Journals / Ege Pediatri Bülteni / 2001 / Cilt: 8 - Sayı: 4

Three children with pulmonary embolism treated with anticoagulant and thrombolytic agents

Pulmoner emboli tanısı ile antikoagülan ve trombolitik tedavi uygulanan üç çocuk olgu

Pages
217–223
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This article reports three children with pulmonary embolism treated with three different thrombolytic agents.

📌 3 Key Takeaways

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Objective & Hypothesis:In children, the diagnosis of pulmonary embolism is seldom considered and many pulmonary embolism remain undiagnosed until postmortem examinations are performed.
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Key Findings & Data:Some acquired (presence of a central venous catheter, immobility, trauma, infection, neoplasia e.g) and congenital (active protein C resistance, deficiencies of activity of antithrombin, protein C and protein S) risk factors predispose pediatric patients to pulmonary embolism.
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Conclusion & Impact:This article reports three children with pulmonary embolism treated with three different thrombolytic agents.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

In children, the diagnosis of pulmonary embolism is seldom considered and many pulmonary embolism remain undiagnosed until postmortem examinations are performed. Some acquired (presence of a central venous catheter, immobility, trauma, infection, neoplasia e.g) and congenital (active protein C resistance, deficiencies of activity of antithrombin, protein C and protein S) risk factors predispose pediatric patients to pulmonary embolism. In the diagnosis of pulmonary embolism, ventilation-perfusion imaging has a great importance but sometimes may be insufficient and the other diagnostic procedures such as spiral computarized tomography, magnetic resonance imaging may be necessary. Heparin is the major therapetic agent in the acute treatment. Sometimes urokinase, streptokinase or tissue plasminogen activator are added to therapy. This article reports three children with pulmonary embolism treated with three different thrombolytic agents.

Özet

Çocuklarda pulmoner emboli tanısı nadiren akla gelir ve pulmoner ambolilerin önemli bir bölümü otopsi yapılana dek tanınamaz. Bazı edinsel ve konjenital risk faktörleri çocuklarda pulmoner emboli gelişimine zemin hazırlar (santral venöz katater varlığı, immobilizasyon, travma, infeksiyon, neoplazi, aktive protein C direnci, antitrombin, protein C ve protein S aktivite eksikliği gibi). Pulmoner emboli tanısında ventilasyon-perfüzyon sintigrafisi çok büyük önem taşır ancak bazen yeterli olmayabilir ve spiral bilgisayarlı tomografi veya manyetik rezonans görüntüleme gibi diğer tanısal araçlara gerek duyulabilir. Akut tedavide heparin esas ajandır. Bazen ek olarak ürokinaz, streptokinaz, doku plasminojen aktivatörü gibi trombolitik ajanlar kullanılabilir. Bu çalışmada pulmoner emboli saptanan ve 3 farklı trombolitik ajanla tedavi edilen 3 ayrı hasta sunulmaktadır.

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Cite This Article

YILMAZ, D., ALPER, H., KARAPINAR, B., AYDINOK, Y., BALKAN, C., KAVAKLI, K. (2022). Three children with pulmonary embolism treated with anticoagulant and thrombolytic agents. Ege Pediatri Bülteni, Cilt: 8 - Sayı: 4, 217–223. https://ajindex.com/articles/495872

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