Journals / Eklem Hastalıkları ve Cerrahisi Dergisi (Eski Adı: Artroplasti Artroskopik Cerrahi Derg.) / 2016 / Cilt: 27 - Sayı: 2

Agresif osteoblastomun osteosarkoma malign transformasyonu

Malignant transformation of aggressive osteoblastoma to ostesarcoma

Pages
108–112
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As some other cases in the literature, our case indicates that osteoblastomas may undergo malignant transformation.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Osteoblastoma is a rare, bone-forming tumor, characterized by osteoid and woven bone production.
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Key Findings & Data:A 13-year old boy patient presented to our clinic with complaint of pain in his left proximal tibia.
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Conclusion & Impact:As some other cases in the literature, our case indicates that osteoblastomas may undergo malignant transformation.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Osteoblastoma is a rare, bone-forming tumor, characterized by osteoid and woven bone production. A 13-year old boy patient presented to our clinic with complaint of pain in his left proximal tibia. We performed curettage and bone grafting for the lesion diagnosed as osteoblastoma. Two years later, the patient admitted to the hospital with a mass in the same region which was diagnosed by biopsy to be osteosarcoma. Patient was performed reconstruction operation with local resection and mega prosthesis. Fourteen months after termination of chemotherapy, lung metastasis developed and the patient died consequently. In this article, we reported a patient with aggressive osteoblastoma of the left proximal tibia which recurred as an osteosarcoma and discussed the difficulties in the histopathological diagnosis and management of these patients. As some other cases in the literature, our case indicates that osteoblastomas may undergo malignant transformation.

Özet

Osteoblastom osteoid ve örgümsü kemik üretimi ile karakterize, nadir, kemik oluşturan bir tümördür. On üç yaşında erkek hasta sol proksimal tibiasında ağrı yakınması ile kliniğimize başvurdu. Osteoblastom tanısı konulan lezyona küretaj ve kemik greftleme uygulandı. İki yıl sonra, hasta aynı bölgede kitle ile hastaneye başvurdu ve biyopside kitleye osteosarkom tanısı konuldu. Hastaya lokal rezeksiyon ve mega protez ile rekonstrüksiyon ameliyatı yapıldı. Kemoterapinin bitiminden 14 ay sonra, akciğer metastazı gelişti ve ardından hasta kaybedildi. Bu çalışmada sol proksimal tibiada osteosarkom şeklinde nüks eden agresif osteoblastomlu bir hasta sunuldu ve histopatolojik tanıdaki ve bu hastaların yönetimindeki zorluklar tartışıldı. Olgumuz, literatürdeki diğer bazı olgular gibi osteoblastomların malign transformasyon geçirebileceğini göstermektedir.

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Cite This Article

GÖRGÜN, Ö., SALDUZ, A., KEBUDİ, R., BİLGİÇ, B., ÖZGER, H. (2022). Agresif osteoblastomun osteosarkoma malign transformasyonu. Eklem Hastalıkları ve Cerrahisi Dergisi (Eski Adı: Artroplasti Artroskopik Cerrahi Derg.), Cilt: 27 - Sayı: 2, 108–112. https://ajindex.com/articles/498530

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