Journals / Endokrinolojide Diyalog Dergisi / 2012 / Cilt: 9 - Sayı: 3

Effectiveness of elastography in the differential diagnosis of benign and malign thyroid nodules and its comparison with fine needle aspiration biopsy

Tiroid nodüllerinin benign-malign ayırıcı tanısında elastografinin etkinliği ve ince iğne aspirasyon biyopsisi ile kıyaslanması

Pages
103–107
Publication Date
2022-10-11
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Especially it can be beneficial for follicular lesions and some cases with undetermined FNAB results in differential diagnosis.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: The purpose of this study is to compare thyroid elastography, which was performed to patients who were diagnosed with thyroid nodule and indicated operation, with FNAB and histopatology results and to define its efficiency in early preoperative period of thyroid cancer.
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Key Findings & Data:Material and method: Sixteen patients, who applied to our clinic between September 2010-August 2011 with thyroid nodule diagnosis and indicated operation, have been evaluated prospectively.
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Conclusion & Impact:Especially it can be beneficial for follicular lesions and some cases with undetermined FNAB results in differential diagnosis.
🔬Design:Research Article
📍Scope:2010 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: The purpose of this study is to compare thyroid elastography, which was performed to patients who were diagnosed with thyroid nodule and indicated operation, with FNAB and histopatology results and to define its efficiency in early preoperative period of thyroid cancer. Material and method: Sixteen patients, who applied to our clinic between September 2010-August 2011 with thyroid nodule diagnosis and indicated operation, have been evaluated prospectively. Thyroid nodule elastography and FNAB were performed to all patients in preoperative period. Sensitivity, specificity, positive and negative predictive values in FNAB and elastography, which were applied to thyroid nodules, have been determined by comparing elastography and FNAB results with postoperative histopatology results. Results: Sensitiviy, specificity, positive prediction value and negative prediction value of elastography and FNAB in carcinoma determination are, 58.3%, 85.4%, 50%, 89.1% and 83.3%, 89.6%, 66.6%, 95.5%, respectively. Conclusion: Even though sensitivity and specificity values of elastography in preoperative diagnosis of thyroid nodules were determined to be lower in comparison with FNAB, elastography is a new supplementary diagnostic method in preoperative diagnosis of thyroid nodules. Especially it can be beneficial for follicular lesions and some cases with undetermined FNAB results in differential diagnosis.

Özet

Amaç: Bu çalışmanın amacı, tiroid nodülü tanısıyla ameliyat endikasyonu konulan hastalara yapılan tiroid ultrason elastografinin, ince iğne aspirasyon biyopsisi (İİAB) ve histopatoloji sonuçlarıyla karşılaştırarak, tiroid kanserinin preoperatif dönemde belirlenmesindeki etkinliğinin araştırılmasıdır. Gereç ve yöntem: Kliniğimize, Eylül 2010Ağustos 2011 döneminde tiroid nodülü tanısıyla başvurarak ameliyat endikasyonu konulan 60 hasta prospektif olarak değerlendirildi. Tüm olgulara preoperatif dönemde tiroid nodül elastografisi ve İİAB yapıldı. Elastografi ve İİAB sonuçları postoperatif histopatoloji sonuçları karşılaştırılarak, tiroid nodüllerine uygulanan İİAB ve elastografinin duyarlılık, özgüllük, pozitif ve negatif kestirim değerleri belirlendi. Bulgular: Elastografinin karsinom belirlemedeki duyarlılığı %58,3, özgüllüğü %85,4, pozitif kestirim değeri %50, negatif kestirim değeri %89,1 olarak bulundu. İİABnin kanser belirlemedeki duyarlılığı %83,3, özgüllüğü %89,6, pozitif kestirim değeri %66,6, negatif kestirim değeri %95,5 olarak bulundu. Sonuç: Tiroid nodüllerinin preoperatif tanısında elastografinin duyarlılık ve özgüllük değerleri İİAB ne göre daha düşük bulunmuştur. Buna rağmen elastografi, tiroid nodüllerinin preoperatif tanısında kullanılabilecek yeni bir ek tanı yöntemidir. Özellikle folliküler lezyonlarda ve İİAB sonucu belirsiz olan olgularda ayırıcı tanıda yararlı olabilir. Laparoskopik bilateral transperitoneal adrenalektomi; adrenal bezin bilateral çıkarılması gereken durumlarda deneyimli merkezlerde güvenli ve kolay uygulanabilir seçkin bir yöntemdir.

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Cite This Article

KILIÇ, Y., HOT, S., ERTÜRK, A., BENDER, Ö. (2022). Effectiveness of elastography in the differential diagnosis of benign and malign thyroid nodules and its comparison with fine needle aspiration biopsy. Endokrinolojide Diyalog Dergisi, Cilt: 9 - Sayı: 3, 103–107. https://ajindex.com/articles/500747

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