Journals / Erciyes Tıp Dergisi / 2011 / Cilt: 33 - Sayı: 3

Metabolic syndrome in bipolar affective disorder

İki uçlu duygudurum bozukluğunda metabolik sendrom sıklığı

Pages
197–204
Publication Date
2022-10-17
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It may be concluded that bipolar disorder itself and the drugs used in the treatment of this disorder may not increase the risk of metabolic syndrome.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Purpose: To compare the prevalences of metabolic syndrome in both patients with bipolar disorder and healthy controls.
📊
Key Findings & Data:Material and Methods: A total of 105 patients with remitted bipolar disorder, 59 females and 46 males, and 20 healthy subjects were enrolled to the study.
💡
Conclusion & Impact:It may be concluded that bipolar disorder itself and the drugs used in the treatment of this disorder may not increase the risk of metabolic syndrome.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To compare the prevalences of metabolic syndrome in both patients with bipolar disorder and healthy controls. Material and Methods: A total of 105 patients with remitted bipolar disorder, 59 females and 46 males, and 20 healthy subjects were enrolled to the study. Metabolic syndrome was screened according to the Adult Treatment Protocol of the National Cholesterol Education Program III criteria.Results: Metabolic syndrome was determined in 29.5% of patients and 20% of controls. There was metabolic syndrome in 16 (27%) of 59 female patients and 15 (32%) of 46 male patients. There were no important differences between the patients and controls in regards to the prevalence of metabolic syndrome. There were no significant relationship between gender and the prevalence of metabolic syndrome in patients with bipolar disorder.Conclusion: It has been found that there was a higher rate of metabolic syndrome in patients with bipolar disorder than in controls, but this difference was not statistically important. It may be concluded that bipolar disorder itself and the drugs used in the treatment of this disorder may not increase the risk of metabolic syndrome. Considering the gender distribution,there were no significant difference for the prevalence of metabolic syndrome.

Özet

Amaç: Bu çalışmada iki uçlu bozuklukta metabolik sendrom sıklığının sağlıklı kontrollerle karşılaştırılması amaçlanmıştır. Gereç ve Yöntemler: Çalışmaya remisyonda olan, 59'u kadın, 46'sı erkek olmak üzere 105 iki uçlu duygudurum bozukluklu hasta alındı. Metabolik sendrom NCEP ATP III (Adult Treatment Protocol of the National Cholesterol Education Program) ölçütlerine göre tarandı.Bulgular: Hastaların %29.5'inde ve kontrollerin %20'sinde metabolik sendrom görüldü. 59 kadın hastanın 16'sında (%27) ve 46 erkek hastanın 15'inde (%32) saptandı. Hasta ve kontroller arasında metabolik sendrom sıklığı açısından anlamlı bir fark bulunamadı. Hastalarda cinsiyet ve metabolik sendrom sıklığı arasında anlamlı bir ilişki bulunamadı.Sonuç: Hastalarda kontrollere göre daha yüksek oranda metabolik sendrom saptandı ancak bu fark istatistiksel olarak anlamlı değildi. İki uçlu duygudurum bozukluğu ve bu hastalıkta kullanılan ilaçların metabolik sendrom açısından riski artırmadığı düşünülebilir. Cinsiyetler arasında metabolik sendrom sıklığı açısından fark yoktu.

🔖

Cite This Article

BEŞİRLİ, A., TURAN, M. T., YILDIZ, B. (2022). Metabolic syndrome in bipolar affective disorder. Erciyes Tıp Dergisi, Cilt: 33 - Sayı: 3, 197–204. https://ajindex.com/articles/502518

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Işık E. Depresyon ve Bipolar Bozukluklar 1. baskı, Görsel Sanatlar Yayınevi, s:467–483, 2003
  2. Kaplan HI, Sadock BJ. Klinik Psikiyatri (Çeviri. Hamdullah Aydın, Ali Bozkurt, editörler). 2005. s.1559
  3. Amerikan Psikiyatri Birliği: Ruhsal Bozuklukların Tanısal ve Sayımsal Elkitabı (Çeviri. Ertuğrul Köroğlu), Hekimler Yayın Birliği, Ankara, 2007
  4. Toalson P, Ahmed S, Hardy T, Kobinoff G. The metabolic syndrome in patients with severe mental illnesses. Prim Care Companion J Clin Psychiatry 2004; 6(4):152–158
  5. Özbakkaloğlu M, Demirci C. Yüzyılın salgını: Metabolik sendrom. SSK Tepecik Hastanesi Dergisi 2003;13(3):121–127
  6. Aytekin O. Diabetes Mellitus ve Aterosskleroz. In: Mustafa Yenigün, editör. Her Yönüyle Diabetes Mellitus (2. baskı). Nobel Tıp Kitapevi, İstanbul 2001. s.697–791
  7. Festa A, D'Agostino R Jr, Howard G, Mykkänen L, Tracy RP, Haffner SM. Chronic subclinical inflammation as part of the insulin resistance syndrome: the Insulin Resistance Atherosclerosis Study (IRAS). Circulation 2000;102(1):42–47
  8. Heiskanen T, Niskanen L, Lyytikäinen R, Saarinen PI, Hintikka J. Metabolic syndrome in patients with schizophrenia. J Clin Psychiatry 2003;64 (5):575–579
  9. Casey DE. Metabolic issues and cardiovasculer disease in patients with psychiatric disorders. Am J Med. 2005; 118 Suppl 2:15-22
  10. Ford ES, Giles WH, Mokdad AH. Increasing Prevalence of of the metabolic syndrome among U.S. adults. Diabetes Care 2004; 27(10):2444–2449
  11. Bo S, Cicone G, Pearce N, et al. Prevalence of undiagnosed metabolic syndrome in a population of adult asymptomatic subjects. Diabetes Res Clin Pract 2007; 75(3):362–365
  12. Kozan O, Oguz A, Abaci A, et al. Prevalence of the metabolic syndrome among Turkish adults. Eur J Clin Nutr. 2007;61(4):548–553
  13. Onat A, Sansoy V. Halkımızda koroner hastalığın başsuçlusu metabolik sendrom: sıklığı unsurları, koroner risk ile ilişkisi ve yüksek risk kriterleri. Türk Kardiyoli Derneği Arşivi 2002;30 (1): 8-15
  14. Sanisoğlu SY, Öktenli C, Hasimi A, Yokusoglu M, Ugurlu M. Prevalence of metabolic syndrome–related disorders in a large adult population in Turkey. BMC Public Health 2006; 6: 92
  15. Fagiolini A. Frank E. Houck PR, el al. Prevalence of obesity and weight change during treatment in patients with bipolar I disorder. J Clin Psychiatry 2002; 63(6): 528–533
  16. Elmslie JL, Silverstone JT. Mann JI, Williams SM, Romans SE. Prevalence of overweight and obesity in bipolar patients. J Clin Psychiatry 2000; 61(3): 179–1