Journals / Erciyes Medical Journal / 2022 / Cilt: 44 - Sayı: 1

Management of Acute Kidney Injury in a Patient with Diabetic Ketoacidosis and Multiple Autoimmune Diseases

Pages
102–105
Publication Date
2022-10-11
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: In addition to classic causes of renal failure in patients with diabetes, it is important to remember the potential effects of other underlying autoimmune events, such as hypothyroidism.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background: Type 1 diabetes mellitus (DM) is an autoimmune disease caused by the failure of pancreatic beta cells to secrete sufficient insulin.
📊
Key Findings & Data:Several other autoimmune diseases that involve the endocrine glands may accompany type 1 DM.
💡
Conclusion & Impact:Conclusion: In addition to classic causes of renal failure in patients with diabetes, it is important to remember the potential effects of other underlying autoimmune events, such as hypothyroidism.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background: Type 1 diabetes mellitus (DM) is an autoimmune disease caused by the failure of pancreatic beta cells to secrete sufficient insulin. Several other autoimmune diseases that involve the endocrine glands may accompany type 1 DM. Prerenal acute kidney injury due to dehydration occurring during diabetic ketoacidosis (DKA) is a common condition that usually improves with appropriate fluid therapy management. Case Report: A 9-year-old child presented with DKA and renal failure that was resistant to treatment. Other autoimmune conditions potentially accompanying the DM were investigated and it was determined that the patient had severe hypothyroidism due to Hashimoto’s thyroiditis. The hypothyroidism was the cause of the treatment-resistant renal failure, which regressed within days of starting levothyroxine treatment. Conclusion: In addition to classic causes of renal failure in patients with diabetes, it is important to remember the potential effects of other underlying autoimmune events, such as hypothyroidism.

🔖

Cite This Article

SARIKAYA, E., DİREK, G., HATİPOĞLU, N., ÖZSOYLU, S., DURSUN, İ. (2022). Management of Acute Kidney Injury in a Patient with Diabetic Ketoacidosis and Multiple Autoimmune Diseases. Erciyes Medical Journal, Cilt: 44 - Sayı: 1, 102–105. https://ajindex.com/articles/502134

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (10)

  1. Norris JM, Johnson RK, Stene LC. Type 1 diabetes-early life origins and changing epidemiology. Lancet Diabetes Endocrinol 2020; 8(3): 226–38
  2. Yang W, Sheng F. Factors associated with thyroid dysfunction in children with newly diagnosed type 1 diabetes mellitus. Minerva Pediatr (Torino) 2021; 73(4): 324–9
  3. Baalaaji M, Jayashree M, Nallasamy K, Singhi S, Bansal A. Predictors and outcome of acute kidney injury in children with diabetic ketoacidosis. Indian Pediatr 2018; 55(4): 311–4
  4. Hursh BE, Ronsley R, Islam N, Mammen C, Panagiotopoulos C. Acute kidney injury in children with type 1 diabetes hospitalized for diabetic ketoacidosis. JAMA Pediatr 2017; 171(5): e170020
  5. Choy J, Yaxley J, Yaxley W. A Rare case of renal impairment caused by primary hypothyroidism. Korean J Fam Med 2018; 39(3): 204–6
  6. Peringat J, Manappallil RG, Karadan U. Rhabdomyolysis: a rare complication of Hashimoto’s thyroiditis precipitated by statin therapy. BMJ Case Rep 2018; 2018: bcr2017223229
  7. Lin H, Wu K, Zhang W, Lin G, Cai C. Evans syndrome with acute kidney injury. Arch Iran Med 2019; 22(6): 336–9
  8. Zhu Z, Chen H, Gill R, Wang J, Spitalewitz S, Gotlieb V. Diabetic ketoacidosis presenting with atypical hemolytic uremic syndrome associated with a variant of complement factor B in an adult: a case report. J Med Case Rep 2016; 10: 38
  9. Alizadeh F, O’Halloran A, Alghamdi A, Chen C, Trissal M, Traum A, et al. Toddler with new onset diabetes and atypical hemolytic-uremic syndrome in the setting of COVID-19. Pediatrics 2021; 147(2): e2020016774
  10. Valenzise M, Aversa T, Saccomanno A, De Luca F, Salzano G. Epidemiological and clinical peculiarities of polyglandular syndrome type 3 in pediatric age. Ital J Pediatr 2017; 43(1): 69.