The effect of smoking on the carriage of potential pathogens in nasopharynx

Objective & Hypothesis:Purpose: Smoking is associated with an increased risk of respiratory tract infections in adults and also with oral colonization by some potentially pathogenic microorganisms.

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Key Findings & Data:We evaluated Haemophilus İnfluenza, Moraxella catarrhalis, Streptococcus pneumoniae, Streptococcus pyogenes, Neisseria meningitidis , Staphylococcus aureus and Candida albicans strains.Material and Methods: Study population; 77 healty hospital personel has been selected from several services.

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Conclusion & Impact:We have isolated pathogenic bacteria from 24 of 57 (%42) smokers and 4 of 20 (%20) nonsmokers (p

🔬Design:Research Article

📍Scope:3 specimens

⚙️Variables:Domain Parameters

Abstract

Purpose: Smoking is associated with an increased risk of respiratory tract infections in adults and also with oral colonization by some potentially pathogenic microorganisms. Smoking or passive exposure is enhancing bacterial adherence of pathogenic bacteria to the epithelial cells of the oropharingeal mucous membrane. The aim of this study is to determine the effect of active smoking on colonization of potential aerobic pathogens and in the nasopharynx. We evaluated Haemophilus İnfluenza, Moraxella catarrhalis, Streptococcus pneumoniae, Streptococcus pyogenes, Neisseria meningitidis , Staphylococcus aureus and Candida albicans strains.Material and Methods: Study population; 77 healty hospital personel has been selected from several services. Cultures were obtained using sterile swabs. Specimens collected from the nasopharynx through the mouth. Smokers were classified three groups as: mild smokers (n: 29; 0-10 package/year), moderate (n: 16; 11-20 package/year) and heavy (n: 12; 25+ package/year). Cultures were evaluated with semiquantitative technics (roll plate)Results: We isolated Staphylococcus aureus from 3 specimens, Neisseria meningitidis 1, Acinetobacter lwoffi 1, E.coli 1, intense Candida albicans from 12 specimens, afew mold (Candida albicans ve Candida spp.) from 8 specimens, Haemophilus aphrophilus 1 and Group A ß haemolytic streptococcus from 1 specimen. We have isolated pathogenic bacteria from 24 of 57 (%42) smokers and 4 of 20 (%20) nonsmokers (p

Özet

Amaç: Sigara içiminin solunum yolu enfeksiyonu sıklığını ve bazı potansiyel patojen mikroorganizmaların ağızda kolonizasyonunu artırdığı bilinmektedir. Sigara içiciliği veya sigara dumanına maruz kalmak potansiyel patojen bakterilerin orofaringeal muköz membrana yapışma özelliğini arttırmaktadır. Bu çalışmanın amacı aktif sigara içiminin nazofarinkste potansiyel patojen bakterilerin taşıyıcılığına ve aerob floraya etkisini araştırmaktır. Potansiyel patojen bakteriler olarak Haemophilus İnfluenza, Moraxella catarrhalis, Streptococcus pneumoniae, Streptococcus pyogenes, Neisseria meningitidis , Staphylococcus aureus ve Candida albicans araştırılmıştır.Gereç ve Yöntem: Hastanenin çeşitli servislerinden 77 hastane personeli sağlıklı yetişkin üzeride çalışıldı. Nazofarinks kültürleri steril pamuklu eküvyon ile ağızdan girilerek nasofarinksden alındı. Sigara içenler hafif (n: 29; 0-10 paket/yıl), orta (n: 16; 11-20paket/yıl) ve ağır içici (n: 12; 25 ve üstü paket/yıl) olarak sınıflandırıldı. Kültürler semikantitatif (roll plate,yuvarlama) ekildi ve değerlendirildi.Bulgular: Üç örnekte Staphylococcus aureus, 1 örnekte Neisseria meningitidis, 1 örnekte Acinetobacter lwoffi, 1 örnekte E.coli, 12 örnekte her plak alanında yoğun maya (Candida albicans), 8 örnekte her plak alanında az sayıda maya (Candida albicans ve Candida spp.), 1 örnekte Haemophilus aphrophilus ve 1 örnekte A grubu ß hemolitik streptokok üredi. Elli yedi gönüllü (%75) sigara içiyordu. Sigara içenlerin 24'ünde (%42), sigara içmeyenlerin 4'ünde (%20) patojen bakteri izole edildi (p

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Cite This Article

YETKİN, G., GÜÇLÜER, N., YETKİN, Ö., AY, S., TAŞTEKİN, N. (2022). The effect of smoking on the carriage of potential pathogens in nasopharynx. Erciyes Tıp Dergisi, Cilt: 32 - Sayı: 1, 9–14. https://ajindex.com/articles/502544

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