Journals / Erciyes Medical Journal / 2022 / Cilt: 44 - Sayı: 2

Evaluation of Non-intensive Care Unit-Acquired Sepsis and Septic Shock Patients in Intensive Care Unit Outcomes

Pages
161–166
Publication Date
2022-10-11
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The need for vasopressor drugs or mechanical ventilation was an independent risk factor for mortality.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Sepsis is a clinical condition that requires urgent treatment.
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Key Findings & Data:There is a high mortality rate.
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Conclusion & Impact:The need for vasopressor drugs or mechanical ventilation was an independent risk factor for mortality.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Sepsis is a clinical condition that requires urgent treatment. Most patients with sepsis require intensive care. There is a high mortality rate. The primary aim of the present study was to examine risk factors for mortality in patients with sepsis or septic shock in a medical intensive care unit (ICU). The secondary objective was to analyze the demographic and clinical characteristics of these patients. Materials and Methods: This prospective study was conducted in a medical ICU. Patients diagnosed with sepsis according to the international consensus definition (Sepsis-3) and requiring ICU treatment were included in the study. Demographic and clinical characteristics were recorded and analyzed. Results: A total of 134 patients with sepsis were enrolled in the study. The mean age was 60±18 years and 49% were male. The most frequent reasons for admission to the ICU were respiratory failure (45.5%) and shock (44%). Gram-negative bacteria were present in 48%, Gram-positive bacteria in 15%, fungus in 8%, and there was no culture positivity in 29% of the patients. The in-hospital mortality rate was 51%. The need for vasopressor drugs (odds ratio [OR]: 4.612, 95% confidence interval [CI]: 1.273–16.781) or mechanical ventilation (OR: 25.312, 95% CI: 4.225–151.852) was an independent risk factor for mortality. Conclusion: Patients treated in the ICU for sepsis or septic shock had a high mortality rate. The need for vasopressor drugs or mechanical ventilation was an independent risk factor for mortality.

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Cite This Article

ONUK, S., BULUT, K., DİRİK, H., GÜNDOĞAN, K., SUNGUR, M., SİPAHİOĞLU, H. (2022). Evaluation of Non-intensive Care Unit-Acquired Sepsis and Septic Shock Patients in Intensive Care Unit Outcomes. Erciyes Medical Journal, Cilt: 44 - Sayı: 2, 161–166. https://ajindex.com/articles/502166

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References (13)

  1. Prescott HC, Osterholzer JJ, Langa KM, Angus DC, Iwashyna TJ. Late mortality after sepsis: propensity matched cohort study. BMJ 2016; 353: i2375
  2. Winters BD, Eberlein M, Leung J, Needham DM, Pronovost PJ, Sevransky JE. Long-term mortality and quality of life in sepsis: a systematic review. Crit Care Med 2010; 38(5): 1276–83
  3. Weycker D, Akhras KS, Edelsberg J, Angus DC, Oster G. Long-term mortality and medical care charges in patients with severe sepsis. Crit Care Med 2003; 31(9): 2316–23
  4. Wunsch H, Angus DC, Harrison DA, Linde-Zwirble WT, Rowan KM. Comparison of medical admissions to intensive care units in the United States and United Kingdom. Am J Respir Crit Care Med 2011; 183(12): 1666–73
  5. Vincent JL, Sakr Y, Sprung CL, Ranieri VM, Reinhart K, Gerlach H, et al; Sepsis Occurrence in Acutely Ill Patients Investigators. Sepsis in European intensive care units: results of the SOAP study. Crit Care Med 2006; 34(2): 344–53
  6. Stevenson EK, Rubenstein AR, Radin GT, Wiener RS, Walkey AJ. Two decades of mortality trends among patients with severe sepsis: a comparative meta-analysis*. Crit Care Med 2014; 42(3): 625–31
  7. Rhee C, Dantes R, Epstein L, Murphy DJ, Seymour CW, Iwashyna TJ, et al; CDC Prevention Epicenter Program. Incidence and trends of sepsis in US hospitals using clinical vs claims data, 2009-2014. JAMA 2017; 318(13): 1241–9
  8. Rhee C, Kadri S, Huang SS, Murphy MV, Li L, Platt R, et al. Objective sepsis surveillance using electronic clinical data. Infect Control Hosp Epidemiol 2016; 37(2): 163–71
  9. Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, Ferrer R, et al. Surviving sepsis campaign: International guidelines for management of sepsis and septic shock: 2016. Crit Care Med 2017; 45(3): 486–552
  10. Khwaja A. KDIGO clinical practice guidelines for acute kidney injury. Nephron Clin Pract 2012; 120(4):c179–84
  11. Ferguson ND, Fan E, Camporota L, Antonelli M, Anzueto A, Beale R, et al. The Berlin definition of ARDS: an expanded rationale, justification, and supplementary material. Intensive Care Med 2012; 38(10): 1573–82
  12. Bracht H, Hafner S, Weiss M. Sepsis Update: Definition and epidemiology. [Article in German]. Anasthesiol Intensivmed Notfallmed Schmerzther 2019; 54(1): 10–20
  13. Vallés J, Palomar M, Alvárez-Lerma F, Rello J, Blanco A, GarnachoMontero J, et al; GTEI/SEMICYUC Working Group on Bacteremia. Evolution over a 15-year period of clinical characteristics and outcomes of critically ill patients with c