Journals / Endokrinolojide Yönelişler / 2004 / Cilt: 13 - Sayı: 5

The relation between DHEA-S levels and atherosclerosis in postmenopausal women

Postmenopozal kadınlarda DHEA-S seviyeleri ile ateroskleroz arasındaki ilişki

Pages
150–154
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There was not significant difference in DHEA-S levels between hypertensive and normotensive patients.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:DHEA-S is an androgen with 19 carbon cited in the reticulaire layer of the adrenal cortex.
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Key Findings & Data:After menopause, DHEA-S levels decrease significantly like estrogen, but this decrease is milder.
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Conclusion & Impact:There was not significant difference in DHEA-S levels between hypertensive and normotensive patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

DHEA-S is an androgen with 19 carbon cited in the reticulaire layer of the adrenal cortex. Aging causes important endocrine and neuroendocrine physiological changes in men and women. After menopause, DHEA-S levels decrease significantly like estrogen, but this decrease is milder. In this study, the relation between DHEA-S levels and atherosclerosis was evaluated in 57 postmenopausal women (age range: 46-84). The age groups were: 70. DHEA-S levels were signficantly decreased with aging. As the DHEA-S levels decreased, the incidence of ischemic heart disease increased. There was not significant difference in DHEA-S levels between hypertensive and normotensive patients.

Özet

DHEA-S hemen tamamen adrenal korteksin retiküler tabakasında yapılan 19 karbonlu bir androjendir. Erkekler ve kadınlar yaşlanma ile görülen ciddi endokrin ve nöroendokrin fizyolojik değişikliklere uğrarlar. Östrojen gibi DHEA-S seviyeleri de menapozdan sonra daha anlamlı olarak azalmaktadır, yalnız bu azalma östrojene göre daha ılımlı ve derecelidir. Çalışmamızda 57 adet, yaşları 46 ile 84 arasında olan postmenapozal kadında DHEA-S seviyeleri ile ateroskleroz arasındaki ilişkiyi araştırdık. Olgular; 70 yaş olmak üzere üçe ayrıldı. Sonuçta DHEA-S seviyeleri yaş ile anlamlı ölçüde azalmış ve DHEA-S seviyeleri azaldıkça iskemik kalp hastalığı görülme oranını anlamlı olarak artmış tespit ettik. Hipertansiyonu olan olguların DHEA-S düzeyleri ile hipertansiyonu bulunmayan olgular arasında anlamlı bir fark bulunmadı.

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Cite This Article

SÜT, N., DÖVENTAŞ, A., KARADAĞ, B., BEĞER, T., BOLAYIRLI, İ. M., BİLİCİ, A., ÇURGUNLU, A. (2022). The relation between DHEA-S levels and atherosclerosis in postmenopausal women. Endokrinolojide Yönelişler, Cilt: 13 - Sayı: 5, 150–154. https://ajindex.com/articles/500847

References (1)

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