldı. Hasta ve kontrol grubunun oral glukoz tolerans testi (OGTT)’ne glukoz ve insülin cevaplarına bakıldı. Ayrıca her iki grubun lipid profilleri değerlendirildi. Bulgular:Hasta ve konrol grubunun ortalama açlık glukoz değerleri arasında fark olmamasına rağmen, bazal insülin değerleri hasta grubunda anlamlı şekilde yüksekti (p

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Cite This Article

KARACA, Z., TANRIVERDİ, F., ÜNLÜHIZARCI, K., ÇAPAK, M. E., KELEŞTİMUR, F. (2022). Investigation of metabolic parameters in patients with idiopathic hyperandrogenemia. Erciyes Tıp Dergisi, Cilt: 29 - Sayı: 4, 274–279. https://ajindex.com/articles/502744

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