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Journals / Erciyes Medical Journal / 2022 / Cilt: 44 - Sayı: 3

Evaluation of Monocyte to High-Density Lipoprotein Cholesterol and Neutrophil to High-Density Lipoprotein Cholesterol Ratios as Indicators of Inflammation in Patients with Celiac Disease

Tolga DÜZENLİ
Derya KÖSEOĞLU
Hüseyin KÖSEOĞLU
Pages
274–278
Publication Date
2022-10-11
DOI
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Results: The MHR and the NHR were both high in the study participants with CD (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Celiac disease (CD) is an autoimmune disease with multisystemic manifestations that may be consequences of autoimmunity, inflammation, or malabsorption.
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Key Findings & Data:Materials and Methods: This cross-sectional, retrospective study included 153 participants.
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Conclusion & Impact:Results: The MHR and the NHR were both high in the study participants with CD (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Celiac disease (CD) is an autoimmune disease with multisystemic manifestations that may be consequences of autoimmunity, inflammation, or malabsorption. The monocyte to high-density lipoprotein cholesterol ratio (MHR) and the neutrophil to high-density lipoprotein cholesterol ratio (NHR) are recent markers of inflammation. The aim of the present study was to analyze the relationship between the MHR, NHR, and CD and to examine whether these measures might be used as inflammatory markers in CD. Materials and Methods: This cross-sectional, retrospective study included 153 participants. The data of 50 patients with CD and 103 healthy individuals enrolled as a control group were evaluated. Receiver operating characteristic (ROC) analysis and the corresponding area under the curve (AUC) calculation were performed to assess the discriminatory ability of the MHR and the NHR. Results: The MHR and the NHR were both high in the study participants with CD (p

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Cite This Article

DÜZENLİ, T., KÖSEOĞLU, D., KÖSEOĞLU, H. (2022). Evaluation of Monocyte to High-Density Lipoprotein Cholesterol and Neutrophil to High-Density Lipoprotein Cholesterol Ratios as Indicators of Inflammation in Patients with Celiac Disease. Erciyes Medical Journal, Cilt: 44 - Sayı: 3, 274–278. https://ajindex.com/articles/502121

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References (12)

  1. Lebwohl B, Sanders DS, Green PHR. Coeliac disease. Lancet 2018; 391(10115): 70–81
  2. Avci A, Biricik S, Avci BS, Yesiloglu O, Sumbul HE, Icme F, et al. The new prognostic factor for pulmonary embolism: The ratio of monocyte count to HDL cholesterol. Am J Emerg Med 2021; 46: 212–6
  3. Tani S, Matsumoto M, Anazawa T, Kawamata H, Furuya S, Takahashi H, et al. Development of a model for prediction of coronary atherosclerotic regression: evaluation of high-density lipoprotein cholesterol level and peripheral blood monocyte count. Heart Vessels 2012; 27(2): 143–50
  4. Cetin MS, Ozcan Cetin EH, Kalender E, Aydin S, Topaloglu S, Kisacik HL, et al. Monocyte to HDL cholesterol ratio predicts coronary artery disease severity and future major cardiovascular adverse events in acute coronary syndrome. Heart Lung Circ 2016; 25(11): 1077–86
  5. Kanbay M, Solak Y, Unal HU, Kurt YG, Gok M, Cetinkaya H, et al. Monocyte count/HDL cholesterol ratio and cardiovascular events in patients with chronic kidney disease. Int Urol Nephrol 2014; 46(8): 1619–25
  6. Qi H, Yang S, Zhang L. Neutrophil extracellular traps and endothelial dysfunction in atherosclerosis and thrombosis. Front Immunol 2017; 8: 928
  7. Huang JB, Chen YS, Ji HY, Xie WM, Jiang J, Ran LS, et al. Neutrophil to high-density lipoprotein ratio has a superior prognostic value in elderly patients with acute myocardial infarction: a comparison study. Lipids Health Dis 2020; 19(1): 59
  8. Al-Toma A, Volta U, Auricchio R, Castillejo G, Sanders DS, Cellier C, et al. European Society for the Study of Coeliac Disease (ESsCD) guideline for coeliac disease and other gluten-related disorders. United European Gastroenterol J 2019; 7(5): 583–613
  9. Husby S, Murray JA, Katzka DA. AGA Clinical practice update on diagnosis and monitoring of celiac disease-changing utility of serology and histologic measures: Expert review. Gastroenterology 2019; 156(4): 885–9
  10. Özakıncı H, Kırmızı A, Savaş B, Kalkan Ç, Soykan İ, Çetinkaya H, et al. Classification chaos in coeliac disease: Does it really matter? Pathol Res Pract 2016; 212(12): 1174–8
  11. Karataş MB, Çanga Y, Özcan KS, İpek G, Güngör B, Onuk T, et al. Monocyte to high-density lipoprotein ratio as a new prognostic marker in patients with STEMI undergoing primary percutaneous coronary intervention. Am J Emerg Med 2016; 34(2): 240–4
  12. Raggi P, Genest J, Giles JT, Rayner KJ, Dwivedi G, Beanlands RS, et al. Role of inflammation in the pathogenesis of atherosclerosis and therapeut