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Journals / Eklem Hastalıkları ve Cerrahisi Dergisi (Eski Adı: Artroplasti Artroskopik Cerrahi Derg.) / 2019 / Cilt: 30 - Sayı: 3

The effects of focal brain damage on fracture healing: An experimental rat study

Fokal beyin hasarının kırık iyileşmesine etkileri: Deneysel bir sıçan çalışması

Yakup EKİNCİ
Mustafa ARIK
Kaan GÜRBÜZ
Sabri BATIN
Pages
267–274
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There was a statistically significant difference incallus/diaphysis ratio between control, MC and SC groups infavor of MC group only at one week (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: This study aims to investigate whether the motorcortex (MC) or the somatosensory cortex (SC) is more activeduring the course of bone healing after traumatic brain injury(TBI).Materials and methods: Thirty-three male Wistar albinorats (age, 8 to 10 months; weighing, 250 to 300 g) wererandomized into three groups as the control group, MCdamage group and SC damage group.
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Key Findings & Data:Callus formation, callus/diaphysis ratios,and serum alkaline phosphatase (ALP) levels were measuredat one, three and six weeks.Results: The increases in callus masses in the control,MC, and SC groups were statistically significantly differentbetween one and three weeks (p0.05).
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Conclusion & Impact:There was a statistically significant difference incallus/diaphysis ratio between control, MC and SC groups infavor of MC group only at one week (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: This study aims to investigate whether the motorcortex (MC) or the somatosensory cortex (SC) is more activeduring the course of bone healing after traumatic brain injury(TBI).Materials and methods: Thirty-three male Wistar albinorats (age, 8 to 10 months; weighing, 250 to 300 g) wererandomized into three groups as the control group, MCdamage group and SC damage group. Two rats from eachbrain damage group were sacrificed to verify the locations ofthe cortical injuries. Callus formation, callus/diaphysis ratios,and serum alkaline phosphatase (ALP) levels were measuredat one, three and six weeks.Results: The increases in callus masses in the control,MC, and SC groups were statistically significantly differentbetween one and three weeks (p0.05). There was a statistically significant difference incallus/diaphysis ratio between control, MC and SC groups infavor of MC group only at one week (p

Özet

Amaç: Bu çalışmada travmatik beyin yaralanması (TBY) sonrası kırık iyileşmesi süresince motor korteks (MK)’in mi yoksa somatosensöriyel korteks (SK)’in mi daha aktif olduğu araştırıldı. Gereç ve yöntemler: Otuz üç erkek Wistar albino sıçan (yaş, 8-10 ay; ağırlık, 250-300 g) kontrol grubu, MK hasar grubu ve SK hasar grubu olarak üç gruba randomize edildi. Kortikal yaralanmaların yerlerini doğrulamak için her beyin hasarı grubundan iki sıçan sakrifiye edildi. Kallus oluşumu, kallus/diyafiz oranları ve serum alkalen fosfataz (ALP) düzeyleri bir, üç ve altıncı haftalarda ölçüldü. Bulgular: Kontrol, MK ve SK gruplarında kallus kitlelerindeki artışlar bir ve üç hafta arasında istatistiksel olarak anlamlı şekilde farklı idi (p0.05). Kontrol, MK ve SK grupları arasında kallus/diyafiz oranı açısından sadece bir haftada MK grubu lehine istatistiksel olarak anlamlı farklılık vardı (p

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Cite This Article

EKİNCİ, Y., ARIK, M., GÜRBÜZ, K., BATIN, S. (2022). The effects of focal brain damage on fracture healing: An experimental rat study. Eklem Hastalıkları ve Cerrahisi Dergisi (Eski Adı: Artroplasti Artroskopik Cerrahi Derg.), Cilt: 30 - Sayı: 3, 267–274. https://ajindex.com/articles/498399

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