No bleeding or thromboembolism was observed in any of the 5 patients.
📌 3 Key Takeaways
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Objective & Hypothesis:Factor VII deficiency is a rare condition characterized by a broad spectrum of clinical phenotypes, from asymptomatic status to severe, life-threatening bleeding, such as central nervous system or gastrointestinal bleeding.
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Key Findings & Data:Importantly, bleeding may also occur in patients with a factor level of 20% to 50%.
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Conclusion & Impact:No bleeding or thromboembolism was observed in any of the 5 patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
Factor VII deficiency is a rare condition characterized by a broad spectrum of clinical phenotypes, from asymptomatic status to severe, life-threatening bleeding, such as central nervous system or gastrointestinal bleeding. Factor VII deficiency is usually diagnosed after a bleeding attack or as a result of screening tests performed in cases with a family history. Importantly, bleeding may also occur in patients with a factor level of 20% to 50%. This report describes the approach to management before, during, and after surgery used in 5 patients with varying factor levels. The use of recombinant factor VIIa (15–30 μg kg) was required in 3 of the patients. No bleeding or thromboembolism was observed in any of the 5 patients.
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Cite This Article
ÜMİT, E. G., KIRKIZLAR, H. O., DEMİR, A. M., GÜLSARAN, S. K., DEMİRCİ, U., BAŞ, V. (2022). Management of Patients with Factor VII Deficiency in Surgery: A Single-center Experience. Erciyes Medical Journal, Cilt: 44 - Sayı: 2, 222–224. https://ajindex.com/articles/502156
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