SavedAdd your journal

Journals / E Journal of Cardiovascular Medicine / 2021 / Cilt: 9 - Sayı: 2

High Triglyceride Glucose Index Does Not Show the Presence and Severity of Coronary Artery Disease: A Single- Center Study

Musa ŞANLIALP
Sara Çetin ŞANLIALP
Gökay NAR
Gürsel ŞEN
Mehmet Güven GÜNVER
Pages
76–82
Publication Date
2022-10-12
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

When the subjects were divided according to the TyG index, those with high TyG index had a higher incidence of hypertension, diabetes, and lipid parameters deterioration (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objectives: The triglyceride glucose index (TyG index) calculated by fasting plasma glucose and triglycerides is associated with hypertension, diabetes and metabolic syndrome (MetS).
📊
Key Findings & Data:Materials and Methods: Eighty-three ACS patients (mean age: 64.64±12.79 years; male gender, 65%) and 50 control subjects with normal coronary arteries (58.50±12.28 years, male, 56%) were analyzed, retrospectively.
💡
Conclusion & Impact:When the subjects were divided according to the TyG index, those with high TyG index had a higher incidence of hypertension, diabetes, and lipid parameters deterioration (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: The triglyceride glucose index (TyG index) calculated by fasting plasma glucose and triglycerides is associated with hypertension, diabetes and metabolic syndrome (MetS). However, the studies investigating the role of the TyG index in coronary artery disease (CAD) are limited and conflicting. In this study, we aimed to determine the role of the TyG index in the presence and severity of CAD in patients with acute coronary syndrome (ACS). Materials and Methods: Eighty-three ACS patients (mean age: 64.64±12.79 years; male gender, 65%) and 50 control subjects with normal coronary arteries (58.50±12.28 years, male, 56%) were analyzed, retrospectively. The severity of CAD was evaluated by Gensini and SYNTAX I scores and p 0.05). When the subjects were divided according to the TyG index, those with high TyG index had a higher incidence of hypertension, diabetes, and lipid parameters deterioration (p

🔖

Cite This Article

ŞANLIALP, M., ŞANLIALP, S. Ç., NAR, G., ŞEN, G., GÜNVER, M. G. (2022). High Triglyceride Glucose Index Does Not Show the Presence and Severity of Coronary Artery Disease: A Single- Center Study. E Journal of Cardiovascular Medicine, Cilt: 9 - Sayı: 2, 76–82. https://ajindex.com/articles/498217

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (12)

  1. Smith SC Jr, Jackson R, Pearson TA, et al. Principles for national and regional guidelines on cardiovascular disease prevention: a scientific statement from the World Heart and Stroke Forum. Circulation 2004;109:3112-21
  2. Lee EY, Yang HK, Lee J, et al. Triglyceride glucose index, a marker of insulin resistance, is associated with coronary artery stenosis in asymptomatic subjects with type 2 diabetes. Lipids Health Dis 2016;15:155
  3. Kim JH, Lee DY, Park SE, et al. Triglyceride glucose index predicts coronary artery calcification better than other indices of insulin resistance in Korean adults: the Kangbuk Samsung Health Study. Precision and Future Medicine 2017;1:43-51
  4. Wang L, Cong HL, Zhang JX, et al. Triglyceride-glucose index predicts adverse cardiovascular events in patients with diabetes and acute coronary syndrome. Cardiovasc Diabetol 2020;19:80
  5. Simental-Mendía LE, Rodríguez-Morán M, Guerrero-Romero F. The product of fasting glucose and triglycerides as surrogate for identifying insulin resistance in apparently healthy subjects. Metab Syndr Relat Disord 2008;6:299-304
  6. Roffi M, Patrono C, Collet JP, et al. 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation of the European Society of Cardiology (ESC). Eur Heart J 2016;37:267-315
  7. Chalmers J, MacMahon S, Mancia G, et al. 1999 World Health Organization- International Society of Hypertension Guidelines for the Management of Hypertension. Guidelines sub-committee of the World Health Organization. Clinical and Experimental Hypertansion. 1999;21:1009-60
  8. American Diabetes Association
  9. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes-2019. Diabetes Care 2019;42(Suppl 1):13-28.9. SYNTAX working group. SYNTAX score calculator. Available at http:// www.syntaxscore.com. Accessed May 20, 2012
  10. Gensini GG. A more meaningful scoring system for determining the severity of coronary heart disease. Am J Cardiol 1983;51:606
  11. Linton MF, Fazio S. Macrophages, inflammation, and atherosclerosis. Int J Obes Relat Metab Disord 2003;27:35-40
  12. Yamazoe M, Hisamatsu T, Miura K, et al. Relationship of Insulin Resistance to Prevalence and Progression of Coronary Artery Calcification Beyond Metabolic Syndrome Components: Shiga Epidemiological Study of Subclinical Athe