Journals / Endokrinolojide Yönelişler / 2002 / Cilt: 11 - Sayı: 6

The effect of magnesium replacement on electrolyte levels in type II diabetes mellitus

Tip II diabetes mellituslu hastalarda magnezyum replasmanının elektrolit düzeylerine etkisi

Pages
252–256
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In hypomagnesemic and normomagnesemic patients the levels of Mg, Na, K, Ca and P were 1.63(0.24 mg/dl, 2.02(0.15 mg/dl (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:It was shown in many studies that the serum magnesium level was decreased and hypomagnesemia was frequently seen in type II diabetic patients.
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Key Findings & Data:Material-Method: The levels of Mg, Na, Ca, P, HbA1C and glucose of 204 type II diabetic patients were examined in GATA Haydarpaşa Training Hospital.
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Conclusion & Impact:In hypomagnesemic and normomagnesemic patients the levels of Mg, Na, K, Ca and P were 1.63(0.24 mg/dl, 2.02(0.15 mg/dl (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

It was shown in many studies that the serum magnesium level was decreased and hypomagnesemia was frequently seen in type II diabetic patients. It is reported that there was a relationship between hypomagnesemia and serum levels of sodium (Na), potassium (K), calcium (Ca), phosphor (P). We evaluate the effect of magnesium replacement on electrolyte levels. Material-Method: The levels of Mg, Na, Ca, P, HbA1C and glucose of 204 type II diabetic patients were examined in GATA Haydarpaşa Training Hospital. The patients were randomized in two groups and 126 patients were given MgS04 (360 mg/tid 3 months). Results: Hypomagnesemia was found in 41.03% of patients. In hypomagnesemic and normomagnesemic patients the levels of Mg, Na, K, Ca and P were 1.63(0.24 mg/dl, 2.02(0.15 mg/dl (p

Özet

Amaç: Tip II diabetik hastalarda serum magnezyum (Mg) düzeyinin önemli derecede azaldığı ve hipomagnezeminin sık görüldüğü birçok çalışmada gösterilmiştir. Hipomagnezeminin sodyum (Na), potasyum (K), kalsiyum (Ca), fosfor (P) düzeyleri ile ilişkisi olduğu, herhangi birinin eksikliğinde diğerlerinde de kayıp olabileceği bildirilmiştir. Tip II diabetik hastalarda elektrolit düzeylerine Mg replasmanının etkisini değerlendirmek amacıyla bu çalışmayı yaptık. Materyal-Metod: Bu amaçla GATA Haydarpaşa Eğitim Hastanesi Endokrinoloji kliniğinde böbrek fonksiyonları sağlam, 204 tip II diabetik hastanın Mg, Na, K, Ca, P, glikozile hemoglobin (HbA1c) ve glisemi düzeyleri ölçüldü. Hastalar rastgele iki gruba ayrıldı ve 126 hastaya üç ay süre ile 3±360 mg MgS04 verildi. Bulgular: Hastaların %41.03'ünde hipomagnezemi saptandı. Hipomagnezemik ve normomagnezemik hastalarda Mg, Na, K, Ca ve P düzeyleri sırasıyla 1.63±0.24 mg/dl, 2.02±0.15 mg/dl (p

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Cite This Article

HAKSEVER, N., TOR, H., GÖZAYDIN, M., SEZER, M. (2022). The effect of magnesium replacement on electrolyte levels in type II diabetes mellitus. Endokrinolojide Yönelişler, Cilt: 11 - Sayı: 6, 252–256. https://ajindex.com/articles/500937

References (15)

  1. Arieff Âl: Kidney, water and electrolyte metabolism in diabetes mellitus. The Kidney. (Eds) Brenner BM, Rector FCrPhiladelphia, PA. W.B. Sounders: 1976, 1257-1296
  2. Pun KK, Ho PWM: Subclinical hyponatremia, hypercalemia and hypo- magnesemia in patients with poorly controled diabetes mellitus. Diabetes Research and Clinical Practice 7:163-167,1989
  3. Schnack Ch, Bauer I, Pregant P, Hopmeier P, Schernthaner G: Hypo- magnesemia in type II non insulin dependent diabetes mellitus is not corrected by improvement of long-term metabolic control. Diabetolo- gia, 35(D:77-79,1992
  4. Corica F, Allegra A, Giacobbe MS, Ceruso D:The role of magnesium in glucose homeostatis: therapeutic implications (AbsctracO.Clin Ter 143 (1):45-55,1993
  5. White Jr JR, Campbell RK: Magnesium and diabetes: a review. The annals of pharmacotherapy 27:775-780,1993
  6. Alfrey A, Miller N, Butkus D. Evaluation of body magnesium stores. J Lab Clin Med, 84:153-162,1974
  7. Knochel JP: Disorders of magnesium metabolism. Harrison's principles of internal medicine. (Eds) Wilson JD, Braunwald E, Isselbacher KJ, Petersdorf RG, Martin JB, Fauci AS, Root RK: 12th Ed. Vol.2: New York Me Graw-Hill Inc.:1991,1935-1938
  8. Resnick LM, Altura BT, Gupta RK, Laragh JH, Alderman MH, Altura MM: Intracellular and extracellular magnesium depletion in type 2 diabetes mellitus. Diabetologia 36:767-770,1993- 9. Shils M:Experimental human magnesium depletion. Medicine. 48:61- 85,1969
  9. Sjögren A, Flören C-H, Nilsson A: Magnesium deficiency in IDDM related to level of glycosylated hemoglobin. Diabetes 35:459-463,1986
  10. Reinhart RA: Magnesium metabolism: A review with special reference to the relationship between intracellular content and serum levels. Arch Intern Med 148:2415-2420,1988
  11. Hayran N, Özdemir O: Bilgisayar İstatistik ve Tıp. Hekimler Yayın Birliği. Medikal Araştırma Birimi., Ankara, 1995
  12. Fujii S, Takemura T, Wada M, Akai T, Okuda K: Magnesium levels in plasma, erythrocyte and urine in patients with diabetes mellitus. Horm Metab Res., 14:161-162,1982
  13. Levin GE, Mather HM, Pilkington TRE: Tissue magnesium status in diabetes mellitus. Diabetologia 21:131-134,1981
  14. McNair P, Christensen MS, Christiansen C, Madsbad S, Transbol LRenal hypomagnesaemia in human diabetes mellitus:its relation to glucose homeostatis. Eur J Clin Invest, 12:81-85,1982
  15. McNair P, Christiansen C, Madsbad S, Lauritzen E, Faber O, Binder C, Transbol I: Hypomagnesemia, a risk factor in diabetic retinopath