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Journals / Eklem Hastalıkları ve Cerrahisi Dergisi (Eski Adı: Artroplasti Artroskopik Cerrahi Derg.) / 2012 / Cilt: 23 - Sayı: 2

Is single-dose local anesthetic chondrotoxic?

Tek doz lokal anestezik kıkırdağa zarar verir mi?

O Şahap ATİK
Pages
111–112
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The outcome of a single intraarticular injection of local anesthetics remains unclear and requires further investigation.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Intraarticular injection of local anesthetics is widely used in the pain management during and following arthroscopic surgery.
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Key Findings & Data:In recent years, basic scientific studies have demonstrated local anesthetic chondrotoxicity in vivo and in vitro in both human and animal cartilage.
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Conclusion & Impact:The outcome of a single intraarticular injection of local anesthetics remains unclear and requires further investigation.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Intraarticular injection of local anesthetics is widely used in the pain management during and following arthroscopic surgery. In recent years, basic scientific studies have demonstrated local anesthetic chondrotoxicity in vivo and in vitro in both human and animal cartilage. There are some evidences suggesting a higher risk for chondrotoxicity with a longer exposure to a higher concentration of local anesthetics. The outcome of a single intraarticular injection of local anesthetics remains unclear and requires further investigation.

Özet

Artroskopik cerrahi sırasında veya sonrasında oluşan ağrının kontrolünde lokal anesteziklerin eklem içi enjeksiyonu sıkça kullanılır. Son yıllarda, lokal anesteziklerin insan ve hayvan kıkırdaklarına zararlarını gösteren in vivo ve in vitro temel bilimsel çalışmalar yapılmıştır. Lokal anesteziklerin yüksek doz ve uzun süre kullanıldığında kıkırdak hasarının daha fazla olduğunu düşündüren kanıtlar vardır. Tek doz lokal anesteziklerin eklem içi enjeksiyonları sonrasında oluşan durum henüz kesinlik kazanmamıştır; daha çok araştırmaya gereksinim vardır

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Cite This Article

ATİK, O. Ş. (2022). Is single-dose local anesthetic chondrotoxic?. Eklem Hastalıkları ve Cerrahisi Dergisi (Eski Adı: Artroplasti Artroskopik Cerrahi Derg.), Cilt: 23 - Sayı: 2, 111–112. https://ajindex.com/articles/498656

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References (1)

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