Journals / Endokrinolojide Yönelişler / 2004 / Cilt: 13 - Sayı: 2

Comparison of the clinical and laboratory features of idiopathic hirsutismus and polycystic ovary syndrome cases

İdiyopatik hirsutizm ve polikistik over sendromlu olguların klinik ve laboratuvar özelliklerinin karşılaştırılması

Pages
61–63
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

For the evaluation of the severity of hirsutismus all androgen dependent areas should be carefully examined.

📌 3 Key Takeaways

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Objective & Hypothesis:Hirsutismus is a clinical syndrome with a prevalence of 5-15% characterized by the increase in the amount of terminal hair with male type of distribution.
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Key Findings & Data:The aim of this study was to compare the clinical and laboratory features of 75 IH and PCOS cases who were admitted to Endocrinology outpatient clinic in the last 1 year period with the complaint of increased amount of terminal hair.70.7% of the patients were diagnosed as IH and 29.3% as PCOS.
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Conclusion & Impact:For the evaluation of the severity of hirsutismus all androgen dependent areas should be carefully examined.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Hirsutismus is a clinical syndrome with a prevalence of 5-15% characterized by the increase in the amount of terminal hair with male type of distribution. The most frequent etiologic factors are idiopathic hirsutismus (IH) and polycystic ovary syndrome (PCOS). The aim of this study was to compare the clinical and laboratory features of 75 IH and PCOS cases who were admitted to Endocrinology outpatient clinic in the last 1 year period with the complaint of increased amount of terminal hair.70.7% of the patients were diagnosed as IH and 29.3% as PCOS. There was no significant difference among groups concerning age, body mass index, Ferriman-Gallwey score and follicule stimulating hormone levels. Mean serum luteinizing hormone, total and free testosterone levels were significantly lower in IH compared to PCOS cases. In 45.5% of PCOS cases pelvic ultra-sonography revealed bilateral multiple milimetric folli-cules that apted to PCOS. Similar ultrasonographic ap-pearence was detected in 11.3% of IH cases. As a result, laboratory findings and rhythm of menstu-ration cycles are important in the diagnosis of IH and PCOS. Ultrasonographic examination of the ovaries are not diagnostic but support the diagnosis. For the evaluation of the severity of hirsutismus all androgen dependent areas should be carefully examined.

Özet

Hirsutizm, kadınlarda terminal kılların miktarının artışı ve erkek tipi dağılımı ile karakterize klinik bir tablodur. Prevalansı %5-15'tir. En sık görülen nedenleri arasında idiyopatik hirsutizm (IH) ve polikistik over sendromu (PCOS) yer almaktadır.Bu çalışmada son 1 yıllık dönem içerisinde Endokrinoloji polikliniğine kıllanma artışı yakınması ile başvuran IH ve PCOS tanılı 75 hastanın demografik özelliklerinin, klinik ve laboratuvar bulgularının karşılaştırılması amaçlanmıştır.Hastaların %70.7'sinde İH, %29.3'ünde PCOS olduğu saptandı. Guruplar arasında yaş, beden kitle indeksi, Ferriman-Gallwey skoru ve follikül stimülan hormon düzeyleri arasında anlamlı farklılık yoktu. Ortalama serum luteinizan hormon, total ve serbest testosteron değerleri İH gurubunda PCOS gurubuna göre anlamlı düşüktü. Pelvik ultrasonografide PCOS tanısı alan hastaların %45.5'inde PCOS ile uyumlu bilateral multipl milimetrik folliküller saptandı. Benzer ultrasonografik görünüm IH tanısı alan hastaların %11.3'ünde mevcuttu. Sonuç olarak, IH ve PCOS tanısında laboratuvar bulguları ve menstürel siklus düzeni önemlidir. Ultrasonografide överlerin değerlendirilmesi tanıyı desteklemekle birlikte tanı koydurucu değildir. Hirsutizmin derecesinin belirlenmesinde tüm androjene duyarlı bölgelerin dikkatle muayenesi yapılmalıdır.

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Cite This Article

KIYICI, S., ERTÜRK, E., TUNCEL, E., İMAMOĞLU, Ş., DURAN, C., GÖZKAMAN, A., BABACAN, A. N., İMADOĞLU, O., ERSOY, C. (2022). Comparison of the clinical and laboratory features of idiopathic hirsutismus and polycystic ovary syndrome cases. Endokrinolojide Yönelişler, Cilt: 13 - Sayı: 2, 61–63. https://ajindex.com/articles/500850

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