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Journals / Endokrinolojide Yönelişler / 2004 / Cilt: 13 - Sayı: 5

The comparison of the value of combined bone/Ga-67 and bone/Tc-99m HPAO labeled leukocyte scintigraphy in the diagnosis and follow-up of osteomyelitis in diabetic foot ulcers

Diabetik ayak ülserinde kombine kemik/Ga-67 ve kemik/Tc-99m HMPAO lökosit sintigrafilerinin karşılaştırılması

Nazif BAĞRIAÇIK
İlhami USLU
Hüsrev HATEMİ
Tanju Yusuf ERDİL
Kutlan ÖZKER
Mustafa ÖZYAZAR
Çetin ÖNSEL
Halil Turgut TUROĞLU
Pages
160–163
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion, in the diagnosis and follow-up of osteomyelitis in the diabetic foot ulcers, combined bone/leukocyte scan is more valuable than combined bone/Ga-67 scan.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:İn this study, the value of combined bone/Ga-67 and bone/Tc-99m HMPAO labeled leukocyte scintigraphy in the diagnosis and follow-up of osteomyelitis in diabetic foot ulcers was compared.
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Key Findings & Data:Seventeen patients with diabetic foot ulcers were underwent three-phase bone, Tc-99m HMPAO labeled leukocyte and Ga-67 scintigraphy.
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Conclusion & Impact:In conclusion, in the diagnosis and follow-up of osteomyelitis in the diabetic foot ulcers, combined bone/leukocyte scan is more valuable than combined bone/Ga-67 scan.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

İn this study, the value of combined bone/Ga-67 and bone/Tc-99m HMPAO labeled leukocyte scintigraphy in the diagnosis and follow-up of osteomyelitis in diabetic foot ulcers was compared. Seventeen patients with diabetic foot ulcers were underwent three-phase bone, Tc-99m HMPAO labeled leukocyte and Ga-67 scintigraphy. The study was repeated 4-6 weeks after antibiotic treatment in 9 patients.For the 24 ulceration sites, 13 cases of osteomyelitis were diagnosed on the basis of radiology, tissue culture or biopsy and follow-up. The sensitivity, specificity and accuracy were found to be 100 %, 36 % and 70 % for bone scan, 84 %,45 % and 66 % for combined bone/Ga-67 scan, and 92 %, 73 %, and 83 % for combined bone/leukocyte scan, respectively. It was demonstrated that the efficacy of treatment was more accurately shown withleukocyte scan compared with Ga-67. In conclusion, in the diagnosis and follow-up of osteomyelitis in the diabetic foot ulcers, combined bone/leukocyte scan is more valuable than combined bone/Ga-67 scan.

Özet

Bu çalışmada, diyabetik ayak ülserlerinde osteomyelitin tanısı ve takibinde kemik/Ga-67 ve kemik/Tc-99m HMPAO lökosit sintigrafilerinin değeri karşılaştırıldı. Diyabetik ayak ülseri olan 17 hastada, üç fazlı kemik, Tc-99m HMPAO lökosit ve Ga-67 sintigrafileri uygulandı. 9 hastada, çalışma antibiyotik tedavisinden 4-6 hafta sonra tekrarlandı. 24 ayak ülserinden 13'ünde radyoloji, doku kültürü veya doku biyopsisi ve takip ile osteomyelit tanısı kondu. Duyarlılık, özgüllük ve doğruluk değerleri sırası ile kemik sintigrafisi için % 100, % 36, % 70, kemik/Ga-67 sintigrafisi için % 84, % 45, % 66, kemik/lökosit sintigrafisi için % 92, % 73, % 83 olarak bulundu. Tedavinin etkinliğini, lökosit sintigrafisinin Ga-67'e göre daha iyi gösterdiği saptandı. Sonuç olarak, diyabetik ayak ülserlerinde osteomyelit tanısında ve takibinde kombine kemik/işaretli lökosit sintigrafisi, kemik/Ga-67 sintigrafisinden daha değerli bulunmuştur.

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Cite This Article

BAĞRIAÇIK, N., USLU, İ., HATEMİ, H., ERDİL, T. Y., ÖZKER, K., ÖZYAZAR, M., ÖNSEL, Ç., TUROĞLU, H. T. (2022). The comparison of the value of combined bone/Ga-67 and bone/Tc-99m HPAO labeled leukocyte scintigraphy in the diagnosis and follow-up of osteomyelitis in diabetic foot ulcers. Endokrinolojide Yönelişler, Cilt: 13 - Sayı: 5, 160–163. https://ajindex.com/articles/500865

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