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Journals / Ege Pediatri Bülteni / 2003 / Cilt: 10 - Sayı: 2

Infective endocarditis, glomerulonephritis and myelofibrosis developing as a complication of ventriculoatrial shunt: The role of immune complexes in pathogenesis

Ventrikülo-atriyal şant komplikasyonu olarak gelişen enfektif endokardit, glomerülonefrit ve myelofibrozis: Patogenezde immun komplekslerin rolü

Mustafa BAK
Mithat KUŞKAYA
Gökmen BİLGİLİ
Tuğrul ÖZCAN
Ragıp ORTAÇ
Canan VERGİN
Şebnem ÇALKAVUR
Sait ŞEN
Pages
103–106
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this article, a case with coexistent infective endocarditis, glomerulonephritis and myelofibrosis developing as a complication of an infected ventriculoatrial shunt presented and the pathogenesis of this association is discussed.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Shunt nephritis is known as glomerulonephritis developing as a result of the infection of the shunts placed for hydrocephalus.
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Key Findings & Data:Glomerular disease associated with myelofibrosis is rarely described, and immune complexes are thought to be responsible in the pathogenesis of both disorders.
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Conclusion & Impact:In this article, a case with coexistent infective endocarditis, glomerulonephritis and myelofibrosis developing as a complication of an infected ventriculoatrial shunt presented and the pathogenesis of this association is discussed.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Shunt nephritis is known as glomerulonephritis developing as a result of the infection of the shunts placed for hydrocephalus. Glomerular disease associated with myelofibrosis is rarely described, and immune complexes are thought to be responsible in the pathogenesis of both disorders. In this article, a case with coexistent infective endocarditis, glomerulonephritis and myelofibrosis developing as a complication of an infected ventriculoatrial shunt presented and the pathogenesis of this association is discussed.

Özet

Hidrosefali nedeniyle yerleştirilen santiarın enfekte olması sonucu gelişen glomerülonefrit şant nefriti olarak bilinmektedir. Glomerüler hastalıkla ilişkili myelofibrozis nadiren tanımlanmış olup, bu hastalıkların patogenezinde immun komplekslerin rolü üzerinde durulmuştur. Bu yazıda enfekte ventrikülo-atriyal şant komplikasyonu olarak gelişen enfektif endokardit, glomerülonefrit ve myelofibrozis birlikteliği olan olgu sunulmuş ve bu birlikteliğin patogenezi tartışılmıştır.

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Cite This Article

BAK, M., KUŞKAYA, M., BİLGİLİ, G., ÖZCAN, T., ORTAÇ, R., VERGİN, C., ÇALKAVUR, Ş., ŞEN, S. (2022). Infective endocarditis, glomerulonephritis and myelofibrosis developing as a complication of ventriculoatrial shunt: The role of immune complexes in pathogenesis. Ege Pediatri Bülteni, Cilt: 10 - Sayı: 2, 103–106. https://ajindex.com/articles/495825

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References (10)

  1. Black JA, Challacombe DN, Ockenden BG. Nephrotic syndrome associated with bacteraemia after shunt operations for hydrocephalus. Lancet 1965; 2: 921-924
  2. Narchi R, Taylor R, Azmy AF, et al. Shunt nephritis. J Pediatr Surg 1988; 23 (9): 839-841
  3. Bayston R, Rodgers J, Tabara ZB. Ventriculoatrial shunt colonization and immune complex nephritis. Eur J Pediatr Surg 1991; 1 (Suppl 1): 46-47
  4. Gordon BR, Coleman M, Kohen P, et al. Immunologic abnormalities in myelofibrosis with activation of the complement system. Blood 1981; 58: 904-910
  5. Caijo Y, Almange C, Boutin J, et al. Glomerular disease associated with myelofibrosis. Sem Hop 1979; 55 (9-10): 489-493
  6. Rifkinson-Mann S, Rifkinson N, Leong T. Shunt nephritis (case report). J Neurosurg 1991; 74: 656-659
  7. Kim Y, Michael AF, Tarshish P. Infection and nephritis. In: Edelman CM, Jr, ed. Pediatric Kidney Disease. Boston: Little, Brown and Company, 1992: 1569-1584
  8. Cappio FC, Vigliani R, Novarino A, et al. Idiopathic myelofibrosis: a possible role for immune-complexes in the pathogenesis of bone marrow fibrosis. Br J Haematol 1981; 49 (1): 17-21
  9. Lichtman MA. Agnogenic myeloid metaplasia. In: Williams WJ, Beutler E, Erslev AJ, Lichtman MA, eds. Hematology. New York: McGraw Hill, 1991: 223-232
  10. Kaelin WG, Sipivak JL. Systemic lupus erythematosus and myelofibrosis. Am J Med 1986; 81: 935-938.