Journals / Ege Tıp Dergisi / 2021 / Cilt: 60 - Sayı: Supplement

Diffuse alveolar hemorrhage

Diffüz alveoler hemoraji

Pages
53–55
Publication Date
2022-10-17
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Treatments of the underlying disease as well as immunosuppressive therapy especially high-dose corticosteroids are important in treatment of DAH.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Diffuse alveolar hemorrhage (DAH) is accumulation of erythrocytes into the alveoli and is often caused by pulmonary microcirculation resulting in systemic vasculitis.
📊
Key Findings & Data:Immune and non-immune causes are responsible for DAH etiology.
💡
Conclusion & Impact:Treatments of the underlying disease as well as immunosuppressive therapy especially high-dose corticosteroids are important in treatment of DAH.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Diffuse alveolar hemorrhage (DAH) is accumulation of erythrocytes into the alveoli and is often caused by pulmonary microcirculation resulting in systemic vasculitis. Immune and non-immune causes are responsible for DAH etiology. Hemoptysis and dyspnea are the most common clinical symptoms. Bilateral ground-glass opacity is seen at chest x-ray. Hemogram, renal function tests and immunological markers are diagnostic laboratory tests. Diagnosis is made by macroscopic and microscopic findings of bronco-alveolar lavage fluid. Treatments of the underlying disease as well as immunosuppressive therapy especially high-dose corticosteroids are important in treatment of DAH.

Özet

Diffüz alveoler hemoraj (DAH) pulmoner mikro-sirkülasyondan kaynaklanan, sıklıkla sistemik bir vaskülitin neden olduğu, alveol içine eritrosit birikmesidir. DAH etiyolojisinde immün ve non-immün nedenler sorumludur. Hemoptizi ve nefes darlığı en sık karşılaşılan klinik semptomlardır. Akciğer grafisinde bilateral buzlu cam dansiteleri izlenir. Hemogram, böbrek fonksiyon testleri ve immünolojik belirteçler tanıya yardımcı laboratuvar testleridir. Bronko-alveoler lavaj sıvısının makroskopik ve mikroskobik bulguları ile tanı konulur. Tedavisinde altta yatan hastalığın tedavisi yanı sıra, yüksek doz kortikosteroid başta olmak üzere immünsupresif tedavi önem taşır.

🔖

Cite This Article

Taşbakan, M. S. (2022). Diffuse alveolar hemorrhage. Ege Tıp Dergisi, Cilt: 60 - Sayı: Supplement, 53–55. https://ajindex.com/articles/496072

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (7)

  1. Taşbakan MS, Özdemir Ö, Yıldız BS, Özerkan F, Bacakoğlu F. Varfarin toksisitesi ve amiodaron tedavisi ile ilişkili iki alveoler hemoraji sendromu olgusu. Yoğun Bakım Dergisi 2010; 9 (1): 57-63
  2. Krause ML, Cartin-Ceba R, Specks U, Peikert T. Update on diffuse alveolar hemorrhage and pulmonary vasculitis. Immunol Allergy Clin North Am 2012; 32 (4): 587-600
  3. Quadrelli S, Diana D, Solis M, et al. Immune diffuse alveolar hemorrhage: clinical presentation and outcome. Respiratory Medicine 2017; 129: 59-62
  4. Gürgün A, Köşker P, Susur A, et al. Diffüz alveoler hemoraji sendromlarında mortaliteyi etkileyen faktörler. Türkiye Klinikleri Arch Lung 2009; 10 (2): 39-44
  5. Picard C, Cadranel J, Porcher R, et al. Alveolar haemorrhage in the immunocompetent host: a scale for early diagnosis of an immune cause. Respiration 2010; 80: 313-20
  6. Lichtenberger JP, Digumarthy SR, Abbott GF, Shepard JA, Sharma A. Diffuse pulmonary hemorrhage: clues to the diagnosis. Curr Probl Diagn Radiol 2014; 43: 128-39
  7. Ednalino C, Yip J, Carsons SE. Systematic review of diffuse alveolar hemorrhage in systemic lupus erythematosus: focus on outcome and therapy. J Clin Rheumatol 2015; 21: 305-10.