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Journals / Endokrinolojide Yönelişler / 2004 / Cilt: 13 - Sayı: 3

Effects of experimental hypothyroidism on hemorheological parameters

Deneysel hipotiroidinin hemoreolojik parametrelere etkisi

Nuran DARIYERLİ
Selmin TOPLAN
Hüsrev HATEMİ
Günnur YİĞİT
M. Can AKYOLCU
Semra ÖZDEMİR
Pages
83–85
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

According to results of our study when values of control group and experimental groups were compared: While T3 and T4 levels of experimental group were found lower (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Effects of hypothyroid on hemorheology of patients had widely attracted the attention of researchers during last decade.
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Key Findings & Data:To induce experimental hypothyroid methymazole (75mg/100g) was added to the fodder of experimental group rats for 20 days.
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Conclusion & Impact:According to results of our study when values of control group and experimental groups were compared: While T3 and T4 levels of experimental group were found lower (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Effects of hypothyroid on hemorheology of patients had widely attracted the attention of researchers during last decade. Present study has been planned with the purpose to determine the effects of experimental hypothyroidsm on hemorheological parameters and fibrinogen concentration. To induce experimental hypothyroid methymazole (75mg/100g) was added to the fodder of experimental group rats for 20 days. After experimental duration plasma and blood viscosity, hematocrit, hemoglobin, erythrocyte rigidity index and plasma fibrinogen concentration values of both control and experimental group animals were determined and evaluated. According to results of our study when values of control group and experimental groups were compared: While T3 and T4 levels of experimental group were found lower (p

Özet

Çalışmamız deneysel hipotiroidinin hemoreolojik parametreler ve fibrinojen konsantrasyonu üzerine etkisini araştırmak amacıyla planlandı. Araştırmada Spraque-Dawley türü dişi sıçanlar kullanıldı. Deney hayvanları kontrol (n=10) ve deney (n= 10) olmak üzere iki gruba ayrıldı. Deney grubunu oluşturan sıçanlara hipotiroidi oluşturmak üzere yaklaşık yirmi gün süre ile methima-zole verildi (75mg/100g yem). Yirmi gün sonunda kontrol ve deney gruplarından alınan kan örneklerinde plazma ve kan vizkozitesi, Hct, Hb, eritrosit rijiditesi ve plazma fibrinojen konsantrasyonu ölçüldü. Deney gru¬bu sonuçlarını kontrol grubu ile karşılaştırdığımızda T3, T4 düzeyleri anlamlı olarak düşük (p< 0.001), TSH düzeyi ise anlamlı olarak yüksek (p

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Cite This Article

DARIYERLİ, N., TOPLAN, S., HATEMİ, H., YİĞİT, G., AKYOLCU, M. C., ÖZDEMİR, S. (2022). Effects of experimental hypothyroidism on hemorheological parameters. Endokrinolojide Yönelişler, Cilt: 13 - Sayı: 3, 83–85. https://ajindex.com/articles/500870

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