Journals / Erciyes Tıp Dergisi / 2009 / Cilt: 31 - Sayı: 1

Midenin hepatoid adenokarsinomu: Olgu sunumu

Hepatoid adenocarcinoma of the stomach: A case report

Pages
79–82
Publication Date
2022-10-17
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The diagnosis of hepatoid adenocarcinoma of stomach is not dependent on whether alpha fetoprotein is produced; actually, histological features are important for diagnosis

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Hepatoid adenocarcinoma is a rare variant of adenocarcinoma of the stomach with a very poor prognosis.
📊
Key Findings & Data:Hepatoid adenocarcinoma is characterized by a distinct morphology and immunohistochemistry, clinically characterized by the increased level of serum alpha fetoprotein.
💡
Conclusion & Impact:The diagnosis of hepatoid adenocarcinoma of stomach is not dependent on whether alpha fetoprotein is produced; actually, histological features are important for diagnosis
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Hepatoid adenocarcinoma is a rare variant of adenocarcinoma of the stomach with a very poor prognosis. Hepatoid adenocarcinoma is characterized by a distinct morphology and immunohistochemistry, clinically characterized by the increased level of serum alpha fetoprotein. Microscopic findings include both adenocarcinomatous and hepatoid elements. The diagnosis of hepatoid adenocarcinoma of stomach is not dependent on whether alpha fetoprotein is produced; actually, histological features are important for diagnosis

Özet

Hepatoid adenokarsinom, midenin kötü prognozlu nadir bir adenokarsinom formudur. Hepatoid adenokarsinom farklı morfoloji ve immunohistokimya, klinik olarak artmış serum alfa fetoprotein düzeyleri ile karakterizedir. Mikroskobik bulgular hem adenokarsinom hem de hepatoid elementleri içerir. Midenin hepatoid adenokarsinom tanısı alfa fetoprotein üretip üretmediğine bağlı değildir; gerçekte, tanı için histolojik özellikler önemlidir.

🔖

Cite This Article

BİLİCİ, M., TEKİN, S. B., ÇAYIR, K., YILMAZ, Ö., GÜRSAN, N. (2022). Midenin hepatoid adenokarsinomu: Olgu sunumu. Erciyes Tıp Dergisi, Cilt: 31 - Sayı: 1, 79–82. https://ajindex.com/articles/502584

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. Lowitz BB, Casciato DA. Principles of Oncology. In: Casciato DA, editor. Manual of Clinical Oncology. Philadelphia: Lippincott Williams & Wilkins; 2004. p.12
  2. Fujii H, Ichikawa K, Takagaki T, et al. Genetic evolution of alpha fetoprotein producing gastric cancer. J Clin Pathol 2003; 56: 942-949
  3. Inagawa S, Shimazaki J, Hori M, et al. Hepatoid adenocarcinoma of the stomach. Gastric Cancer 2001; 4: 43-52
  4. Ishikura H, Fukasawa Y, Ogasawara K, Natori T, Tsukada Y, Aizawa M. An AFP- producing gastric carcinoma with features of hepatic differentiation: a case report. Cancer 1985; 56: 840-848
  5. Ishikura H, Kirimoto K, Shamoto M, et al. Hepatoid adenocarcinomas of stomach: an analysis of seven cases. Cancer 1986; 58: 119-126
  6. Górnicka B, Ziarkiewicz-Wróblewska B, Muszyñski J, et al. Carcinoma hepatoides of the stomach-case report and literature review. Wiad Lek 2003; 56: 481-485
  7. Akiyama S, Tamura G, Endoh Y, et al. Histogenesis of hepatoid adenocarcinoma of the stomach: Molecular evidence of identical origin with coexistent tubular adenocarcinoma. Int J Cancer 2003; 106: 510-515
  8. Kaiser U, Zugmaier G, Frank M, Riedel I, Neubauer A, Moll R. AFP-producing adenocarcinoma of the stomach. A rare tumor with poor prognosis. (article in German) Pathologe 2003; 24: 141-145
  9. Kanda T, Yoshida H, Mamada Y, et al. Resection of liver metastases from an alpha-fetoprotein-producing gastric cancer. J Nippon Med Sch 2005; 72: 66-70
  10. Shimada S, Hayashi N, Marutsuka T, et al. Irinotecan plus low-dose cisplatin for alpha-fetoprotein-producing gastric carcinoma with liver metastase. Surg Today 2002; 32: 1075-1080
  11. Hirao K, Hirasaki S, Tsuzuki T, Kajiwara T, Hyodo I. Unresectable alpha fetoprotein-producing gastric cancer successfully treated with irinotecan and mitomycin C after S-1 failure. Intern Med 2004; 43: 106-110.