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Journals / Erciyes Medical Journal / 2022 / Cilt: 44 - Sayı: 2

Potential Use of Integrated Multimodality Imaging ${}^{18}F$-FDG PET-CT in the Evaluation of Inflammatory Bowel Disease: A Brief Report

Abdul Jalil NORDIN
Shazreen SHAHARUDDIN
Fathinul Fikri Ahmad SAAD
Pages
225–228
Publication Date
2022-10-11
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The sensitivity and negative predictive value of ${}^{18}F$-FDG PET-CT were 100%. ${}^{18}F$-FDG PET-CT is a promising, noninvasive method that complements endoscopy in the investigation of IBD and may perhaps play a role as a gatekeeper.

📌 3 Key Takeaways

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Objective & Hypothesis:Inflammatory bowel disease (IBD) significantly increases the risk of colorectal cancer (CRC) due to an inappropriate, aberrant response of the mucosal immune system that can cause chronic irritation and malignant transformation.
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Key Findings & Data:This prospective study included 8 patients who presented at the Gastroenterology Clinic of Serdang Hospital in Malaysia with a prolonged history of altered bowel habits.
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Conclusion & Impact:The sensitivity and negative predictive value of ${}^{18}F$-FDG PET-CT were 100%. ${}^{18}F$-FDG PET-CT is a promising, noninvasive method that complements endoscopy in the investigation of IBD and may perhaps play a role as a gatekeeper.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Inflammatory bowel disease (IBD) significantly increases the risk of colorectal cancer (CRC) due to an inappropriate, aberrant response of the mucosal immune system that can cause chronic irritation and malignant transformation. This prospective study included 8 patients who presented at the Gastroenterology Clinic of Serdang Hospital in Malaysia with a prolonged history of altered bowel habits. Blood tests, endoscopy, tissue biopsy, and whole-body positron emission tomography-computed tomography (PET-CT) using fluorodeoxyglucose F 18 (${}^{18}F$-FDG) as biomarker for tumor imaging were performed. There was a correlation between a high maximum standardized uptake value with contrast-enhanced CT changes, endoscopic, and erythrocyte sedimentation rate findings and clinical presentation. The sensitivity and negative predictive value of ${}^{18}F$-FDG PET-CT were 100%. ${}^{18}F$-FDG PET-CT is a promising, noninvasive method that complements endoscopy in the investigation of IBD and may perhaps play a role as a gatekeeper.

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Cite This Article

NORDIN, A. J., SHAHARUDDIN, S., SAAD, F. F. A. (2022). Potential Use of Integrated Multimodality Imaging ${}^{18}F$-FDG PET-CT in the Evaluation of Inflammatory Bowel Disease: A Brief Report. Erciyes Medical Journal, Cilt: 44 - Sayı: 2, 225–228. https://ajindex.com/articles/502171

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