Journals / Ege Pediatri Bülteni / 2005 / Cilt: 12 - Sayı: 2

Treatment of a case with severe salicylate entoxication

Ağır salisilat zehirlenmesi olan olgunun tedavi yaklaşımı

Pages
111–115
Publication Date
2022-10-17
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The aim of this case report is to discuss in highlights of salicylate intoxication with the clinical presentations and treatment approaches based on the case.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Salicylate poisoning can result in severe morbidity and mortality.
📊
Key Findings & Data:Severe toxicity appears over the dose of 300 mg/kg.
💡
Conclusion & Impact:The aim of this case report is to discuss in highlights of salicylate intoxication with the clinical presentations and treatment approaches based on the case.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Salicylate poisoning can result in severe morbidity and mortality. The clinical presentation is correlated with the dose, and duration of exposing, as well as with the age of patient. Severe toxicity appears over the dose of 300 mg/kg. Early diagnosis and management can reduce the mortality rate to %15 in severe toxicity. We report a 17 years old adolescent male who admitted to the hospital with severe salicylate intoxication resulting from 415mg/kg salicylate intake for suicidal purpose. The aim of this case report is to discuss in highlights of salicylate intoxication with the clinical presentations and treatment approaches based on the case.

Özet

Salisilat zehirlenmesi, şiddetli morbidite ve mortaliteye neden olabilir. Klinik şiddeti, alınan salisilat dozuna, süresine ve hastanın yaşına bağlıdır. Ağır toksisiteden bahsedebilmek için, salisilatın 300 mg/kg'ın üzerinde alınması gereklidir. Ağır salisilat zehirlenmesinde erken tanı ve tedavi, mortaliteyi %15'e kadar azaltmaktadır. Bu sunumda, intihar amaçlı yaklaşık 415 mg/kg salisilat alan, 17 yaşında adölesan erkek hastanın klinik bulgularının dinamik tedavi yaklaşımı ve literatür verileri eşliğinde tartışılması amaçlanmıştır

🔖

Cite This Article

ÖZEN, S., ÖZKAYIN, N., AYDINOK, Y., KABASAKAL, C., YENİAY, B. S., GÜLEN, F. (2022). Treatment of a case with severe salicylate entoxication. Ege Pediatri Bülteni, Cilt: 12 - Sayı: 2, 111–115. https://ajindex.com/articles/495776

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (5)

  1. Dargan PI, Wallace CI, Jones AL. An evidence based flowchart to guide the management of acute salicylate (aspirin) overdose. Emerg Med J 2002; 19 (3): 206-209. Done AK. Aspirin Overdose: incidence. Diagnosis and Management Pediatrics 1978; 62: 895. Dugandzic RM, Tierney MG, Dickinson QE, Dolan MC, McKnight DR. Evaluation of the validity of the Done nomogram in the management of acute salicylate intoxication. Ann Emerg Med 1989; 18(11): 1186-1190. General Practise notebook, www.gpnotebook.co.uk/aspirin poisoning Ellenhom MJ, Ellenhom's Medical Toxicology Diagnosis and Treatment of Human Poising 2nd ed Baltimore Williams & Wilkins 1997: 210-213. Temple AR. Acute and chronic effects of aspirin toxicity and their treatment. Arch Intern Med 1981 23; 141: 364-369.
  2. Winchester JR, Genfand MC, Helliwell M. Extracorporal treatment of salicylate or acetaminofen poisoning is there a role? Arch Intern Med 1981: 23; 141: 370-374. Jacobsen D Wiik - Larsen E. Bredesen JE. Haemodialysis or haemoperfusion in severe salicylate poisoning. Hum Toxicol 1988; 7 (2): 161-163.
  3. Kahveci M, Coşkun Ç, Karasalihlioğlu S Bir üniversite Hastanesi Acil Servisine Başvuran Çocukluk çağı zehirlenmelerinin değerlendirilmesi Sted 2004 Ciltl3 Sayı 1; 21-24.
  4. Lifovitz TL, Klein-Schwartz W, Caravanti EM, Youniss J, Crouch B, Lee S: 1998 annual report of the American Assosiation of poison control centers Toxic Exposure Surveillance System. Am J Emerg Med 1999; 17: 435-487.
  5. Çam H, Kıray E, Taştan Y, Özkan H Istanbul Üniversitesi Cerrahpaşa Tıp Fakültesi Çocuk Sağlığı ve Hastalıkları Anabilim Dalı Acil servisinde izlenen zehirlenme olguları Türk Pediatri Arşivi 2003, Cilt 38, Sayı 4; 233-239.