Journals / Endoskopi / 2014 / Cilt: 22 - Sayı: 2

Incidentally detected focal colonic involvement in our cases with PET scan

PET incelemede insidental saptanan fokal kolon tutulumu olgularımız

Journal
Endoskopi
Pages
29–32
Publication Date
2022-10-11
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Nevertheless, positron emission tomography/computed tomography has no place in colon cancer screening and surveillance.

📌 3 Key Takeaways

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Objective & Hypothesis:Background and Aims: Recent studies have assessed the ability of positron emission tomography/computed tomography to detect synchronous colonic pathology and determined the significance of fluorodeoxyglucose activity.
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Key Findings & Data:The aim of this case-based study was to assess the performance of fluorodeoxyglucose positron emission tomography/computed tomography for the detection of colonic adenomas.
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Conclusion & Impact:Nevertheless, positron emission tomography/computed tomography has no place in colon cancer screening and surveillance.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background and Aims: Recent studies have assessed the ability of positron emission tomography/computed tomography to detect synchronous colonic pathology and determined the significance of fluorodeoxyglucose activity. Therefore, focal lesions should be followed closely. In our patients with fo- cal involvement, the diagnosis was confirmed by colonoscopy and histopa- thology. The aim of this case-based study was to assess the performance of fluorodeoxyglucose positron emission tomography/computed tomography for the detection of colonic adenomas. Materials and Methods: A total of six random cancer patients who underwent positron emission tomography/ computed tomography and showed intense focal colonic fluorodeoxyglucose uptake were enrolled in this study. The etiology of positron emission tomog- raphyfindings was verified with a subsequent colonoscopy and endoscopic resection. The characteristics of the lesions detected by histopathologic ex- amination are presented. Results: All polyps with fluorodeoxyglucose up- take were >15 mm. Four polyps with high-grade dysplasia were >25 mm in diameter. One of the other polyps measuring 20 mm was determined as tubular adenoma. Another showed low-grade dysplasia and measured 15 mm in diameter. In addition, five adenomatous polyps 6-7 mm in diameter were detected in two cases. There was no dysplasia in these five polyps, and no fluorodeoxyglucose uptake was detected. Conclusions: Presence of a fo- cal colonic fluorodeoxyglucose uptake as an incidental finding on a positron emission tomography/computed tomography scan justifies a colonoscopy. Fluorodeoxyglucose uptake of adenomatous polyps increases in conjunc- tion with the degree of dysplasia and adenoma size. Nevertheless, positron emission tomography/computed tomography has no place in colon cancer screening and surveillance.

Özet

Giriş ve Amaç: Pozitron emisyon tomografi/bilgisayarlı tomografi'nin senkron kolonik lezyonların saptanmasında yeterli olduğu ve kolondaki florodeoksiglukoz tutulumunun önemi son çalışmalarla gösterilmiştir. Bu nedenle başka tanılarla çekilen pozitron emisyon tomografi/bilgisayarlı to- mografi'de saptanan insidental fokal lezyonların sıkı olarak tetkik edilmesi önerilmektedir. Kolonda fokal florodeoksiglukoz tutulumu saptanan hasta- lar da kolonoskopi ve histopatolojik olarak değerlendirilmelidir. Bu çalış- manın amacı florodeoksiglukoz-pozitron emisyon tomografi/bilgisayarlı to- mografi'de insidental fokal kolonik aktivite saptanan ve kolonoskopi yapılan vakalarda eşlik eden kolonik lezyon olup olmadığını ve varlığında karakte- rini dökümante etmektir. Gereç ve Yöntem: Farklı bir malignitenin takibi nedeniyle uygulanan pozitron emisyon tomografi/bilgisayarlı tomografi'de insidental kolonik fokal tutulumu olan toplam 6 olgu çalışmaya dahil edildi. Hastalara pozitron emisyon tomografi/bilgisayarlı tomografi bulgularının eti- yolojisini saptamak için total kolonoskopi yapıldı. Hastalarda saptanan tüm kolonik lezyonlar endoskopik olarak çıkarıldı. Lezyonların karakteri histo- patolojik inceleme ile tespit edildi. Bulgular: Fokal tutuluma neden olan poliplerin tümünün çapı >= 15 mm idi. Yüksek dereceli displazi içeren 4 po- lipin çapı >= 25 mm idi. Diğer poliplerden biri 20 mm çapında olup tübüler adenom, diğeri ise 15 mm çapında olup düşük dereceli displazi saptandı. Tüm olguların ikisinde ek olarak 6-7 mm çapında toplam 5 adet adenomatöz polip saptandı. Bu 5 adet polipin histopatolojik değerlendirmesinde displazi yoktu. Bu poliplere uyan florodeoksiglukoz tutulumu saptanmadı. Sonuç: Pozitron emisyon tomografi/bilgisayarlı tomografi'de insidental kolonik fokal tutulum olan alanlarda adenomatöz polipler saptanabilmektedir. İnsidental tespit edilen fokal hipermetabolik durumlar göz ardı edilmemeli, teyidi ve çıkarılması için kolonoskopi yapılmalıdır. Kolon kanseri taramasında ve sürveyansında pozitron emisyon tomografi/bilgisayarlı tomografi'nin yerini araştıran karşılaştırmalı çalışmalara ihtiyaç vardır.

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Cite This Article

OKUTURLAR, Y., UÇAR, M., SOYLU, A., SEVİNDİR, İ., ÇAKMAK, S. (2022). Incidentally detected focal colonic involvement in our cases with PET scan. Endoskopi, Cilt: 22 - Sayı: 2, 29–32. https://ajindex.com/articles/501134

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