Journals / Erciyes Tıp Dergisi / 2009 / Cilt: 31 - Sayı: 3

A pitfall in cytological examination of salivary gland neoplasm - pleomorphic adenoma with extensive squamous metaplasia

Tükrük bezi tümörlerinin sitolojik incelemesinde tuzak - yaygın skuamöz metaplazi gösteren pleomorfik adenom

Pages
272–275
Publication Date
2022-10-17
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We present a case of pleomorphic adenoma with extensive squamous metaplasia in a total parotidectomy specimen which was misdiagnosed as epidermal cyst in preoperative FNAC.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Pleomorphic adenoma (benign mixt tumor) is most common in adults during third through fifth decades of life.
📊
Key Findings & Data:Approximately 70% of pleomorphic adenomas occur in the parotid gland.
💡
Conclusion & Impact:We present a case of pleomorphic adenoma with extensive squamous metaplasia in a total parotidectomy specimen which was misdiagnosed as epidermal cyst in preoperative FNAC.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Pleomorphic adenoma (benign mixt tumor) is most common in adults during third through fifth decades of life. Approximately 70% of pleomorphic adenomas occur in the parotid gland. Pleomorphic adenoma occasionally reveals focal squamous metaplastic changes. However extensive squamous metaplasia is rare. These cases can be misdiagnosed in preoperative fine-needle aspiration cytology (FNAC) and intraoperative frozen section studies. We present a case of pleomorphic adenoma with extensive squamous metaplasia in a total parotidectomy specimen which was misdiagnosed as epidermal cyst in preoperative FNAC.

Özet

Pleomorfik adenom (benign mikst tümör) sıklıkla 3-5 inci dekatta görülmektedir. Parotis bezindeki tüm tümörlerin yaklaşık %70’i pleomorfik adenomdur. Pleomorfik adenomlar nadiren fokal skuamöz metaplastik değişiklikler gösterebilir. Ancak yaygın skuamöz metaplazi nadirdir. Bu olgular operasyon öncesinde ince iğne aspirasyon biyopsisi ve operasyon sırasında dondurulmuş kesit çalışmalarında farklı tanılar alabilir. Bu yazıda operasyon öncesi parotisteki kitleden yapılan ince iğne aspirasyon sitolojisinde epidermal kist tanısı alan ve total parotidektomi spesmeninde yaygın skuamöz metaplazi gösteren pleomorfik adenom olarak rapor edilen 35 yaşındaki kadın olgu sunuldu.

🔖

Cite This Article

GÜNEY, E., YÜCE, İ., ÇAĞLI, S., ÖZTÜRK, M., TAŞDEMİR, A., SOYUER, I. (2022). A pitfall in cytological examination of salivary gland neoplasm - pleomorphic adenoma with extensive squamous metaplasia. Erciyes Tıp Dergisi, Cilt: 31 - Sayı: 3, 272–275. https://ajindex.com/articles/502627

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (8)

  1. Seifert G, Langrock I, Donath K. A pathological classification of pleomorphic adenoma of the salivary glands (author's transl). HNO 1976; 24:415-426
  2. Ahn MS, Hayashi GM, Hilsinger RL, Lalwani AK. Familial mixed tumors of the parotid gland. Head Neck 1999; 21:772-775
  3. Hamdan K, Maly B, Elashar R, Gross M. Mucinous and squamous metaplasia in benign tumors of the parotid gland: a potential pitfall in the diagnosis. Otolaryngol Head Neck Surg 2005;133:987-988
  4. Draeger A, Nathrath WB, Lane EB, Sundström BE, Stigbrand TI Cytokeratins, smooth muscle actin and vimentin in human normal salivary gland and pleomorphic adenomas. Immunohistochemical studies with particular reference to myoepithelial and basal cells. APMIS 1991; 99:405-415
  5. Dardick I, van Nostrand AW, Jeans MT, Rippstein P, Edwards V. Pleomorphic adenoma, I: Ultrastructural organization of "epithelial" regions. Hum Pathol 1983;14:780-797
  6. Jayaram G, Pathmanathan R, Khanijow V Cystic lesion of the parotid gland with squamous metaplasia mistaken for squamous cell carcinoma. A case report. Acta Cytol 1998; 42:1468-1472
  7. Savera AT, Gown AM, Zarbo RJ Immunolocalization of three novel smooth muscle-specific proteins in salivary gland pleomorphic adenoma: assessment of the morphogenetic role of myoepithelium. Mod Pathol 1997; 10:1093-1100
  8. Su CC, Chou CW, Yiu CY. Neck mass with marked squamous metaplasia: a diagnostic pitfall in aspiration cytology. J Oral Pathol Med 2008; 37:56-58.