Journals / Endoskopi / 2017 / Cilt: 25 - Sayı: 2

Upper gastrointestinal system involvement of Crohn's disease: Single center experience

Crohn hastalığının üst gastrointestinal sistem tutulumu: Tek merkez deneyimi

Journal
Endoskopi
Pages
13–15
Publication Date
2022-10-11
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Early diagnosis and appropriate treatment are necessary to prevent complications.

📌 3 Key Takeaways

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Objective & Hypothesis:Background and Aims: The frequency of upper gastrointestinal system in- volvement in Crohn's disease is 0.5%-4%.
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Key Findings & Data:Treatment and follow-up strate- gies of these patients differ from those of ileocolonic disease.
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Conclusion & Impact:Early diagnosis and appropriate treatment are necessary to prevent complications.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background and Aims: The frequency of upper gastrointestinal system in- volvement in Crohn's disease is 0.5%-4%. Treatment and follow-up strate- gies of these patients differ from those of ileocolonic disease. Here we pres- ent our patients who had Crohn's disease with upper gastrointestinal system involvement. Materials and Methods: We retrospectively investigated our patients who had Crohn's disease with upper gastrointestinal system involve- ment. Results: Upper gastrointestinal system involvement was detected in 10 patients. The median age of patients was 40.5 years (31-53 years); 6 pa- tients were male and 4 patients were female. The median follow-up period after diagnosis was 29 months. Four patients had isolated upper gastrointestinal system involvement, while 6 patients had ileocolonic disease. The frequency of organ involvement was 10% (1 patient) for the esophagus, 20% (2 patients) for the stomach, and 70% (7 patient) for the duodenum. Endoscopic appearances varies among patients; cobble stone appearances were detected in 2 patients, ulcers were detected in 7 patients and nodulariy were detected in 4 patients. Granulomas were detected histopathologically in 3 patients (30%). Conclusion: Complaints like epigastric pain, nausea and vomiting, and/or dysphagia must warrant clinicians to investigate the upper gastrointestinal system in Crohn's disease. Early diagnosis and appropriate treatment are necessary to prevent complications.

Özet

Giriş ve Amaç: Crohn hastalığı için üst gastrointestinal sistem tutulumu sıklığı %0,5-4 arasında değişir. Bu hastaların tedavi ve takipleri ileokolonik hastalıktan farklılık gösterir. Biz bu çalışmada kliniğimizde Crohn hastalı- ğının üst gastrointestinal sistemi etkilediği hastalarımızı sunduk. Gereç ve Yöntem: Hastanemiz Gastroenteroloji Kliniğinde takip edilen ve üst gast- rointestinal sistem tutulumu olan Crohn hastaları çalışmaya alındı. Bulgu- lar: 10 hastada üst gastrointestinal sistem tutulumu izlendi. Hastaların yaş ortancası 40,5 olup 6 hasta (%60) erkek 4 hasta (%40) ise kadındı. Ortanca takip süresi 29 ay olup hastaların 4 tanesinde (%40) izole üst gastrointestinal sistem tutulumu varken geri kalan 6 hastanın (%60) be- raberinde ileal veya ileokolonik hastalığı vardı. Organ tutulumlarına bakıldı- ğında 1 hastada (%10) özofagus, 2 hastada mide (%20) ve 7 hastada (%70) duodenum tutulumu izlendi. Endoskopik görünümler hastadan hastaya de- ğişmekle beraber Crohn hastalığı için tipik sayılan kaldırım taşı görünümü 2 hastada, ülserler 7 hastada ve nodülarite ise 4 hastada endoskopik olarak tanımlandı. Biyopsilerde granülom 3 hastada izlendi (%30) Sonuç: Crohn hastalığı tanısı olan bir bireyde gelişen epigastrik ağrı, bulantı-kusma ve disfaji gibi şikayetler üst gastrointestinal sistemin endoskopik incelenmesini zorunlu hale getirmektedir. Erken tanı ve uygun tedavi gelişebilecek komp- likasyonların önüne geçebilir.

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Cite This Article

KILIÇ, Z. M. Y., KAPLAN, M., ÖZTÜRK, Ö., KALKAN, İ. H., ÖZİN, Y. Ö., TENLİK, İ., AKPINAR, M. Y., AKDOĞAN, Ö., YÜKSEL, M., KAYAÇETİN, E. (2022). Upper gastrointestinal system involvement of Crohn's disease: Single center experience. Endoskopi, Cilt: 25 - Sayı: 2, 13–15. https://ajindex.com/articles/501070

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