Journals / Ege Tıp Dergisi / 2018 / Cilt: 57 - Sayı: 4

Impact of contact lens wear on ocular surface and Meibomian glands

Kontakt lens kullanımının oküler yüzey ve Meibomian bezleri üzerine etkileri

Pages
191–194
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Meiboscoring is an effective and practical way for evaluation of the MG.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: To determine the impact of contact lens (CL) wear on the ocular surface and Meibomian glands (MG).
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Key Findings & Data:Materials and Methods: 24 silicone hydrogel CL wearers for a minimum of 5 years (Group 1) and 26 healthy volunteers (Group 2) were included in this retrospective study.
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Conclusion & Impact:Meiboscoring is an effective and practical way for evaluation of the MG.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: To determine the impact of contact lens (CL) wear on the ocular surface and Meibomian glands (MG). Materials and Methods: 24 silicone hydrogel CL wearers for a minimum of 5 years (Group 1) and 26 healthy volunteers (Group 2) were included in this retrospective study. Best corrected visual acuity, Oxford scoring, tear film break-up time (T-BUT), Schirmer 1 test, Ocular Surface Disease Index (OSDI) scoring and MG evaluation by infrared captures of optic coherence tomography (OCT) were performed. Loss of the MG was scored blindly by a single researcher. Results: The mean age was 30.00±6.22 in Group 1 and 28.70±4.95 in Group 2 (p=0.300). Male/female ratio was 4/20 in Group 1 and 9/17 in Group 2. The average duration of CL wear was 10.70±2.70 years. The mean T-BUT in Group 1 and 2 were 17.70±76.74 and 24.76±8.06 sec, respectively (p=0.002). The mean Schirmer 1 test in Group 1 and 2 were 29.04±7.67 and 25.50±8.48 mm, respectively (p=0.129). The mean Oxford scale staining in Group 1 and 2 were 0.58±0.94 and 0.15±0.41, respectively (p=0.040). The mean OSDI scores in Group 1 and 2 were 29.36±19.25 and 23.63±21.99, respectively (p=0.334). The average upper, lower eyelid, and total meiboscores in Group 1 and 2 were 0.95±0.87, 0.66±0.73, 1.60±1.40 and 0.67±0.59, 0.67±0.70 and 1.34±1.17, respectively. No statistical significance was detected in any of these scores. Conclusion: CL wear has a variety of effects on ocular surface. MG has a significant influence on ocular surface. Meiboscoring is an effective and practical way for evaluation of the MG.

Özet

Amaç: Yumuşak kontakt lens (KL) kullanımının oküler yüzey ve Meibomian bezleri üzerine etkisini araştırmak Gereç ve Yöntem: Beş yılı aşkın süredir silikon hidrojel KL kullanım öyküsü bulunan 24 olgu (Grup 1) ve 26 sağlıklı gönüllünün (Grup 2) en iyi düzeltilmiş görme keskinlikleri, Schirmer 1 testi, gözyaşı kırılma zamanı, oküler yüzey boyanması (Oxford skalası), OSDI skoru ve meibomian bez özelliklerini içeren kayıtları retrospektif olarak değerlendirildi. Üst ve alt kapakların OCT meibografileri (Spectralis HRA+OCT; Heidelberg Engineering, Heidelberg, Germany) çekilerek bez kaybı açısından tek bir araştırmacı tarafından kör olarak değerlendirildi. Bulgular: Ortalama yaş Grup 1’de 30.00±6.22, Grup 2’de ise 28.70±4.95 idi (p=0.300). Erkek/kadın oranı Grup 1’de 4/20, Grup 2’de 9/17 idi. KL kullanım süresi 10.70±2.70 yıldı. Ortalama gözyaşı kırılma zamanı Grup 1’de 17.70±76.74, Grup 2’de 24.76±8.06 saniyeydi (p=0.002). Ortalama Schirmer 1 değeri Grup 1’de 29.04±7.67, Grup 2’de 25.50±8.48 mm idi (p=0.129). Oxford skalası puanı Grup 1’de 0.58±0.94, Grup 2’de 0.15±0.41 olup fark istatistiksel olarak anlamlıydı (p=0.040). OSDI skoru açısından gruplar arası istatistiksel anlamlı fark bulunmamaktaydı (Grup 1: 29.36±19.25, Grup 2: 23.63±21.99, p=0.334). Üst, alt kapak ve toplam meibomian bez skoru ortalaması Grup 1’de sırasıyla 0.95 ±0.87, 0.66±0.73 ve 1.60±1.40, Grup 2’de sırasıyla 0.67 ± 0.59, 0.67 ±0.70 ve 1.34±1.17 idi ve aralarındaki fark istatistiksel olarak anlamlı değildi. Sonuç: Uzun süreli KL kullanımının, oküler yüzeye birçok farklı etkisi mevcuttur. Meibomian bezler, oküler yüzeye önemli etkileri bulunan yapıladır. Meibobian bez skorlaması, Meibomian bez değerlendirmesi için etkili ve pratik bir yöntemdir.

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Cite This Article

PALAMAR, M., MENTEŞ, J., YAĞCI, A., SELVER, Ö. B. (2022). Impact of contact lens wear on ocular surface and Meibomian glands. Ege Tıp Dergisi, Cilt: 57 - Sayı: 4, 191–194. https://ajindex.com/articles/496174

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References (16)

  1. Knop N, Knop E. Meibomian glands. Part I. Anatomy, embryology and histology of the Meibomian glands. Ophthalmologe 2009;106(10):872-83
  2. Nagyova B, Tiffany JM. Components responsible for the surface tension of human tears. Curr Eye Res 1999;19(1):4-11
  3. Craig JP, Tomlinson A. Importance of the lipid layer in human tear film stability and evaporation. Optom Vis Sci 1997;74(1):8-13
  4. Nelson JD, Shimazaki J, Benitez-del-Castillo JM, et al. The international workshop on meibomian gland dysfunction: Report of the definition and classification subcommittee. Invest Ophthalmol Vis Sci 2011;52(4):1930-7
  5. Arita R, Itoh K, Inoue K, Amano S. Noncontact infrared meibography to document age-related changes of the meibomian glands in a normal population. Ophthalmology 2008;115(5):911-5
  6. Pult H, Riede-Pult BH. Non-contact meibography: Keep it simple but effective. Cont Lens Anterior Eye 2012;35(2):77-80
  7. Srinivasan S, Sorbara L, Jones L, Sickenberger W. Imaging the structure of the meibomian glands. Contact Lens Spectrum 2011;7(1):52-3 8. Nichols JJ, Sinnott LT. Tear film, contact lens, and patient- related factors associated with contact lens-related dry eye. Invest Ophthalmol Vis Sci 2006;47(4):1319-28
  8. Pisella PJ, Malet F, Lejeune S, et al. Ocular surface changes induced by contact lens wear. Cornea 2001;20(8):820-5
  9. Hatfield RO, Jordan DR, Bennett ES, Henry VA, Marohn JW, Morgan BW. Initial comfort and surface wettability: A comparison between different contact lens materials. J Am Optom Assoc 1993;64(4):271-3
  10. Nichols JJ, Mitchell GL, Nichols KK, Chalmers R, Begley C. The performance of the contact lens dry eye questionnaire as a screening survey for contact lens-related dry eye. Cornea 2002;21(5):469-75
  11. Begley CG, Caffery B, Nichols KK, Chalmers R. Responses of contact lens wearers to a dry eye survey. Optom Vis Sci 2000;77(1):40-6
  12. Arita R, Itoh K, Inoue K, Kuchiba A, Yamaguchi T, Amano S. Contact lens wear is associated with decrease of meibomian glands. Ophthalmology 2009;116(3):379-84
  13. Ngo W, Srinivasan S, Jones L. Historical overview of imaging the meibomian glands. Journal of Optometry 2013;6(1):1-8
  14. Nichols JJ, Berntsen DA, Mitchell GL, Nichols KK. An assessment of grading scales for meibography images. Cornea 2005;24(4):382-8
  15. Shimazaki J, Goto E, Ono M, Shimmura S, Tsubota K. Meibomian gland dysfunction in patients with Sjögren syndrome. Ophthalmology 1998;105(8):1485-8
  16. Goto E, Monden Y, Takano Y, et al