Journals / Erciyes Tıp Dergisi / 2014 / Cilt: 36 - Sayı: 2

Kocaeli ilinin içinde ve çevresinde Henoch-Schönlein purpuralı çocukların retrospektif değerlendirilmesi ve literatür ile karşılaştırılması

Retrospective assessment of Children with Henoch-Schonlein purpura in and around Kocaeli province and comparison with literature

Pages
62–67
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In parallel to the literature, the present study showed an increased risk of kidneyinvolvement with increasing age.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim of this retrospective study was to evaluate demographic, etiologic and epidemiologic characteristics, andclinical and laboratory fndings of Henoch-Schonlein purpura (HSP) and to determine risk factors increasing the kidney involvement in our region.
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Key Findings & Data:Materials and Methods: Records of 151 patients who were followed-up with the diagnosis of HSP between May 2002 andDecember 2010 in the Department of Child Nephrology in Kocaeli University Medical Faculty and fulflled the inclusion criteriawere retrospectively evaluated.
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Conclusion & Impact:In parallel to the literature, the present study showed an increased risk of kidneyinvolvement with increasing age.
🔬Design:Research Article
📍Scope:2002 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: The aim of this retrospective study was to evaluate demographic, etiologic and epidemiologic characteristics, andclinical and laboratory fndings of Henoch-Schonlein purpura (HSP) and to determine risk factors increasing the kidney involvement in our region. Materials and Methods: Records of 151 patients who were followed-up with the diagnosis of HSP between May 2002 andDecember 2010 in the Department of Child Nephrology in Kocaeli University Medical Faculty and fulflled the inclusion criteriawere retrospectively evaluated. Demographic characteristics of the patients, season of presentation, complaints on admission,triggering factors, pathological examination, laboratory data, and the duration of follow-up periods were assessed. Results: Of 151 patients, 90 (60%) were male and 61 (40%) were female. The mean age was 7.4±3.4 years (range, 1.8-16.5years). While 33 (22%) patients did not have purpuric rash on admission, they were then observed to have purpuric rash during the follow-ups. Increasing age was found to be a risk factor for kidney involvement (p=0.011). Testicular involvement wasidentifed as a negative risk factor for kidney involvement (p=0.020). Factors such as gender, GIS and musculoskeletal systeminvolvement, recurrence, and steroid treatment were not found to be associated with kidney involvement. Conclusion: Etiologic, epidemiologic, and clinical fndings of HSP patients in our region were found to be similar to those reported in the national and international studies. In parallel to the literature, the present study showed an increased risk of kidneyinvolvement with increasing age.

Özet

Amaç: Bu retrospektif çalışmanın amacı, Henoch-Schönlein purpurası (HSP)nın demografik, etiyolojik ve epidemiyolojik özelliklerini, klinik ve laboratuvar bulgularını değerlendirmek ve bölgemizde böbrek tutulumunu artıran risk faktörlerini belirlemekti. Materyal ve Metot: Kocaeli Üniversitesi Tıp Fakültesi Çocuk Nefroloji Departmanında Mayıs 2002 ve Aralık 2010 arasında HSP tanısı ile takip edilen ve dahil edilme kriterlerini karşılayan 151 hastanın kayıtları retrospektif olarak değerlendirildi. Hastaların demografik özellikleri, başvuru mevsimi, başvuru şikayetleri, tetikleyici faktörler, patolojik muayene, laboratuvar verileri ve takip periyodunun süresi değerlendirildi. Bulgular: 151 hastanın, 90ı (%60) erkek ve 61i (%40) kadındı. Yaş ortalaması 7.4±3.4 yıl (aralık 1.8-16.5 yıl) idi. Başvuruda 33 (%22) hastada purpurik döküntü yok iken, daha sonra takipleri sırasında purpurik döküntüleri olduğu gözlendi. Artan yaş, böbrek tutulumu için bir risk faktörü olarak bulundu (p=0.011). Testis tutulumu, böbrek tutulumu için negatif bir risk faktörü olarak tanımlandı (p=0.020). Cinsiyet, GİS ve kas-iskelet sistemi tutulumu, rekürrens ve steroid tedavisi gibi faktörler böbrek tutulumu ile ilişkili bulunmadı. Sonuç: Bölgemizde HSP hastalarındaki etiyolojik, epidemiyolojik ve klinik bulguların, ulusal ve uluslararası çalışmalarda bildirilenlere benzer olduğu bulundu. Literatüre paralel olarak, bu çalışma artan yaşla ile birlikte böbrek tutulumu riskinin arttığını gösterdi.

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Cite This Article

YILMAZ, A., AYTAÇ, M. B., EKİNCİ, Z. (2022). Kocaeli ilinin içinde ve çevresinde Henoch-Schönlein purpuralı çocukların retrospektif değerlendirilmesi ve literatür ile karşılaştırılması. Erciyes Tıp Dergisi, Cilt: 36 - Sayı: 2, 62–67. https://ajindex.com/articles/502346

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