Journals / Endokrinolojide Diyalog Dergisi / 2009 / Cilt: 6 - Sayı: 1

Hypocalcaemia after thyroidectomy for thyrotoxicosis

Hipertiroidi nedeniyle yapılan tiroidektomi sonrası hipokalsemi

Pages
33–37
Publication Date
2022-10-11
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It often extends the duration of the hospital stay and the need for biochemical tests, and it significantly increases the overall cost of a thyroidectomy We retrospectively evaluated the incidence of hypocalcemia and permanent hypoparathyroidism following thyroidectomy in 111 patients operated between 2003-2007.

📌 3 Key Takeaways

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Objective & Hypothesis:Postoperative hypocalcemia is a common and most often transient event after thyroid surgery.
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Key Findings & Data:It often extends the duration of the hospital stay and the need for biochemical tests, and it significantly increases the overall cost of a thyroidectomy We retrospectively evaluated the incidence of hypocalcemia and permanent hypoparathyroidism following thyroidectomy in 111 patients operated between 2003-2007.
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Conclusion & Impact:Antithyroid medication should reverse osteodystrophy before operation, this reversal takes up to weeks, whereas most our patients were prepared for a much shorter period.
🔬Design:Research Article
📍Scope:2003-2007 Verileri
⚙️Variables:Domain Parameters

Abstract

Postoperative hypocalcemia is a common and most often transient event after thyroid surgery. It often extends the duration of the hospital stay and the need for biochemical tests, and it significantly increases the overall cost of a thyroidectomy We retrospectively evaluated the incidence of hypocalcemia and permanent hypoparathyroidism following thyroidectomy in 111 patients operated between 2003-2007. We determined in study which early clinical and biochemical characteristics of patients experiencing postoperative hypocalcemia correlated with the long-term outcome. Postoperative calcemia under 8mg/dl was observed in 44 patients (39.6%). In 10 patients hypocalcemia was considered severe (symptomatic). At 6 months after surgery three patients (2.7%) had persistent hypocalcemia. We found that patients carried a high risk for transient hypocalcemia was significantly higher in thyrotoxic patients (p=0031). Hypoparathyroidism could not account for hypocalcaemia in our thyrotoxic patients, and "hungry bone syndrome" may be important as well. Antithyroid medication should reverse osteodystrophy before operation, this reversal takes up to weeks, whereas most our patients were prepared for a much shorter period.

Özet

Tiroid cerrahisi sonrası postoperatif hipokalsemi yaygındır ve sıklıkla geçicidir. Bu durum hastanede kalış süresini ve biyokimyasal tetkik ihtiyacını arttırdığından tiroidektominin maliyetini de yükseltmektedir. Abant Izzet Baysal Tıp Fakültesi'nde 2003-2007 yılları arasında opere edilen 111 hastada tiroidektomi sonrası kalıcı hipoparatirodizm ve hipokalsemi insidansı retrospektif olarak değerlendirildi. Çalışmada postoperatif hipokalsemili hastaların erken biyokimyasal ve klinik bulguları, uzun dönem sonuçlarla ilişkilendirildi. Hastaların 44'ünde postoperatif kalsiyum düzeyinin 8mg/dl altında olduğu gözlendi. On hastada hipokalsemi semptomatikti. Cerrahi girişimden 6 ay sonra 3 (%2.7) hastada kalıcı hipokalsemi mevcuttu. Hipertiroidisi olan hastaların geçici hipokalsemi yönünden daha yüksek risk taşıdığı saptandı (p=0031). Hipertiroidisi olan hastalardaki hipokalsemide, hipoparatiroididen daha çok 'Aç Kemik Sendromu'nun etkisi önemli olabilir. Operasyon öncesi, antitiroid tedavi osteodistrofiyi geri döndürebilir, bu geridönüş haftalar alabilir, oysa hastalarımızın çoğu daha kısa sürede hazırlandı.

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Cite This Article

KAHRAMANSOY, N., KIYAN, A., ÇÖL, C., ŞENGÜL, N., HASDEMİR, A. O., KORDON, Ö., ERKOL, H., TÜRKELİ, V. (2022). Hypocalcaemia after thyroidectomy for thyrotoxicosis. Endokrinolojide Diyalog Dergisi, Cilt: 6 - Sayı: 1, 33–37. https://ajindex.com/articles/500801

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